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Pathogenic Microorganisms
Pathogenic Microorganisms
96
Microbiology
Undergraduate 2
04/13/2012

Additional Microbiology Flashcards

 


 

Cards

Term
Ricksettia
Definition

gram negative rods

obligate intracellular parasites

transmitted by insect bites

illnesses common in Southwest US

Term
Bartonella henselae
Definition

Cat Scratch Fever

normal flora in cat intestines

serious infection - high fever

gram negative rods

direct contact or fleas

Term
Brucella
Definition

small gram negative rods

causes  "undulant fever"

(undulant - comes and goes)

can become airborne

*potential for bioterrorism

Term
Bordetella pertussis
Definition

Whooping Cough

gram negative rods

vaccine DPT

forms a membrane in the throat

Term
Neisseria
Definition

gram negative diplococci

normal flora of mucus membranes

 

N. gonorrheae - gonorrhea

N. meninginitidis - meningitis

 

*N. gonorrheae has protein Opa that binds to CD4 lymphocytes and prevents the production of memory cells and immunity

Term
Francisella tularensis
Definition

tularemia

transmitted by rodents - rabbits, squirrels, hamsters, etc. - bite

infect lymph nodes

can multiply in macrophages

(macrophages in tissue fluid)

difficult to treat

*potential for bioterrorism

Term
Pseudomonas
Definition

gram negative motile rods

can grow in water, on soap, in bottle caps

can grow in refrigerator

common nosocomial infection

can produce a blue-green pigment that smells like grapes

antibiotic resistant - gentamycin

Term
Legionella pneumophilia
Definition

gram negative rods

Legionnaires' disease - high fever & pneumonia

reproduce in aquatic amoebae

Term
Vibrio
Definition

slightly curved gram negative rods

found in salt or brackish water

V. cholera - cholera - very watery stools with intestinal mucus - "rice water" stools - dehydration & death

V. parahemoliticus - gastroenteritis from raw oysters, shrimp, and crabs

Term
Escherichia coli
Definition

inhabits mammalian interstinal tract

wound infections & UTI

 O157:H7 - causes diarrhea and produces a toxin that can shut down the kidneys

Term
Salmonella enterica
Definition

-2400 serovars

-found in intestinal tracts of poultry & cattle, found in reptiles

-can get inside plants we eat

-causes bloody diarrhea

Term
Salmonella typhi
Definition

-causes typhoid fever

-high fever & headache

-can infect the liver & spleen

-some people become carriers (Typhoid Mary)

Term
Shigella
Definition

-spread from person to person

-found on fresh unwashed fruit

-causes dysentery

Term
Klebsiella pneumoniae
Definition

-can cause pneumonia

-commonly causes UTI

(bladder infection - cystitis

kidney infection - pyelonephritis)

Term
Serratia
Definition

-grows in saline

-responsible for many nosocomial infections

Term
Proteus
Definition

-many flagella

-swarming growth on media

-normal intestinal flora

-UTI & wound infections

-smells like chocolate cake

Term
Enterobacter
Definition

-gram negative

-live everywhere

-causes UTIs

Term
Pasturella multocida
Definition

-wound infection from cat bites

-requires IV antibiotics

-causes cellulitis

Term
Haemophilus
Definition

-needs chocolate (hemolyzed blood) agar to grow in the lab

-very pathogenic

-smells mousey

Term
Haemophilus influenza
Definition
-meningitis, ear infection, epiglotitis, pneumonia
Term
Haemophilus ducreyi
Definition
-STD "chancroid"
Term
Haemophilus ageptycus
Definition
-pink eye
Term
Camphylobacter jejunii
Definition

-found in poultry

-must be incubated at 42 degrees Celsius

-causes gastroenteritis

-high fever

Term

Helicobacter spp.

Helicobacter pylori

Definition
-causes peptic ulcers and stomach cancer
Term
Clostridium
Definition

-spore forming anaerobes

-spores can live in the soil for years

 

C. tetani - tetanus (lockjaw)

C. botulinum - botulism

C. perfringens - gas gangrene

C. difficil - antibiotic resistant, normal intestinal flora, when antibiotics kill all good flora it takes over, often a nosocomial infection

Term
Bacillus spp.
Definition

gram positive rods

are everywhere

two are pathogens-

B. cereus (food poisoning)

B.antracis (anthrax)

Term
Bacillus antracis 
Definition

CDC must be notified

Three types of anthrax:

-Cutaneous (skin)

-Gastrointestinal

-Pulmonary

(if not treated can lead to septicemia - death rate 100%)

*potential for bioterror

Term
Staphylococcus aureus
Definition

-gram positive cocci

-grows in grape-like clusters

-yellow colonies

-can grow in salty meats

-grows in ocean

-produces toxins

-MRSA (pg 422)

-causes wound infections, food poisoning, toxic shock syndrome

Term
Streptococcus
Definition

gram positive cocci

-grows in chains

-two important types:

Beta hemolytic

Alpha hemolytic

Term
Streptococcus - beta hemolytic
Definition

form a clear zone around the colony when grown on blood agar

 

-Groups A-O

Term

Streptococcus - beta hemolytic - Group A -

Streptococcus pyogenes

Definition

 

has M protein on surface that helps it avoid phagocytosis

causes most variety of diseases:

sore throats

scarlet fever

rheumantic fever (affects joints & heart)

impetigo

necrotizing fascitis - painful infection that can consume an inch of tissue an hour

Term

Streptococcus - beta hemolytic - Group B

-  Streptococcus agalactiae

Definition

 

 

-causes newborn sepsis

Term
Streptococcus - alpha hemolytic
Definition

-forms a green zone around colony on blood agar

-Streptococcus mutans: causes dental caries

-Streptococcus pneumoniae: causes pneumonia & meningitis in children

Term
Lactobacillus acidophilus
Definition

-used in food production

- yogurt

Term
Enterococcus
Definition

gram positive

live in GI tract, mouth & vagina

causes UTIs & wound infections

frequently cause nosocomial infections

Term
Listeria monocytogenes
Definition

grows in soft cheeses & deli meats

withstands refrigeration

should not be eated by pregnant women

can cause stillbirth

Term
Mycoplasma pneumoniae
Definition

-lack a cell wall

-require a media with horse serum and yeast extract to grow in lab

-colonies have a "fried egg" appearance

-treated with tetracycline

-causes pneumonia

Term
Mycobacterium
Definition

-resist gram stain because they have waxy cells

-cells have mycolic acid

-require acid fast stain (carbolfuchsin)

M. tuberculosis - tuberculosis

M. leprae -leprosy

Term
Corynebacterium diphtheriae
Definition

-morphology: palisades pattern

-gram positive rods

-has metachromatic granules

-closes off throat with membrane

Term
Propionibacterium acnes
Definition

-some causes of acne

-gram positive rods

-treated with tetracycline

Term
Gardnerella vaginalis
Definition

-gram variable

-causes vaginitis

Term

Chlamydiae

-Chlamydia trachomatis

Definition


-gram negative

-causes nongonococcal urethritis

-most common STD!!!

Term
Spirochaetes
Definition

coiled gram negative

move using axial filaments

Treponema pallidum - syphilis

Borrelia spp. - Lyme disease

Term
Bacteroides
Definition

gram negative anaerobes

live in the intestines

cause wound infections & peritonitis

Term
Fusobacterium
Definition

spindle shaped

live in the mouth

can cause dental abscesses

Term
Yersinia pestis
Definition

-carried by rats and fleas in the Southwest

-causes plague


Bubonic - infects lymph system, forms bubos

Septicimic - bacteria live in the blood

Pneumonic - infects lungs - 100% fatal

 

-weapon of bioterror

Term
Ricksettia prowozekii
Definition

gram negative rods

- spread by lice

- typhus (fever & rash)


Term
Ricksettia typhi 
Definition

gram negative rods

- spread by fleas

- murine typhus


Term
Ricksettia rickettsii
Definition

gram negative rods

 - spread by ticks

- Rocky Mountain Spotted Fever

Term
Nesseria gonorrheae
Definition

gram negative diplococci

normal flora of mucus membranes

 

 - gonorrhea

 

*has protein Opa that binds to CD4 lymphocytes and prevents the production of memory cells and immunity

Term
Nesseria meninginitidis
Definition

gram negative diplococci

normal flora of mucus membranes

 

- meningitis (usually in adults)

Term
Vibrio cholera 
Definition

slightly curved gram negative rods

found in salt or brackish water

- cholera

- very watery stools with intestinal mucus

- "rice water" stools

- dehydration & death


Term
Vibrio parahemoliticus
Definition

slightly curved gram negative rods

found in salt or brackish water

 - gastroenteritis from raw oysters, shrimp, and crabs

Term
Clostridium tetani
Definition

-spore forming anaerobes

-spores can live in the soil for years

 

tetanus (lockjaw)


Term
Clostridium botulinum 
Definition

 

-spore forming anaerobes

-spores can live in the soil for years

 

- botulism


 

Term
Clostridium perfringens
Definition

 

-spore forming anaerobes

-spores can live in the soil for years

 

 

 - gas gangrene


 

Term
Clostridium difficil
Definition

 

-spore forming anaerobes

-spores can live in the soil for years

 

- antibiotic resistant, normal intestinal flora, when antibiotics kill all good flora it takes over, often a nosocomial infection

Term
Bacillus cereus 
Definition

gram positive rods

food poisoning


Term
Streptococcus mutans
Definition

-forms a green zone around colony on blood agar

- causes dental caries

 

Term
Streptococcus pneumoniae
Definition

-forms a green zone around colony on blood agar

 

-causes pneumonia & meningitis in children

Term
Microbacterium tuberculosis 
Definition

-resist gram stain because they have waxy cells

-cells have mycolic acid

-require acid fast stain (carbolfuchsin)

- tuberculosis


Term
Microbacterium leprae
Definition

-resist gram stain because they have waxy cells

-cells have mycolic acid

-require acid fast stain (carbolfuchsin)

 -leprosy

Term
Treponema pallidum
Definition

coiled gram negative

move using axial filaments

 - syphilis


Term
Borrelia spp.
Definition

coiled gram negative

move using axial filaments

 - Lyme disease

Term
Histoplasma capsulatum
Definition

Histoplasmosis

lung disease that can become systemic

found in the Mississippi River Valley

Term
Coccidioides immitus
Definition

Coccidioidomycosis

lung/systemic infection

found in the Southwest

Term
Rhizopus
Definition

-black bread mold

-opportuistic systemic mycosis

(opportunistic - when immune system is compromised)

Term
Mucor
Definition

-opportunistic systemic mycosis

(opportunistic - when immune system is compromised)

Term
common culprits of dermatomycoses
Definition

Trichophyton

Microsporum

Epidermophyton

Term
Algae - Alexandrium
Definition

-causes paralytic shellfish poisoning

-humans can get PSP by eating mollusks harvested during a red tide

-causes neurological systems

-lives in the ocean

Term
protozoa - Trichomonas vaginalis
Definition

-has an undulating membrane

-STD

-causes trichomoniasis of the vagina or male urethra

Term
protozoa - Giardia lambia
Definition

-intestinal parasite

-diarrhea

-forms cysts

-ID by cysts in feces

Term
protozoa - Entamoeba histolytica
Definition

-very common worldwide

-forms cysts

-causes diarrhea

Term
protozoa - Plasmodium
Definition

-causes malaria

-4 species, infect liver & red cells 

-fevers come in waves with multiples of 25 hrs between them

-transmitted by the Anopheles mosquito

-mosquito is the definitive host, sexual reproduction takes place here

-humans are intermediate hosts where fission occurs

Term
protozoa - species of Plasmodium
Definition

P. falciparum

P. vivax

P. ovale

P. malariae

 

Term
protozoa - Babesia
Definition

-transmitted by the Ixodes scapularis tick

-causes babesiosis

-anemia

Term
protozoa - Balantidium coli
Definition

-have cilia

-causes severe dysentery

Term
Paragonimus westermani
Definition
trematode (fluke) that infects the lungs worldwide
Term
Schistosoma spp.
Definition
trematode (fluke) that infects the blood worldwide
Term
Taenia saginata
Definition

-beef tapeworm

-humans are the definitive host

-can grow up to 6 meters

-we excrete mature proglottids

-form cysticerci in beef muscle

 

Term
Taenia solium
Definition

-pork tapeworm

-humans are the definitive host

-from undercooked pork

-found in Latin America, Asia, Africa

-in the US pigs do not harbor cysts

-in US transmission is from person to person when we shed the eggs

-then we are the intermediate hosts and cysts can form

-cysticercosis - can infect the brain

Term
Echinococcus granulosus
Definition

-tapeworm

-humans are the intermediate host (harbor the cysts)

-a few mm long in the definite hosts, dogs & coyotes

-sheep & deer can be intermediate hosts too

-form hydatid cysts in our liver, lungs, or brain

-cysts may contain up to 4 liters of fluid

Term
Enterobius vermicularis
Definition

-roundworm

-pin worm

-eggs are infective

-entire life cycle is in humans

-diagnosed with cellophane tape on the anus in the morning

Term
Ascaris lumbricoides
Definition

-roundworm

-eggs are infective

-infects >1 billion people

-worm lives in small intestines

-eggs hatch

-larvae enter the blood and go to the lungs where they are coughed up and swallowed

Term
Necator americanus
Definition

-roundworm

-hookworm

-larva are infective

-larva live in soil and penetrate the soles of feet

-travels in blood to the lungs

-coughed up and swallowed

-hookworm lives in intestines

Term
Parvovirus
Definition

Fifth disease - Erythema infectiosum

mild flu-like symptoms with a "slapped cheek" rash

Term
Papillomavirus
Definition
warts, cervical cancer
Term
Variola
Definition
smallpox
Term
Varicella
Definition

Chickenpox

can become latent - shingles

Term
Herpes Simplex
Definition

(can become latent)

HSV-1: fever blisters

HSV-2: genital herpes

Term
Rubeola
Definition
measles
Term
Rubella
Definition
German measles
Term
Rhinovirus
Definition
common cold
Term
Hepatitis
Definition

Inflammation of the liver

Subspecies A,B,C,D,E,F

Term
Hantavirus
Definition

from rodents

Hantavirus pulmonary syndrome

Often lethal

Term
prions - diseases
Definition

mad cow disease

Crutzfeldt-Jacob Disease (CJD)

Kuru - causes trembling, death, from eating human brain

scrapie - a fatal degenerative disease of the central nervous system of sheep & goats

fatal familial insomnia

Gerstmann-Straussler-Scheinker Syndrome - inherited progressive dementia

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