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pathogenic bacteria
pathogenic bacteria
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Microbiology
Undergraduate 2
05/17/2010

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Term

Staphlococcus aures

A.Morphology

B.Cultural characteristics

Definition

A."grape"like gram positive spheres

B.grow on simple media,yellow pigment,

can tolerate high salt,and catalase positive

Term
Staphylococcus aures virulance factors
Definition

Protein A which binds to wrong end of ab,

and staph has a capsule

Term
Staphylococcus aures enzymes
Definition

A.coagulase

B.Hyaluronidase

C.Staphylokinase

D.Lipase

E.Beta-lactamase

Term
Staphylococcus aures toxins
Definition

A.exfoliatoxins(skin slough)

B.Hemolysisn(rbc lysis)

C.pyrogenic toxin (fever)

D.Tokic shock syndrome

E.Enterotoxins(vegas nerve)

Term
Staphylococcus aures infections
Definition

A.pimples,boils,carbuncles,urinary tract,impentigo,and scaled skin

B.Systemic

C.Bacteremia(in blood)

D.Endocarditis(Heart lining, valves)

E.Pneumonia

F.Osteomyelitis

Term

Streptococcus pyogenes

A.morphology

B.cultural characteristics

Definition

A.spherical,found as diplococci,gram positive,

and catalase negative

B.Require complex media

Term

Streptococcus pyrogenes virulance

A.protein

B.capsule

Definition

A.protein M (stops compliment fixation

B.Made of hyaluronic acid(same as ours)

Term

Streptococcus pyogenes virulence

A.Toxins

B.Enzymes

Definition

A.pyrogenic toxin(scarlet fever),

Streptolysin(lysis of rbc,wbc,platelets)

B.Streptokinase(breaks clot)

Term
Streptococcus pyogenes diseases
Definition

A.Pharyngitis(strep throat)

B.Scarlet Fever

C.Pyoderma(puss filled lesions)

D.Erysipeals(in lymph nodes)

E.Necrotizing Fasciits(flesh eating bacteria)

F.Rheumatic fever(autoimmune,attacks heart valves)

G.Glomerulonephritis(type III hyper,kidney damage

 

 

 

 

 

 

 

 

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Term

Streptococcus pneumoniae virulance

A.capsule

B.toxins

Definition

A.capsular polysacchsride(antphagocytic)

B.Pneumolysin

Term
Streptococcus pneumoniae disease
Definition

A.leading cause of bacterial pnuemonia

B.Sinusitis(sinus infection with puss)

C.Otitis media(middle ear with puss)

D.Bacteremia(in blood)

E.Endocarditis(heart lining

F.Pnuemococcal meningitis(high rate of death)

Term
Streptococcus agalatiae pathology
Definition
Babies get it coming down the birth canal
Term
Streptococcus agalactiae disease
Definition

Newborns can get pnuemonia,meningitis, blindness,deafness,mental retardation

mothers can get childbirth fever

Term
Viridians Streptococcus disease
Definition
Dental cavities,plaque
Term
Streptococcus Mutans group disease
Definition
Produce organic acids that cause tooth decay
Term
Bacillus Anthracis cultural characteristics
Definition
Aerobic to faculative anaerobic, endospore former
Term
Bacillus anthracis disease
Definition

A.Pulmonary anthrax

             (wool sorters disease,inflammation of

tissue seperating lungs)

B.Cutaneous Anthrax

(causes malignant pustule,can become systemic,death)

C.Enteric anthrax(rare)

Term
Cloristidium perfringens disease
Definition

A.Gas gangrene

B.food poisoning(diarrhea and abdominal pain)

Term
All clostridium tetani morphology
Definition

A.motile

B.small

C.terminal endospores

D.obligate anaerobe

E.gram positive

Term
Clostridium tetani disease
Definition
tetanus toxin binds to ihibitory neurotransmitters,muscles cannot relax,lock jaw, you die because your diaphram cannot relax
Term
Clostridium botulinum disease
Definition

A.Food borne ingest toxin, toxin blocks muscle  contraction causes flaccid paralysis,die

B.Infant, spores are ingested bacteria starts to

grow rare cause of sids

Term

Lactobacillus

A.morphology

B.what is it used for

Definition

A.gram positive,rods,non spore former

B.used to make pickles,yogurt,saurekrout

Term

Listeria monocytogenes morphology

 

Definition

Gram positive,nonspore forming,coccobascillus

found everywhere

Term
Listeria monocytogenes pathology
Definition

affects pregnant women, newborns can cross placenta

Intracellular parasite,binds to mac or epithelial cell and induces phagocytosis, uses lysteriolysin O to break down the cell, pushes into next cell hiding from the immune system, goes to brain

Term

Mycobacterium tuberculosis

A.morphology

B.cultural characteristics

Definition

A.Acid fast,slender straight or curved rod,

thick waxy cell wall

B.Shortest generation time 300 minutes

Term

Mycobacterium tuberculosis

pathology (primary)

Definition
inhalation(only need 10),Macs in alveoli phagocytize but cannot digest bacilli,bascilli reproduce inside mac and kill it,cell mediated response calls more macs and cycle repeats,forms a tight ball called a tubercle,caseous necrosis in center this becomes a stale mate forms ghon complex(calcium deposit)
Term

Mycobacterium tuberculosis

pathology A.(secondary)B.(dissemated)

Definition

A.Mycobacterium break out of tubercle, infection now reestablished,spreads to other parts of lungs

B.carried to other parts of the body

Term

Mycobacterium tuberculosis

A.treatment

B.Epidemiology

Definition

A.Must remain on meds for six months

B.Up to one third of population infected,risk factors overcrowding and smoking,can last up to 8 months on fomites,5 percent exposed to the disease catch it,50 percent die

Term
Mycobacterium leprae cultural characteristics
Definition
Grows best at 30C,on footpads of mice, not on normal media
Term
Mycobacterium leprae disease
Definition

A.Tuberculoid Leprosy(minor skin infection)

B.Lepromatous Leprosy(the bad one)

Term
Mycobacterium avium who does it affect?
Definition
Aids patients
Term
Corynebacterium diptheriae virulence factors
Definition
Toxin-Diphtheria toxin
Term
Corynebacterium diptheriae pathology
Definition
Toxins get into cell by endocytosis,stops ribosome function killing cells
Term

Corynebacterium diphtheriae disease

A.respitory B.cutaneous C.systemic

Definition

A.severe signs and symptoms,local pain,fever,oozing of fluid,formation of the psuedomembrane

B.Psuedomembrane on the skin

C.toxins can be released causing death to heart and nerve cells leads to coma and death

Term

Neissera

A.morphology

B.cultural characteristics

Definition

A.gram negative,bean shaped cocci with fimbrae

B.Needs Thayer-Martin agar,best with 5%c02,

very susceptible to drying out

Term
Neissera gonorrhoeae pathology
Definition
sexually transmitted breaks down iga,attaches to epithelial cells and induces phagocytosis by wbc`s then carried throughout body
Term

Neisseria gonorrhoeae disease

A.men

B.women

C.infant

Definition

A.painful urination,puss discharge

B.mostly asymptomatic,attach to vagina and cervix can get to fallopian tubes causing infertility,ectopic pregnancy

C.Happens coming down birth canal,called

opthalmia neonatorum causes blindness

Term

Neissera gonorrhoeae

A.diagnosis

B.Treatment

C.immunity

Definition

A.gram negative diplococcal found in puss

B.very resiliant,cephalosporan

C.no vaccine,antigenic variability,can get repeatedly

Term
Nesseria meningitids pathology
Definition
spread on droplets,has polysacharide capsule that keeps it from being degested, carried throughout body by wbc,contains lipid A which causes fever,vasodialation,inflamation,and shock
Term
Neisseria meningitiidis disease
Definition

Flu like symptoms,convulsions,arthritis,loss of hearing,and septicemia-petechiae(skin lesions)

spread by cramped living conditions

Term
name the six types of enterobacteriaceae
Definition

A.coliform(e.coli)

B.Klebsiella

C.proteus

D.Salmonella

E.shigella

F.Yersinia

Term
What bacteria gives you really watery sometimes bloody diarreah?
Definition
E.coli
Term
E.coli pathology
Definition
oral fecal route,pili bind to epithelial cells,can produce enterotoxins in the intestines,uti normal flora in wrong place
Term
What are the four strains of E.coli
Definition

A.Enterotoxigenic (diarrhea)

B.Enteropathogenic(comes together because of pili)

C.Enteroinvasive(invades intestinal cells like shigella)

D.Enterohemorrhagic(strain #0157:h7 causes

hemolytic uremic syndrome)

Term
Klebsiella pneumoniae what and who
Definition

causes pnuemonia(destroys alveoli)

Alcoholics and aids

Term
What are the two types of salmonella
Definition
S.typhi and S.typhimurium
Term
Salmonella typhus pathology
Definition
oral fecal route, bacteria go thru the intestines to the blood, get phagocytized but not killed, carried to the spleen,liver,bone marrow,and gall bladder back to intestines then eats hole in intestines
Term
S.typhimurium pathology
Definition
causes salmonellosis,found on eggs,passes thru stomach attaches to intestines,inserts protein into cell,induces phago by intestinal cells,reproduces in cell and kills it
Term
What bacteria causes green diarrhea than turns mucusy
Definition
Salmonella typhimurium
Term
Yersina pestis disease
Definition

Bubonic plague(spread by flea bites,goes to lymph

nodes and causefever and pain untreated causes bacteremia,causes coagulation of blood and

leads to gas gangrene)

Pneumonic plague(Spread by droplets,infects the lungs)

Term
Proteus mirabilis pathology
Definition
motile bacteria that swim up cathaters creates kidney stones
Term
Shigella pathology
Definition

goes to large intestine attaches to epithelial

cells and induces phag,reproduces in cells,

invades other cells,forms abcess,

does not invade blood

Term

What bacteria causes fibrous diarrhea

with agonizing pain?

Definition
Shigella
Term
What are the two types of spirochetes?
Definition

Treponema(syphilis)

Borrelia(lyme disease)

Term

Treponema pallidum pallidum

phases

Definition

primary forms a chancre which is small painless

and red,lesions last 3-6 weeks then go away

Secondary rash all over body which does not

itch after several weeks it goes away

Latency no signs or symptoms

Tertiary stage get gummas all over tissues

found on nerve cells and in the brain

Term
Borrellia burgdorferi what and how
Definition

Lyme disease

spread by deer tick

Term
Borrellia burgdorferi phases
Definition

Phase one bulls eye rash,stiff neck,and severs fatigue

Phase two Meningitis,cardiac problems

Phase three Severe arthritis that can last for years

Term
Chlamydia Morphology
Definition
Extremely small, obligate intracellular parasites
Term
Chlamydia Life cycle
Definition

1.Elementary body attaches to host cell,get phag,

now in inclusion body

2.Inside the cell becomes a reticulate body,

reproduce by binary fission

3.Back to elementary bodies,cause cell lysis,

release elementary bodies

Term
Chlamydia psittaci disease
Definition
Inhalation of elementary bodies from birds causes a flu like disease called parrot fever
Term
Chlamydia trachomatis A,B,Ba,C disease
Definition
Spread by flies,eye disease causes blindness
Term
Chlamydia D,E,F,G,H,I,J,K disease
Definition
Sexually transmitted,Nongonococcal Urethritis,Asymptomatic in women,opthalmia neonaterum
Term

Chlamydia trachomatis L-1,L-2,L-3

disease stages

Definition

1.starts as a painless lesion that heals quickly

2.Causes the inguinal lymph nodes

to swell forms a bubo

3.Lymph nodes burst,constriction of urethra,elephantiasis,arthritis in white males

Condoms dont help

Term
Vibrio cholera pathology
Definition
Eat contaminated food,toxin gets into cells causing the secretion of electroytes,water follows,causes rice water diarrhea 20-30 times a day,lose 10 -15 liters of water a day,can cause coma and death
Term
What bacteria causes rice water diarrhea?
Definition
Vibrio Cholera
Term

Helicobacter pylori

A.morphology

B.pathogenicity

Definition

A.highly motile flagella, gram

negative,slightly helical

B.oral fecal route, from cats

Term
Heliobacter pylori disease
Definition
Formation of peptic ulcer,burrows through mucus,kills mucus producing cells,causing a weak spot
Term
Psuedomonas Aeruginosa disease
Definition
Gets into wounds of burn patients and cystic fibrouses patients,very resistant to drugs
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