Term
What are the 3 biochemical barriers? |
|
Definition
secretions, macromolecules, and normal bacteria flora |
|
|
Term
What is the term that describes when the WBCs exit the blood vessel walls? |
|
Definition
diapedesis, leukocyte extravation |
|
|
Term
The redness in inflammation is caused by? |
|
Definition
vasodialation and vasculare permeability |
|
|
Term
What causes the heat symptom of inflammation? |
|
Definition
increased blood flow due to vasidialation |
|
|
Term
What causes swelling in inflammation? |
|
Definition
extra fluid leakage from vascular permability |
|
|
Term
What are some benefits of inflammation? |
|
Definition
limit and control of tissue damage, prevents infection, initiates adaptive immunity, and initiates healing |
|
|
Term
What isolates an infection by building a wall and confining injurious agents? |
|
Definition
|
|
Term
What molecules are released during mast cell degranulation? |
|
Definition
histamine and chemotactic factors |
|
|
Term
What are synthesized during mast cell activation? |
|
Definition
leukotrienes, prostoglandins, platelet activating factor |
|
|
Term
|
Definition
causes temporary, rapid constriction of smooth muscle and dilation of the post capillary venules |
|
|
Term
Which histamine receptor promotes inflammation? |
|
Definition
|
|
Term
What are the 3 plasma protein systems? |
|
Definition
complement, clotting, kinin |
|
|
Term
What are the 4 functions of the products of the complement system? |
|
Definition
opsonization, anaphylatoxic activity, chemotaxis, cell lysis |
|
|
Term
What is the process by which a pathogen is marked for destruction? |
|
Definition
|
|
Term
What induced rapid degranulation of mast cells? |
|
Definition
anaphylotoxins in anaphylatoxic activity |
|
|
Term
What are the 4 effects of the clotting system? |
|
Definition
stops bleeding, traps infectious organisms, localizes (traps) injurious agents to the site of inflammation, and aids in repair and healing |
|
|
Term
What are both the clotting cascade and the kinin cascade activated by? |
|
Definition
|
|
Term
What is the final product of the kinin cascade? |
|
Definition
|
|
Term
What are the 4 types of inflammatory blood cells? |
|
Definition
granulocytes (neutrophils, eosinophils, basophils), monocytes, platelets, lymphocytes |
|
|
Term
How quickly do neutrophils appear at the site of inflammation? |
|
Definition
|
|
Term
What are the primary roles of neutrophils? |
|
Definition
phagocytosis, removal of debris |
|
|
Term
What products become a part of purulent exudates (pus) upon their death? |
|
Definition
|
|
Term
what attracts macrophages? |
|
Definition
chemokines released from neutrophils |
|
|
Term
What are the 2 functions of eosinophils? |
|
Definition
body's primary defense against parasites and degrades vasoactive amines (histamine)to end the inflammatory response |
|
|