Term
What recognize specific antigens? |
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Definition
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Term
What type of cells are involved in humoral immunity? |
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Definition
B cells/B lymphocytes; B cells converted to plasma cells which produce antibody |
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Term
What type of cells are involved in cell-mediated immunity? |
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Definition
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Term
What 3 ways can active (aquired) immunity occur? |
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Definition
by natural exposure to an antigen (body will produce its own antibodies), immunization, or bone marrow transplant |
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Term
Where are T cell receptors located? |
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Definition
on all types of T cells except Natural killer cells |
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Term
T cells are important in protection against what? |
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Definition
viruses, tumors, and pathogens that are resistant to killing by normal neutrophils and macrophages |
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Term
Class I MHC binds to antigens in what part of the cell? |
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Definition
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Term
On what cell is CD8 located and to what does it bind? |
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Definition
CD8 is found on the surface of a cytotoxic T cell and binds to Class I MHC |
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Term
What MHC Class is endogenous antigen processing associated with? |
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Definition
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Term
What MHC Class is exogenous antigen processing associated with? |
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Definition
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Term
On what cell is CD4 located and to what does it bind? |
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Definition
CD4 is located on helper T cells and binds to Class II MHC |
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Term
Where are Class I MHC found? |
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Definition
on ALL nucleated cells and platelets |
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Term
Where are Class II MHC found? |
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Definition
on B cells, APCs, and some epitheliel cells |
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