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Number of disease present in population (1/10,000) |
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Subjective comments made by the patient |
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Objective: measurable. Ex color change, BP , HR, RR |
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What causes the disease ( usually do not know) |
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How the disease manifests itself (usually know this) |
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What the disease is (not examination |
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The study of functional or physiologic changes in the body that result from the disease process |
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Any deviation from the normal state of health or wellness. |
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When homeostasis can't be maintained w/o intervention. |
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What is the likelihood for the Pt to handle the disease. |
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Varies with prognosis. What we do to intervene with the Pt. |
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Physical observation of the Pt. |
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The one thing about the disease that identifies that disease. Hallmark of a disease. |
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EX: Air pollution, asbestos |
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Definition
Something that you produce, ALLERGIES |
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They don't know the cause of the disease process. |
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Physician induced process. Wrong medications, chemotherapy. |
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Definition
Lack of O2. Stops aerobic respiration. |
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Definition
Lack of blood/perfusion. CO poison--> hypoxia prior to Ischemia. |
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Definition
Leads to cellular death. Burns, extreme cold |
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Antibodies attacking antibodies or self attacks self |
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Obesity-- 55% of population |
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Definition
Cellular swelling =Hydropic swelling---cells taking on Na due to poor Na/K+ pump. -Wherever salt goes |
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Definition
makes proteins, release ribosomes |
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Definition
Liver cells accumulate fat when damaged |
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Definition
Blebs -If PM is damage, the membrane bulges out |
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Definition
Cell returns to normal when stressor is absent |
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Definition
Adaptation, continual alcohol intake for years. |
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Definition
ETOHic---grows more of this to detoxify the alcohol |
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Term
Sequestration of focal injury |
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Definition
Body walls off the injured area to keep away from the rest of the body |
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Definition
Decrease in the SIZE of the cell. Ex: hormone reduction w/ aging results in breast size reduction |
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Definition
Enlarging of the cell. L ventricular hypertrophy. Not an increase in the number of the cells |
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Definition
Decrease in the number of cells |
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Increased number of cells. Ex: callus |
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Definition
Change from one cell type to another type. Ex: Smoking-> trachea turns into stratified squamous instead of pseudo stratified. |
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Definition
Cell looks and acts ABNORMAL, but not CA... yet |
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Definition
Lack of growth, did NOT form the organ or tissue such as someone that is born with out vertebrae---spina bifid a |
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Definition
Independent growth of cells. Forms tumor. |
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CNS, PNS, cariomyocytes. So post CVA or MI, do not regrow neurons or muscle cells respectively. |
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Definition
Skeletal muscle, kidney, lung, liver. |
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Constantly turned over. Examples: skin, lining of GI Tract, blood. |
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swell and form large deposits inside of them with protein or Ca+ inside them. The powerhouse stops working--aerobic respiration stops. |
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Blebs are sublethal. If dead, then becomes permeable to everything. |
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Membrane breaks down and digestive enzymes release w in the cell. |
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nucleus fragments into pieces. |
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Process of removal of dead tissue. Lysosomes start the process and macrophages finish. |
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Usually found following ischemia, loss of normal organelle structure, Ischemia or infarction, |
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Accumulation of PMN's (pus), usually found with bacterial infection. |
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Usually found with pancreatic disease that leaks lipases. Ex: acute pancreatitis or abdominal trauma. |
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(cheese) mostly found with TB; due to resemblances of cottage cheese. CXR---Ca+ deposits that is what is left after damage. Once TB, always TB |
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Definition
that is found in the walls of blood vessels with insulation of plasma proteins. Fibrin leaks into the interstitial area. |
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Definition
Caused by infection of ischemic tissue by clostridial perfringens (anaerobic microorganism). This infective agent contains many spreading factors-- myotoxin, hemolysins, & phospholipases-- that rapidly can lead to amputation or death. Hemoglobin turns black= eschar. |
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Definition
viewed as a continuum. Wellness on one end and illness on the other end. |
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Definition
Dynamic process that varies with changes in interactions between an individual and the internal & external environments. |
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Definition
has a relatively rapid onset & short duration |
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Definition
describes a time course that is between acute & chronic |
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Definition
results permanent impairment or disability or need for special rehabilitation and or long term medical management |
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Definition
removing or reducing the disease risk factors |
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Definition
promote early detection of disease & employ preventive measures to avoid further complications. |
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aimed at limiting the impact of the established disease. Involves rehab and may end when no further healing is expected. |
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Definition
cardiovascular dz, CA, DM |
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an aging pigment lipid granule, found especially in neurons & cardiac myocyte, is suspected to cause pressure on the cell nucleus and interfere with cellular function |
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Term
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Definition
Nerve Conduction velocity |
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Term
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Definition
Glomerular Filtration Rate |
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Definition
Cells that can't regenerate such as cardiomyocytes become worn out. |
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Definition
the chemical nature & wide presence of free radicals causing DNA damage & cellular oxidative stress with aging. |
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Term
Telomere aging clock theory |
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Definition
end of the chromosomes that acts as a clock signaling the onset of cell senescence (telomere may be used as CA marker) |
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