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about 40% of body weight; comprises all the fluid within cells |
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about 15% of body weight, the space between cells and outside blood vessels |
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about 5% of body weight; blood plasma |
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the movement of fluid back and forth across the capillary wall (Starling forces) |
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(blood pressure) facilitates the outward movement of water from the capillary to the interstitial space |
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(plasma pressure); osmotically attracts water from the interstitial spaces into the capillaries |
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usually limited to a site of trauma, such as a sprained finger. |
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manifested by a more uniform distribution of fluid in interstitial spaces. |
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Renin-angiotensis-aldosterone system- a mechanism by which sodium and water levels are regulated in teh body, including the release of renin,conversion of angiotensinogen into angiotensisI, conversion of angiotensis I into angiotensis II and the release of aldosterone and its actions on the kidney that increase water and sodium reabsorption |
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a mineralcorticoid synthesized and secreted from the adrenal cortex |
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occurs when sodium levels exceed 145 mEq/L; causes intracellular dehydration |
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develops when the serum sodium concentration falls below 135 mEq/L. Occurs frequently in hospitalized elderly. Caused by vomiting, diarrhea, diuretics |
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low potassium levels. Caused by reduced intake of potassium, increased entry of potassium into sells. Can occur in alcoholism and anorexia nervosa |
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elevation of ECF potassium concentration above 5.5 mEq/L. Rare. Addison disease. |
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serum concentrations > 10-12 mg/dl; causes such as hyperparathyroidism, bone metastases, calcium resorption from breast, prostate, renal, and cervical cancer |
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serum calcium concentration <8.5 mg/dl; related to intestinal absorption, deposition of ionized calcium into bone or soft tissue; nutritional deficiencies in inadequate sources of leafy greens and dairy |
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occurs in response to the acid-base status. Can absorb excessive hydrogen ions or hydroxyl ions and prevent a significant change in pH |
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the concentrations of non-carbonic acids increase or bicarbonate is lost from extracellular fluid or cannot be regenerated by the kidney |
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when excessive loss of metabolic acid occurs, bicarbonate concentration increases. |
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