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patho test 2
test two
13
Nursing
Undergraduate 1
02/12/2012

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Term
pro inflammatory cytokines include:
Definition
histamine prostaglandins and leukotrienes
Term
inflammatory cytokines can be:
Definition
pro or anti inflammatory
Term
histamine
Definition
-high concentrations in platelets basophils and mast cells
- ^ permeability
one of the first mediators of an inflammatory response
H1-upper respiratory
H2-GI
-effects depend on density and affinity of receptors on target cell and identity of target cells
Term
cytokines
Definition
effect other cells
intracellular messengers
instruct cells to alter proliferation differentiation secretion or activity
100 different ones
pro or anti inflammatory
classified as interleukins or interferons
Term
Monocytes are in the _______.
Macrophages are in the ________.
Definition
Blood.
Tissues.
Term
1st line of defense
Definition
Innate. Nonspecific. no memory.
Ex: anatomical barriers
effective NOW
Term
2nd line of defense
Definition
inflammatory response and non-specific phagocytes. NO memory. antigen independent.
Neutrophils, monocytes/macrophages, mast cells, basophils, eosinophils
works NOW
Term
3rd line of defense
Definition
specific acquired. anditgen specific/ dependent. MEMORY. accelerated secondary response. b-cells/t-cells. days to develop.
Term
innate immune defense
Definition
no memory. same every time.
Term
signs of inflammation
Definition
heat swelling pain redness and loss of function
Term
what does inflammation do?
Definition
capture and remove injurious agents from inflammatory site, wall and confine if you can’t remove, stimulate and enhance the immune system, and promote healing.
Term
inflammation is...
Definition
non-specific, immediate
Term
immunity
Definition
antigen specific, has memory, takes days to develop
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