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PATHO NERVOUS SYSTEM CHAPTER 14
NURSING
124
Nursing
Not Applicable
12/04/2023

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Term
What area does CSF circulate around the brain and spinal cord
Definition
Subarachnoid space
Term
Where is the language center located
Definition
Left hemisphere
Term
Definition of aphasia
Definition
Unable to comprehend or express language correctly
Term
What is an early manifestation of increasing ICP's
Definition
Decrease level of consciousness
Term
Cushing's reflex or triad includes what
Definition
Increase pulse pressure, bradycardia, and irregular respirations
Term
What part of the brain is being affected with increased ICP and projectile vomiting
Definition
Emetic center in the medulla
Term
What is the main function of the limbic system
Definition
Determines emotional responses
Term
The common type of tumors that adults usually have arising in the CNS
Definition
Gliomas
Term
What affect will a brain abscess have on the cardiovascular system
Definition
Slower heart rate and systemic vasoconstriction
Term
What color should normal CSF look like
Definition
clear and colorless
Term
Where do secondary brain tumors normally metastasize to
Definition
Breast and lungs
Term
Primary brain tumors rarely metastasize outside of the central nervous system
Definition
True - brain tumors rarely metastasize outside of the central nervous system
Term
A TIA can be an indicator for what potential complication
Definition
CVA
Term
What is the most likely source of an embolus that causes a CVA
Definition
Common carotid artery
Term
Bacterial meningitis can cause swelling and purulent exudate where
Definition
Pia, arachnoid and surface of the entire brain
Term
What clinical manifestations will you see with acute bacterial meningitis
Definition
Nuchal rigidity, photophobia, and a severe headache
Term
What is the cause of St. Louis encephalitis
Definition
Ticks and mosquitos
Term
What is the patho of Guillain-Barre' syndrome
Definition
Demyelination and inflammation of peripheral nerves
Term
Where does an epidural hematoma occur
Definition
Dura mater and the skull
Term
What are the clinical manifestations of autonomic dysreflexia when a person has a cervical spine injury
Definition
Bradycardia and sudden increase in blood pressure
Term
Through what area does the cerebrospinal fluid circulate around the brain and spinal cord
Definition
In the subarachnoid space
Term
Which of the following is the usual location of language centers?
Definition
- Left hemisphere
Term
What would be the effect of damage to the auditory association area in the left hemisphere?
Definition
Inability to understand what is heard
Term
Which of the following applies to the corticospinal tract?
Definition
It is a pyramidal tract for efferent impulses.
Term
What is a major function of the limbic system?
Definition
Determines emotional responses
Term
Where are 1-adrenergic receptors located?
Definition
Cardiac muscle
Term
What does a vegetative state refer to?
Definition
Loss of awareness and intellectual function but continued brainstem function
Term
Which of the following conditions is NOT part of the criteria for a declaration of "brain death"?
Definition
Presence of any head injury
Term
What is an early indicator of increased intracranial pressure?
Definition
Decreasing responsiveness
Term
What is the rationale for vomiting in a patient who has increased intracranial pressure?
Definition
Pressure on the emetic center in the medulla
Term
What is the typical change in blood pressure in a patient who has increased intracranial pressure?
Definition
Increasing pulse pressure
Term
The largest category of primary malignant brain tumors that arise from cells in the central nervous system (CNS) are called:
Definition
Gliomas.
Term
Which of the following causes papilledema?
Definition
Increased pressure of cerebrospinal fluid (CSF) at the optic disc
Term
What is the effect of an enlarging brain abscess on cardiovascular activity?
Definition
Systemic vasoconstriction and slower heart rate
Term
As intracranial pressure rises, the pupil of the eye, ipsilateral to the lesion, becomes dilated and unresponsive to light because of pressure on the:
Definition
peripheral nervous system (PNS) fibers in cranial nerve III.
Term
Which of the following characteristics indicates that the CSF is normal?
Definition
- Clear and colorless fluid
Term
Which of the following statements is TRUE about malignant brain tumors?
Definition
Primary brain tumors rarely metastasize outside the CNS.
Term
Secondary brain tumors usually arise from:
Definition
- metastasized breast or lung tumors.
Term
Why are focal or generalized seizures sometimes an early indication of a brain tumor?
Definition
Surrounding inflammation stimulates neurons to discharge spontaneously.
Term
Which of the following is a TRUE statement about transient ischemic attacks (TIAs)?
Definition
They can warn of potential cerebrovascular accidents.
Term
What is the probable source of an embolus causing a cerebrovascular accident (CVA)?
Definition
Common carotid artery
Term
Collateral circulation is most likely to be present when a CVA results from:
Definition
atherosclerosis.
Term
All of the following apply to CVA EXCEPT:
Definition
maximum necrosis and infarction develop within several hours of onset.
Term
Signs and symptoms of a stroke depend upon:
Definition
location of obstruction, size of artery, and area affected.
Term
In the weeks following CVA, why might some neurological function return?
Definition
1. Presence of collateral circulation

2. Immediate therapy to dissolve thrombi and maintain perfusion

3. Reduced inflammation in the area

4. Development of alternative neuronal pathways
Term
Which of the following statements about berry aneurysms in the brain is NOT true?
Definition
CSF remains free of blood.
Term
In a case of bacterial meningitis, where does swelling and purulent exudate form?
Definition
In the pia mater, arachnoid, and surface of the entire brain
Term
What are significant signs of acute bacterial meningitis?
Definition
Severe headache, nuchal rigidity, and photophobia
Term
In many types of encephalitis, such as St. Louis encephalitis, how are the viruses transmitted?
Definition
Mosquito and tick bites
Term
All of the following apply to tetanus infection EXCEPT:
Definition
signs of fever, vomiting, stiff neck, and paralysis.
Term
In cases of Guillain-Barré syndrome, what does the pathophysiology include?
Definition
Inflammation and demyelination of peripheral nerves, leading to ascending paralysis
Term
How does a depressed skull fracture cause brain damage?
Definition
A section of skull bone is displaced below the level of the skull, causing pressure on the brain.
Term
Following a head injury, what is the most likely cause of secondary damage
Definition
Hematoma or infection
Term
An epidural hematoma is located between the:
Definition
- dura mater and the skull.
Term
What does the term otorrhea mean?
Definition
CSF leaking from the ear.
Term
Vertebral fractures are classified as:
Definition
simple, compression, wedge, dislocation.
Term
Following a spinal injury at C5, what is the expected effect during the period of spinal shock?
Definition
Possible periods of apnea
Term
Following an injury at L2 to L3, what would indicate recovery from spinal shock?
Definition
Spastic paraplegia
Term
What are the signs of autonomic dysreflexia in a person with cervical spinal injury?
Definition
Sudden marked increase in blood pressure with bradycardia
Term
Expressive aphasia is most likely to result from damage to:
Definition
the left frontal lobe.
Term
What is the usual result of damage to the right occipital lobe?
Definition
Loss of left visual field
Term
How does the heart rate change as intracranial pressure increases?
Definition
Rate decreases
Term
Which statement best describes herniation resulting from increased intracranial pressure?
Definition
Displacement of brain tissue downward toward the spinal cord
Term
Which type of cerebrovascular accident (CVA) has the poorest prognosis?
Definition
Hemorrhagic CVA
Term
Which of the following factors predispose(s) an individual to a CVA?
Definition
1. Hypertension

2. Smoking cigarettes

3. History of coronary artery disease

4. Diabetes mellitus
Term
What are the significant early signs of a ruptured cerebral aneurysm?
Definition
- Severe headache, nuchal rigidity, and photophobia
Term
The stroke scale used to rapidly diagnose a stroke includes:
Definition
capacity for speech, level of consciousness, motor skills, eye movements.
Term
With regard to meningitis, choose the correct combination of microbe and the age group commonly affected.
Definition
N. meningitides: children and youth
Term
Which of the following statements applies to a lumbar puncture?
Definition
It is usually performed at L3-L4.
Term
Which signs are indicative of post-polio syndrome?
Definition
Progressive fatigue and weakness
Term
Which of the following does NOT apply to Reye's syndrome?
Definition
There is no permanent damage in the body.
Term
Which type of fracture typically occurs at the base of the skull?
Definition
Basilar
Term
The primary reason for seizures frequently occurring with head injuries is:
Definition
presence of blood irritates the neurons.
Term
Brain injury where the brain is injured when it bounces off of the skull due to sudden acceleration or deceleration is referred to as a/an:
Definition
contrecoup injury
Term
The rabies virus is usually transmitted by:
Definition
bites from infected animals.
Term
Common manifestations of rabies infection include:
Definition
headache, foaming at the mouth, and difficulty swallowing.
Term
Which statement is TRUE about tetanus infection?
Definition
Infection usually develops in deep puncture wounds.
Term
Which of the following impairments results from infection by the polio virus?
Definition
Loss of function of motor neurons of the spinal cord and medulla
Term
Herpes zoster can be identified by a typical:
Definition
unilateral rash and pain along a cranial nerve or dermatome.
Term
Which of the following conditions is marked by focal signs?
Definition
Brain abscess
Term
Typical signs of a TIA include:
Definition
transient muscle weakness in a hand or leg.
Term
In cases of noncommunicating hydrocephalus, why does excess cerebrospinal fluid (CSF) accumulate?
Definition
An obstruction is present in the aqueduct of Sylvius or other channel.
Term
All of the following are typical signs of hydrocephalus in the neonate EXCEPT:
Definition
vomiting, headache, and paralysis.
Term
The best description of a myelomeningocele is:
Definition
herniation of the meninges, CSF, and spinal cord or nerves through a vertebral defect.
Term
How is the presence of spina bifida diagnosed?
Definition
Prenatally by ultrasound or detection of alpha-fetoprotein (AFP) in maternal blood or amniotic fluid
Term
What characteristic is common to all individuals with cerebral palsy?
Definition
Some degree of motor disability
Term
Which of the following applies to cerebral palsy?
Definition
Nonprogressive brain damage to the fetus or neonate
Term
Which of the following is characteristic of generalized seizures?
Definition
The uncontrolled discharge of neurons in both hemispheres
Term
From the following, choose the two events (in correct sequence) that immediately follow the aura during a tonic-clonic event:
Definition
Loss of consciousness, then the tonic stage
Term
What does the clonic stage of a seizure consist of?
Definition
Alternating contractions and relaxation of skeletal muscles
Term
How would a seizure consisting of bizarre or inappropriate activity be classified?
Definition
Psychomotor seizure
Term
Which of the following is characteristic of multiple sclerosis?
Definition
Remissions and exacerbations
Term
Which statement does NOT apply to the pathophysiology of multiple sclerosis?
Definition
Progressive random degeneration of peripheral nerves
Term
Which of the following are common early signs of multiple sclerosis?
Definition
Areas of numbness, weakness in the legs, visual problems
Term
Which of the following applies to Parkinson's disease?
Definition
Usually develops in men and women over 60 years of age.
Term
What is the pathophysiological change in Parkinson's disease?
Definition
Degeneration of the basal nuclei with a deficit of dopamine
Term
Which of the following are common early manifestations of Parkinson's disease?
Definition
Tremors at rest in the hands and repetitive motion of the hands
Term
In which type of neuron is progressive degeneration occurring with amyotrophic lateral sclerosis (ALS)?
Definition
Upper and lower motor neurons
Term
Which of the following statements does NOT apply to myasthenia gravis?
Definition
Dementia develops in the later stage.
Term
Which statement applies to Huntington's disease?
Definition
It presents with choreiform movements in the upper body and decreased ability to concentrate.
Term
What are the characteristic changes in the brain of a patient with Alzheimer's disease?
Definition
Cortical atrophy with plaques and neurofibrillary tangles, impairing conduction
Term
Which disease is associated with excessive dopamine secretion, decreased gray matter in the temporal lobes, and abnormal hippocampal cells in the brain?
Definition
Schizophrenia
Term
In which disorders do biochemical abnormalities involving the neurotransmitters in the brain occur?
Definition
- Huntington's disease
Term
Which of the following are typical characteristics associated with schizophrenia?
Definition
Disorganized thought processes, short attention span, delusions
Term
What is the typical initial effect of a herniated intervertebral disc at the L4 to L5 level?
Definition
Lower back pain radiating down the leg
Term
What causes a herniated intervertebral disc?
Definition
A protrusion of the nucleus pulposus through the annulus fibrosis
Term
Which of the following dietary supplements has reduced the incidence of spina bifida in recent years?
Definition
Folic acid
Term
Which of the following is the most common cause of brain damage in children with cerebral palsy?
Definition
Hypoxia
Term
The ataxic form of cerebral palsy results from damage to the:
Definition
cerebellum.
Term
Which of the following is used to confirm the diagnosis of, and classify, seizures?
Definition
Electroencephalogram
Term
Which statement does NOT apply to status epilepticus?
Definition
Person does not lose consciousness during seizure.
Term
Which type of seizure commonly occurs in children?
Definition
Absence
Term
All of the following may precipitate a seizure EXCEPT:
Definition
hypoventilation.
Term
Which of the following is NOT a typical effect of advanced Parkinson's disease?
Definition
Loss of vision
Term
Which of the following is a typical early sign of amyotrophic lateral sclerosis (ALS)?
Definition
Weakness and muscle atrophy in upper limbs
Term
Which of the following classes of drugs may provide temporary improvement in cases of myasthenia gravis?
Definition
Anticholinesterase agents
Term
Which of the following are typical early signs of Alzheimer's disease?
Definition
Behavioral changes

Reduced ability to reason and problem solve
Term
Which of the following is NOT considered to be a common contributing factor to AIDS dementia?
Definition
Development of arteriosclerosis
Term
Communicating hydrocephalus causes increased intracranial pressure because of:
Definition
failure of the subarachnoid to absorb CSF.
Term
Failure of the spinous processes to fuse, but without herniation of the meninges, is called:
Definition
spina bifida occulta.
Term
Which statement is TRUE about amyotrophic lateral sclerosis (ALS)?
Definition
Cognitive function remains normal.
Term
Creutzfeldt-Jakob disease is caused by:
Definition
infection in the brain by a prion.
Term
Huntington's disease is diagnosed by:
Definition
DNA analysis.
Term
Which statement is TRUE about depression?
Definition
It is classified as a mood disorder.
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