Term
| Physiologic effects of stress discovered by Dr. Hans Selye |
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Definition
Enlargment of adrenal gland
Atropy of thymus gland
Bleeding ulcers of stomach and duodenal lining |
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Term
| 3 stages of the general adaptation syndrome |
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Definition
Alarm Stage
Stage of resistance or adaptation
Stage of exhaustion |
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Term
| Characteristics of alarm stage |
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Definition
Arousal of body's defenses
Direct stimulation of Sympathetic NS - fight or flight |
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Term
| Characteristics of resistance/adaptation stage |
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Definition
| mobilization contributes to fight or flight. we either react & adjust or fight it off. |
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Term
| Characteristics of the stage of exhaustion. |
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Definition
| Continued stress causes breakdown of compensatory mechanisms, acquired adaptations and homeostasis. Marks onset of diseases of adaptation. |
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Term
| A conditional stress response is... |
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Definition
associating a stimuli with danger
an example is PTSD |
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Term
| An acute release of catecholemines results in? |
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Definition
| Increase in T cells & NK cells |
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Term
| Chronic release of catecholemines is? |
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Definition
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Term
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Definition
o Constricts peripheral BVs
o Dilates pupils
o Chill bumps
o Sweat in palms & axilla |
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Term
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Definition
Gluconeogenesis
Glycogenolysis
Dialates vessels in skeletal muscle
Increases CO |
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Term
| Cortisol is released from the __ __ and Corticotropin-releasing hormone is released from the __? |
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Definition
| Cortisol is released from the adrenal gland and Corticotropin-releasing hormone is released from the hypothalamus |
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Term
| Effects of Th1 to Th2 shift? |
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Definition
| More allergic responses, infections, temporary worsening of autoimmune conditions (like arthritis) |
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Term
| Natural barriers & inflammatory response are part of what type of immunity? |
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Definition
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Term
| A person is exposed to worms, what biochemical barrier is going to be produced in the GI tract? |
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Definition
| Resistin-like molecule beta |
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Term
| In the vascular response of inflammation ___ constrict while ___ dilate? |
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Definition
| In the vascular response of inflammation arterioles at the site constrict while blood vessels dilate |
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Term
| Histamine is released from ___ cells where they are stored in ___? |
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Definition
| Histamine is released from mast cells where they are stored in granules |
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Term
| True or false? Histamine actions are the same as the initial inflammatory response? |
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Definition
False! it's the opposite.
o arteriolar dilation
o constricts large arteries
o increases vascular permeability |
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Term
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Definition
smooth muscle contraction
vasodilation
increased vascular permeability |
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Term
| C3a, C4a, C5a are anaphylatoxins that induce? |
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Definition
| mast cell degranulation & release of histamine |
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Term
| Opsonin - definition & example |
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Definition
molecules that "tag" microorganisms for destruction by cells of the inflammatory system
C3b |
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