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what is the cytoskeleton function? |
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facilitated diffusion of a nonlipid soluble through a membrane needs a? |
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Definition
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countertransport the 2nd active transport? |
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Definition
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increased level of messengers would indicate what receptors? |
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Definition
down regulation.. so few receptors |
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what activates the 2nd messeneger? |
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Definition
g protein linked receptor |
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ligand/protein open what channels? |
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Definition
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what is anaerobic metabloism? |
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Definition
small amt of ATP
pyrvic acid biproduct |
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what happens when threshold potential is met? |
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Definition
acttion pot. will happen not stopping at this point
K+ out of cell/Na in cell.. cell positive
depolarization responds by contractin |
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Definition
checkpoint in cell division |
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Definition
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what is a characteristic of a malignant tumor? |
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Definition
poorly differentated cell |
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characteristic of cancer cell |
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Definition
undiffereinatated cell ( don't differientate) |
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toxicities attack the GI tract why? |
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Definition
b/c rapid dividing cellls |
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how is anaphylactic different from any other type 1 hypersensitivity? |
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Definition
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mast cell regradation release histamines that cause? |
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Definition
vasoconstriction, bronchoconstrictions,
SOB, decrease BP |
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what is a type II hypersensitivity? |
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Definition
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systemic lupus errythema (SLE) is a type III hypersens. what do you expect to find? |
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Definition
deposit in tissue and damage tissue |
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what cells do HIV affect? |
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Definition
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when can HIV be spread? AT what time? |
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Definition
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when managing AIDs what do you want to look at at? |
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Definition
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neutrophils `are 1st responders they relsease proteases prolytic enzymes what do they do? |
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Definition
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Definition
APC (antigen presenting complex) holds out so other recognizes it or phagoctyes engulfs invader |
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what is the last step of the complement system? |
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Definition
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mast cell that start inflamm. process? |
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Definition
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uncapsulated part of the lymph system where cells go to mature? |
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Definition
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Definition
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what do the plasma B cells do? |
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Definition
send antibody to attack the antigen |
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antibody hoooks up with the antigen where at? |
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Definition
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the primary immune response (cd4) happens when? |
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Definition
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Definition
take out introns
take out part of exons |
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Term
with TRNA the amino acid matches with the anitcodon of? |
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Definition
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At the end of meoisis 1 copy of chromosomes witch ends why? |
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Definition
so we have unique gametes |
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what is genetically composed material called? |
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Definition
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both parents have homozygotes alleles.. what is the chance the child will have the allele? |
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Definition
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what do stressed cells want to do? |
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Definition
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what are free radical cells? |
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Definition
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when you have a hypoxic cell injury whta happens? |
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Definition
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what are the adnvantages of apotosisis over necrotic tissue? |
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Definition
natural process
no inflammatory process |
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when there is cell membrane damage what does this do to the cell? |
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Definition
causes the cell to shrink |
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what is the general adaption system? |
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Definition
action of hormones in stressful times |
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cortisol is the stress hormone what does it do? |
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Definition
alters fat, glucose and protein metabolism |
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Definition
vasoconstictor and decreased urine output |
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nor/epiniphrenine does what? |
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Definition
increased BP, HR and decreased urine output |
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Definition
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Definition
increased blood volume and BP and decreased urine output |
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whta happens during the vascukar stage of acute inflamation? |
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Definition
intial vasoconstriction follwed by vasodilation
capillaries more permable and inflamm. mediatiors released |
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Term
what does and increased number of bands indicate? |
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Definition
not enough WBCS manufactured |
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Term
you have a pt with a fever what causes the tempertaure increase? |
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Definition
pyrogens give false set point and go to hypothalamus |
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You are taking care if a ICU patient with a gunshot wound to the chest. He has a fever for longer then 24 hours, but then returns to normal what do you call this? |
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Definition
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If you have a patient with SIRS what can you expect to see? ( when inflam goes systemic) |
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Definition
vasodilation, increased vascular permability, and maldisbrition of fluids |
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what is disturbtive shock? |
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Definition
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what is cold shock described as ? |
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Definition
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you have a pt with a abdomen wound.. what do you want to see? |
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Definition
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what is the difference btw lyphoma and leuekemia? |
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Definition
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difference btw hogdkins and non hogdkins |
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Definition
hodgkins invade with reed sternburg cells |
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mononuclueosis infects a person with EBV virus what does this effect? |
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Definition
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patient with AML is experiencing bruising easily and epistaxis what causes these s/s? |
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Definition
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a patient with multiple mylema is experiencing renal failure why? |
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Definition
bence jones proetin are being excreted in urine..damage |
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Definition
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when clot retracts what causes it to breakdown? |
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Definition
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what is the diff. btw the platelet disorder ITP & TTP? |
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Definition
ITP is the destruction of platelets |
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Term
What is the treatment for a genetic bleeding disorder? |
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Definition
replacement of factor via IV |
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where is the most of the fluid found? |
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Definition
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what would a hypotonic solution cause a cell to do? |
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Definition
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pressure that keeps the fluid inside of capillaries? |
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Definition
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hypothalamus maintains h2o balance what does it look at? |
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Definition
blood volume and serum osmolarity |
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Term
whta causes the lack of thirt? |
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Definition
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Your patient has an increased Na+ level, and is dehydrated what type of solution would you give? |
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Definition
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Term
why does hyperkalemia cause heart dysrrthmias? |
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Definition
it rasies the RMP to threshold allowing to fire more easily |
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Term
what does parathyroid hormone cause? |
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Definition
increased Ca+ = hypercalemia |
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what causes your muscle to spasm? |
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Definition
hypocalcemia- it makes nerves fire more easily |
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Definition
it causes dysrrthmias of the heart ( life threatening dysrrthmias) |
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If you dont have a normal ph it will affect? |
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Definition
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when can compensation occur? |
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Definition
when PH returns to normal
she gave examples... always pick the ph in normal range EX) pH=7.37 |
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intrepret this blood gas?
ph: 7.34
CO2: 60
HCO3: 20
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Definition
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Term
intrepret blood gas?
ph: 7.52
CO2: 54
HCO3: 27 |
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Definition
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Term
a patient is experiencing fear and anxiety what do you expect their blood gas to be? |
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Definition
resp. alkalosis ( increased pH, and HCo3, decreased CO2)
( prolly going to be hyperventilating) |
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Definition
it perevents the alveloar collapse at exhalation |
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what is true about dead space? |
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Definition
physiological dead space is abnormal and anatomic dead space is normal |
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if ventilation is greater than perfusion what can you expect to see? |
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Definition
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A pt with pulmonary edema how would there diffusion be affected? |
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Definition
d/t edema it will be affected with available surface area and membrane thickness |
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oxyhemoglobin dissociation curve has an acidotic L shift what happens to the affinity? |
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Definition
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if the oxyhemoglobin has an R shift with decreased CO2, temperature and a elevated PH what does this do/ |
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Definition
high affinity- Hgb binds easily to O2 |
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Term
what does carbonic anahrydrase do? |
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Definition
allows CO2 to remain the buffer |
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Term
central chemoreceptors are stimulated by? |
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Definition
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Term
A person is infected with TB the macrophage and cell mediated response causes what? |
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Definition
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Term
diff. btw flu and pneumonia ? |
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Definition
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Term
ARDS is characterized as? |
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Definition
hypoxia that does not respond to increased O2 levels |
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Term
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Definition
pulmonary capillary injury |
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Term
2nd pulmonary edema is due to what? |
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Definition
increased pulm. blood flow, hypoxemia, and pulm. vascular obstruction |
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Term
main cause for axelactisis |
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Definition
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Term
what is known as the permanent dilation of bronchi? |
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Definition
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Term
pulm. embloism mainly comes from where? |
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Definition
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Term
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Definition
heart failure from resp. failure |
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Term
what is a characteristic of emphysema? |
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Definition
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Term
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Definition
increased air space and destruction/loss of alveoli tissue |
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Term
what is chronic bronchitis and what can you expect to see? |
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Definition
due to chronic infections and hypersecretions noted |
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Term
what is pleural effusion? |
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Definition
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Term
tension pneomothorax will cause the tacheal shift why? |
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Definition
pressure change
positive pressure in pleural space causes this |
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Term
what causes kidneys to secrete erythopeotein? |
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Definition
tissue hypoxia starts the process |
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Term
diff. btw retic and mature RBCs? |
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Definition
retic have endoplasmic reticulum and other organelles still but can't carry O2.. mature carry O2 |
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Term
what causes buildup of uncongulated bilirubin? |
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Definition
increased production of RBCs |
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Term
what is megablastic anemia? |
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Definition
defiency in vit. B12 and folic acid |
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Term
what is sickle cell caused by? |
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Definition
decreased O2 in hemoglobin- beta linked together and sickle |
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Term
Vessels that takes blood from R venticle to lungs |
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Definition
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Term
when sacromeree have good even contraction in syntinum what helps act. pot? |
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Definition
incalated disc at gap junction |
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Term
what electrolytes is responsible for heart muscle contraction? |
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Definition
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Term
when do coronary arteries perfuse? |
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Definition
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Man comes into ER with blood loss (severe) what three meanings of life does this mess up? |
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Definition
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Term
when looking at EGD what do you look at? |
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Definition
look at speed and direction |
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Term
what are foam cells considered? |
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Definition
machophage that engulf too much LDL |
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Term
what makes plaque more vulnerable easy to rupture ? |
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Definition
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Term
what are s/s occlusion to peripheral extremities/artery? |
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Definition
pain and pale extremities |
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Term
anuerysm cause wall of artery to weaken and stretch this increases the risk for ? |
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Definition
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Term
a person with DVT.. if it breaks off look for? |
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Definition
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Term
the barorecptors in the carotid/aortic arch are stimualted by? |
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Definition
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Term
what happens when barorecptors and and SNS are stimulated? |
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Definition
vasoconstrict and increased heart rate |
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Term
what does aldosterone do? |
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Definition
reasbsorp H20 and Na+ and increase BP and volume |
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Term
ANP is used to lower BP.. how does it do this? |
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Definition
increased Na+/H2O excretion and vasodilation |
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Term
pt have a BP of 150/90 what stage of HTN is this? |
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Definition
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Term
pericardial effusion will lead to what? |
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Definition
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Term
Unstable angina turns into... |
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Definition
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Term
A person with ACS (acute coronary sydrome) whta do you see on their EGD? |
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Definition
elevated ST wave ( Q wave abnormal) |
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Term
what is the very best way to check for an MI? |
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Definition
tropinin (cardiac marker) |
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Term
diff. btw transmural and subendocardial MI? |
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Definition
transmural entire muscle thickness (worse of two) |
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Term
what is a PCI intervention? |
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Definition
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Term
cardiac remodeling leads to what? |
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Definition
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Term
what are s/s of left sided heart failure? |
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Definition
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Term
a stenotic valve can't do what? |
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Definition
can't open... oens poorly |
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Term
cardogenic shock starts with |
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Definition
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Term
what does the intra aorotic balloon pump do? |
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Definition
takes over work of heart.. decreases work of heart |
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Term
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Definition
netwrok of blood vessels. capilarry bed how absorption and secretion take place |
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Term
which stage of urine formation acts as acid/base buffer/ |
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Definition
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