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Patho Exam 2 Vocab
Terms/Concepts to Understand for Exam 2
15
Pathology
Graduate
10/22/2013

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Term
autocrine
Definition
hormone produced by a tissue affects that tissue; hormones are rarely if ever exclusively autocrine
Term
paracrine
Definition
hormone produced by one tissue affects one or more other tissues without travelling through blood stream
Term
endocrine
Definition
hormone produced by one tissue affects one or more other tissues via the blood stream
Term
negative feedback
Definition
phenomenon which occurs when a factor down-regulates its own production
Term
positive feedback
Definition
phenomenon which occurs when a factor up-regulates its own production; often self-limiting
Term
primary endocrine disorder
Definition
disorder within the gland/organ itself, causing abnormal hormone production
Term
secondary endocrine disorder
Definition
disorder within the corresponding lobe of the pituitary which stimulates a gland or organ, causing abnormal hormone production
Term
tertiary endocrine disorder
Definition
disorder within the hypothalamus, causing abnormal stimulation of a gland or organ, causing abnormal hormone production
Term
myxedema
Definition
inflammation and swelling caused by the deposit of mucopolysaccharides in the dermis as a result of HYPOTHYROIDISM
Term
cretinism
Definition
severe stunting of physical and mental growth secondary to congenital HYPOTHYROIDISM
Term
exophthalmos (endocrine)
Definition
Bulging of the eyes from the orbit due to deposits of connective tissue in the orbit; secondary to Graves' disease (autoimmune disorder causing hypothyroidism)
Term
anabolic
Definition
constructive (little orphan Annie always builds you up)
Term
catabolic
Definition
destructive (cats, when clawed)
Term
mineralocorticoids
Definition
sterOID hormones related to water and electrolyte (or MINERAL) balance regulation, primarily Aldosterone; produced in the adrenal CORTex
Term
glucocorticoids
Definition
a sterOID hormone produced in the adrenal CORTex which assists in the metabolism of GLUCOse
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