Term
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Definition
Inhib protein synth (30S)
Nephrotixicity Ototoxicity
Renal Adjust
Commonly used in combos |
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Term
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Definition
Inhib Cell Wall Synth
Narrow Gm (+) Oral Anaerobes
Renal Adjust
DOC for syphilis |
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Term
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Definition
Inhib Cell Wall Synth
Some Gm (-)
Enterococcus
Stable in gastric acid PO |
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Term
| Penicillinase Resistant PCN |
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Definition
Inhib Cell Wall Synth
Gm (+) Only
Renal Adjust except Nafcillin/Oxacillin |
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Term
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Definition
Inhib Cell Wall Synth
Pip Few anaerobes, enterococci
Renal Adjust
> Gm (-) activity, High PBP affinity |
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Term
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Definition
Inhib Cell Wall Synth & Inhib B lacs
Anaerobes
Renal adjust
Inhib. allow PCN to work better
AMP/AMOX - Narrow
TIC/PIP - Broad |
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Term
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Definition
Inhib Cell Wall Synth
Gm (+) Some Gm (-) 10% XRxn w/ PCNs
Renal adjust
No enterococcus |
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Term
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Definition
Inhib Cell Wall Synth
Good Gm (+) & (-)
Renal adjust
Anaerobes Cefoxitin Cefotetan
MTT Side chain on cefotetan |
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Term
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Definition
Inhib Cell Wall Synth
Renal adjust
Enhanced Gm (-)
S. Pneumo & Anaerobic
Pseudomonas Ceftazidime & Cefoperazone
Cefoperazone also has MTT side chain |
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Term
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Definition
Inhib Cell Wall Synth
Ok Gm (+) Great Gm (-)
Renal adjust
S. pneumo & pseudomonas |
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Term
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Definition
Inhib Cell Wall Synth
Pseudomonas & Anaerobes
Renal adjust
Pseudomonas Ex. Ertrapenem
Seizure risk
Less XRxn w/ PCN sensitivity |
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Term
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Definition
Inhib Cell Wall Synth
Gm (+) only
Renal adjust
Nephrotoxicity
Red Man Syndrome
DOC for MRSA MSE |
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Term
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Definition
Inhib DNA Gyrase & Topo 4
Great Gm (-)
Renal adjust
Pseudomonas(CIPRO) & Anaerobes
Tendon issues
Prolong QT |
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Term
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Definition
Inhib protein synth(50S)
Atypicals Staph Strep H Flu
NO Renal Adjust
GI SE |
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Term
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Definition
Inhib exog. prod. of folate bacteria need
Many Gm (-) some (+)
Renal adjust
Hemolytic anemia in some
Leukopenia, thrombocyto, agranulocytosis
Inexpensive Old |
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Term
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Definition
Inhib proteins synth (30S)
Some Gm (-) (+) Atypicals Spirochetes
Renal adjust
Interfere bone teeth formation
Fanconi's from old caps (Tetra) |
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Term
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Definition
Metronid - Anaerobes DOC C diff Renal Adj
Clinda - Anaerobes Gm (+) NO RENAL Adjust |
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Term
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Definition
Inhib protein synth -static
MRSA VRE Entero faecium
NO RENAL Adjust but adj for liver
Thromobophlebitis
CYP3A4 Interaxns |
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Term
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Definition
Inhib protein synth unique site
MRSA VRE Staph Strep
Renal Adjust ?
No X Rxns, 100% Bioavail
5-HT Syndrome poss w/ SSRI sympathomimetics |
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Term
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Definition
Inhib RNA polymerase
Gm (+) (-) Anaerobes
NO RENAL Adjust
CYP Inducer DIs
Discolors sweat tears urine |
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Term
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Definition
Inhib protein synth (50S)
Gm (+) (-) Anaerobes
Causes idiosyncratic aplastic anemia
Not used in US much |
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Term
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Definition
Irrev binds to cell membrane
MRSA VRE Gm (+) only
Tx of comp skin inf endocarditis
Renal adjust
Watch CK & muscle myalgia |
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Term
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Definition
Inhib protein synth (30S)
Gm (+) (-) Anaerobes MRSA VRE(faecalis)
Renal ??
Stable to tetra resistant strains |
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