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Definition
| Any disruption in the integrity of the body's surface barrier-kin or mucous membranes-is a potential site for invasion of microorganisms. |
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Definition
| Pathogens transmitted directly from infected tissue or secretions to exposed, intact mucous membranes. Ex: STI's such as gonorrhea, syphilis, chlamydia, and genital herpes. |
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Definition
| When a mother passes the disease to her child by the placenta or during child birth. |
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Definition
| When an ID is transmitted from mother to child during gestation or birth. |
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Definition
| The entry of pathogens via the oral cavity and GI tract. (one of the more efficient means of disease transmission in humans). |
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Definition
| Pathogens that invade the body through the respiratory tract. Defective pulmonary function or mucociliary clearance caused by cystic fibrosis, emphysema, or smoking increase the risk of inhalation-aquired diseases. |
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Definition
| The source of an infectious disease refers to the location, host, object, or substance from which the infectious agent was acquired. |
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Definition
| Substances that alter or destroy the normal function of the host or host's cells. Bacteria mainly produce toxins (endotoxins and exotoxins) |
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Definition
| a lipopolysaccharide (LSP)found in the cell wall of gram-negative bacteria. |
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Term
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Definition
| proteins released from the bacterial cell during cell growth, they enzymatically inactivate/modify cellular constituents, leading to cell death/dysfunction. |
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Definition
| substances/products generated by infectious agents that enhance their ability to cause disease. 4 categories: toxins, adhesion factors, evasive factors, invasive factors. |
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Definition
| bacterial exotoxins that produce vomiting and diarrhea. |
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Term
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Definition
| the pathogen must attach to and colonize the host, can be site specific (mucous membranes, skin), cell specific (T lymphocytes, respiratory or intestinal epithelium), or nonspecific (moist areas, charged surfaces). |
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