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Patho 1 first exam
Immunologic Diseases
43
Pathology
Undergraduate 2
12/07/2010

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Term
Complement Fixation
Definition
involves several proteins found in plasma or body fluids
Term
Recurrent viral, fungal and protozoan infections are usually due to decreased-
Definition
T- cell function
Term
AIDS-
Definition
is ultimately fatal
Term
A male infant age 8 months presents with frequent severe bacterial infections and a strong family history of male relatives who died of severe infections. A likely diagnosis is-
Definition
Selective Immunoglobulin A Deficiency
Term
Severe Combined Immunodeficiency refers to a group of disorders that result from-
Definition
disturbance in the development and function of both T-cells and B-cells
Term
DiGeorge's Anomaly is -
Definition
congenital condition of immunodeficiency that results from hypoplasia thymus
Term
A congenital disorder that is characterized by inadequate B-cell and T-cell function is-
Definition
Wiskott-Aldrich Syndrome
Term
Autoimmune Diseases-
Definition
occur when auto-antibodies develop and begin to destroy the body's own tissues.
Term
Which statement is NOT true of Auto-immune Hemolytic Anemia?
Definition
it is inherited as an autosomal recessive disorder
Term
Chronic atrophic gastritis resulting in decreased gastric production of HCl and storage of intrinsic factor is found in:
Definition
Pernicious Anemia
Term
Idiopathic Thrombocytopenic Purpura
Definition
is an acquired disorder that results from isolated deficiency of platelets
Term
Systemic Lupus Erythematosus
Definition
can inflame and damage tissue any where in the body
Term
Which statement is not characteristic of RA?
Definition
is inherited as an autosomal dominant
Term
The form of Rheumatoid Arthritis that affects children is called-
Definition
Juvenile RA
Term
Multiple Sclerosis
Definition
is an inflammatory disease of the CNS
Term
Acute attacks of multiple sclerosis may be treated with -
Definition
corticosteroids
Term
Small Vessel Vasculitis
Definition
primarily affects capillaries, arterioles, and venules
Term
Systemic Necrotizing Vasculitis
Definition
can be diagnosed by biopsy demonstrating invasion of leukocytes in blood walls
Term
Chronic Mucocutaneous Candidiasis
Definition
is characterized by persistent and recurrent candidal infections of skin, nails, and mucous membranes
Term
Stem cells which produce all cells of the hematopoietic system are initially produced by -
Definition
fetal liver
Term
Tingling and numbness in extremities is a common symptom in -
Definition
Pernicious Anemia
Term
A patient presents with several joints that are red, hot, swollen and acutely tender. The most likely diagnosis is:
Definition
R A
Term
An immunocompetent immune system responds appropriately to an antigen and homeostasis is maintained.
Definition
TRUE
Term
Pernicious Anemia is caused by-
Definition
the over production of HCl by the gastric mucosa
Term
Cytotoxic T-cells directly destroy virus infected cells and tumor cells by-
Definition
releasing certain toxins
Term
Active Immunity results when a person has had previous exposure to a disease or has received an
Definition
immunization
Term
Immunodeficiency disease can occur in any of the major components of the immune system--B cells, T cells, complement, phagocytes
Definition
TRUE
Term
All immunodeficiency conditions are congenital-
Definition
FALSE
Term
Goodpasture's Syndrome is an autoimmune kidney disease characterized by the presence of antibody against an antigen in the-
Definition
glomerular membrane
Term
The diagnosis of multiple sclerosis is difficult because the symptoms are so variable and sporadic.
Definition
TRUE
Term
The fetal liver produces stem cells which produce all cells of the hematopoietic system
Definition
TRUE
Term
B-cells are coated with immunoglobulins giving them the ability to recognize foreign protein and stimulate an antigen-antibody response.
Definition
TRUE
Term
Increased susceptibility to bacterial infections results from B-cell deficiency.
Definition
TRUE
Term
Infection with HIV can be detected by lab test within 5-10 days.
Definition
FALSE
Term
Acquired Hypogammaglobulin is an acquired T-cell deficiency that results in an absence of antibody production.
Definition
FALSE
Term
In Selective Immunoglobulin A Deficiency the B-cells are not secreting IgA.
Definition
TRUE
Term
Severe Combined Immunodifiency is due to defect in stem cell differentiation into B and T cells
Definition
TRUE
Term
In Autoimmune Hemolytic Anemia the atrophy of the gastric mucosa leads to failure of absorption of Vitamins B 6 and Vitamin C.
Definition
False
Term
ITP is an acquired disorder that results from isolated deficiency of platelets.
Definition
TRUE
Term
Systemic Lupus Erthematosus occurs with equal frequency in men and women.
Definition
FALSE
Term
If R A involves the neck, the spinal cord is at risk for damage.
Definition
TRUE
Term
Multiple Sclerosis is an inflammatory disease that attacks the myelin sheath covering nerves in the brain and spinal cord.
Definition
TRUE
Term
Myasthenia Gravis results from scaring of nerve endings at the neuromuscular junction.
Definition
True
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