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Path - Test 2
Pathology midterm 2
78
Health Care
Graduate
10/23/2011

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Cards

Term
krukenberg spindle
Definition
iris pigment epithelium deposited on the cornea
Term
pseudoexfoliation
Definition
fibrous type of material comes from lens.
flaky white material on anterior lens capsule
difficult to treat
can clog TM
Term
hypopyon
Definition
pus accumulated in AC, can be infectious or non-infectious
Term
anterior IOL CI
Definition
never dilate
Term
posterior embryotoxin
Definition
prominent/anteriorly placed Schwalbe's line
Term
parts of TM (3)
Definition
juxtacanalicular, corneoscleral, inner uveal
Term
Gonio view (anterior to posterior)
Definition
Schwalbe's line
Trabecular meshwork
(Schlemm's canal)
Scleral Spur
Ciliary Body
Term
double hump sign
Definition
angle closure in younger patients
Term
sampaolesi's line
Definition
Pigmented deposition anterior to Schwalbe's Line, pigment dispursion syndrome
Term
blunt trauma can cause
Definition
angle recession
Term
coloboma
Definition
improper closure of fetal fissure "keyhole"
Term
iridodialysis
Definition
root torn away, trauma
Term
LIP
Definition
laser peripheral iridotomy
Term
rubeosis
Definition
neovascularization of the iris
Term
open angle glc - secondary (4)
Definition
steroid induced
angle recession
pseudoexfoliation
pigment dispersion

90% glc in US open angle
Term
closed angle glc - epidemiology
Definition
chinese >>>>>> C = AA
Term
IOP (mean, skew, two SD above mean)
Definition
15.5 +- 2.57
skew to higher pressure
20.6 (21 mmHg)
Term
angle recession
Definition
abnormally wide ciliary body
blunt trauma history
Term
pigment dispersion
Definition
krukenberg spindle

Young white males myopes

less than 40 y.o.
M more than F
Caucasian only
myopes with nice open angles
Term
causes of angle closure glc - iris pushed forward (4)
Definition
pupillary block plateau iris tumors choroidal hemorrhage
Term
causes of angle closure glc - iris pulled forward (3)
Definition
rubeosis iridis inflammation iridocorneal-endothelial syndrome (ICE)
Term
pupillary block glc
Definition
narrow angles, shallow ant chamber depth (less than 1.5 mm), thickening lens, iris insertion, iris configuration
Term
mid-dilated pupil
Definition
possible acute angle closure glc
"Do you see halos at night?"
Term
glaukomflecken
Definition
Clinically: flecks of patch anterior subcapsular opacities associated with severe elevation of IOP - evidence of past acute angle glc. ischemic surface of the lens.
Term
chronic angle closure glc (2)
Definition
1. WITHOUT PAS, angle opens upon indentation gonioscopy
2. WITH PAS, S&T>N>I

look for black pigment in TM, often CONFUSED WITH POAG
Term
syneresis
Definition
natural aging
Term
Photopsia
Definition
flashes of light

PVD, aura w/ or w/o HA, retinal break, retinal detachment, occipital lobe infarction
Term
Shafer's sign
Definition
tobacco dusting - pigment cells within posterior lenticular space (berger's space), indicate retinal detachment
Term
asteroid hyalosis
Definition
globules of calcium soaps aggregate on vitreous fibrils
Term
weiss ring
Definition
complete PVD
remnaat of cortex attached to ONH
Term
white without pressure
Definition
prominent vitreous base
Term
reticular pigment degeneration
Definition
normal peripheral change in elderly
Term
congential hypertophy of the RPE (CHRPE)
Definition
bear tracks
Term
RRD risk
Definition
aphake 2%
low myopia 4x
high miyopia 10x
M/F, tramua, 20-29yo
lattice degeneration
early syneresis
cataract surgery 10%
prophylatic prior to CE
RD of fellow eye 15% (but prophylaxsis reduces risk to 3%)
retinoschisis, degenerative myopia, lattice degeneration, trauma, PVD
Term
% population with retinal break
Definition
5-15% atrophic retinal holes, develop WITHOUT vitreoretinal traction
Term
retinal dialysis
Definition
retinal tear at the ora serrata, secondary to trauma
Term
indocyanine green angiography
Definition
occulut choridial neo eval
Term
vascular vs neuro midline
Definition
vacular respects horizontal
neurological respects vertical
Term
angioid streaks
Definition
breaks in bruchs membrane and tend to migrate from the ONH
Term
posterior staphyloma
Definition
degenerative myopia
Term
lacquer cracks
Definition
degenerative myopia
run parallel
also break in bruchs membrane
neo
Term
commotio retinae
Definition
brusing of the retina
Term
wedge or slit defect
Definition
NFL dropout
Term
retinitis pigmentosa
Definition
does not respect any meridians, photoreceptor cell death
Term
ALR
Definition
arteriole light reflex, "silver-wiring" = a sclerosed vessel.
venuous beading.
Term
superficial hemorrhage
Definition
artery based. flame shape.
Term
deeper retinal hemorrhage
Definition
pre-venular. congestive dz. dot-blot. results from compression. follow vertical cleavage lines. NO tissue necrosis
Term
pre-retinal hemorrhage
Definition
scotoma. between NFL and ILL
Term
roth spot
Definition
hemorrhage surrounding a white center in inflammatory dz. white = CWS/leukemia cells/fibrin surrounded by heme.
Term
red vs gray-green hemorrhage
Definition
red = subretinal
gray/green = sub-RPE (deeper)
Term
CNV
Definition
choroidal neo. any pathologic process that invovles the RPE and damages bruch's membrane
Term
macroaneurysm
Definition
need cardio workup. high mortality rate. 50% htn, 25% mortality

microaneurysm - diabetic retinopathy (DR)
Term
CWS
Definition
microinfacrt. swelling of local nerve fiber AXONS and LOSS OF TRANSPARANCY. bifurcation.
Term
IRMA
Definition
intraretinal microvascular abnormalities. DO NOT LEAK. near CWS
Term
types of emboli
Definition
cholesterol
calcium
platelets
fibirin
talc or constrach
Term
cherry spot
Definition
central retinal artery occlusion
Term
macular star exudates
Definition
in NFL, htn crisis.
Term
strawberry sunday
Definition
central vein occlusion
Term
pre-proliferative
Definition
capillary wall collapse/dropout
Term
proliferative
Definition
neo
Term
NVD
Definition
within 1DD of ONH, 25% pts with PDR - proliferative diabetic retinopathy
Term
capillary leakage (3)
capillary non-perfusion/dropout (3)
Definition
-microaneurysms, hemorrhages, exudates
-CWS, venous beading, IRMA
Term
PRP
Definition
pan retinal photocoagulation
Term
diabetics ____X more likely to go blind than non-diabetics
Definition
25X
Term
Stargardt's dz, best's dz
Definition
hereditary macular disease
Term
types of macular drusen (3)
Definition
discrete - 80% population
"soft" - over 55yo - AMD, waxy larger
confluent - AMD
Term
pigment mottling
Definition
RPE atrophy - focal changes in pigmentation
Term
CSME
Definition
clinically significant macular edema
Term
disciform scar
Definition
fibrotic glial tissue overtakes neurosensory tissue. NO CENTRAL VISION. can happen overnight.
Term
ERM
Definition
epiretinal membrane - cellophane maculopathy. Fibrotic tissue. pseudo-hole
Term
Pseudo-hole (5)
Definition
ERM contraction
RRD
inflammation
trauma
venous occlusive dz
Term
lamellar hole
Definition
precursor to full-thickness macular hole or be a self-healed hole
Term
Watzke-Allen
Definition
full thickness hole? 3mm beam, 78D, look for split/separation in beam
Term
PED
Definition
pigment epithelial detachment - detachment from BM
Term
CME
Definition
cystoid macular edema - complication of cat surg
Term
bull's eye maculopathy
Definition
plaquinel - for autoimmune dz's
Term
salt and pepper maculopathy
Definition
throidazine/chlorpromazine
Term
crystalline maculopathy
Definition
tamoxifen
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