Term
| These tumors account for 80% of all aldult primary brain tumors. They are grey and poorly defined. Attributable to p53 mutation and over exression of DPGF-A. |
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Definition
|
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Term
| Grey and poorly defined. Indistinct transition between normal and cancerous tissue. |
|
Definition
| Infiltrating Astrocytoma Grade II (Diffuse Astrocytoma) |
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Term
| Grey, no necrosis, and poorly defined.Densely cellular with mitotic figures and pleomorphic nuclei. |
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Definition
| Infiltrating Astrocytoma Grade III (Anaplastic Astrocytoma) |
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|
Term
| Grey, necrosis, cystic degeneration, hemorhage. Vasculature or endothelial proliferation. Appear Pseudopalisading. Disruption of tumor supressor genes. |
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Definition
| Infiltrating Astrocytoma Grade IV (Glioblastoma) |
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Term
| Cytic, well circumscribed. Hiary-like fibrillary network. Children and young adults in the cerebellum. No p53 mutation. |
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Definition
| Pilocytic Astrocytoma (Grade I) |
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Term
| Often in children and young adults. Temporal Lobe with history of seizures. Reticulin and inflamation. Appears simila to glioblastoma but without necrosis or mitotic activity. |
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Definition
| Pleomorphic Xanthoastrocytoma |
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Term
| Account for 20% of primary brain tumors in age<20. Course varies with location. |
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Definition
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Term
| Occur in the 40-50 age groups. Several years of neurocomplaints(seizures). Prefer white matter of cerebral hemispheres. |
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Definition
|
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Term
| Well circumscribed, gray, calcification, cyts. Halo around nuclues. No mitotic activity. Loss of heterozygosity of 1p and 19q. |
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Definition
|
|
Term
| Well circumscribed. Increased cell density, Increased capilaries with thin walls |
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Definition
| Anaplastic Oligodendrogliomas |
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|
Term
| loss of 1p and 19 q only, no other molecular changes. |
|
Definition
| Easily treatable olgiodendrogliomas |
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|
Term
| Tumor associated with neurofibromatosis type 2. Age<20 = 4th ventricle. Adults=spinal cord. |
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Definition
|
|
Term
| Associated with perivascular peudoROSEttes |
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Definition
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Term
|
Definition
|
|
Term
| Non-neoplastic. Young adults. Obstructive hydropcephalus. Positional head aches. |
|
Definition
| Colloid Cyst of 3rd Ventricle |
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|
Term
| Found at autopsy, incidental. Very slow growing nodules in ventricles. |
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Definition
|
|
Term
| In children = lateral ventricles adults=4th ventricle. Hydrocephalus. |
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Definition
| Choroid Plexus papillomas |
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|
Term
| Presents with seizures. Relatively slow growing, but become morbid as glial cells also become anaplastic. Binucleate ganglion cells |
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Definition
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|
Term
| Presnets as childhood seizure disorder. Multiple intracorticle lesions. Well differentiated. Floating neurons. |
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Definition
| Dysembryoplastic Neuroepithelial Tumor |
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|
Term
| Primative, undifferentiated neuroectdermal cells. |
|
Definition
| Poorly differentiated neoplasms (all) |
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|
Term
| Always in cerebellum. Occurs in kids. Well circumscribed.abundant mitoses. Drop metatstais. |
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Definition
|
|
Term
| Young children, rapidly fatal. Rhabdoid cells. Spread along brain surface. Alteration in Chromosome 22. |
|
Definition
| Atypical Teratoid / Rhabdoid Tumor |
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|
Term
| Immunospuressed individuals. Associate with Epstein-Barr Infection. Hooping of cells. |
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Definition
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|
Term
| Tumor of the young. Increased in Japanese. Can be a metastic growth from gonads |
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Definition
|
|
Term
| Whorled pattern. Psamomma bodies. In the dura. Deletion of 22q12. |
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Definition
|
|
Term
| Miningioma with increased mitoses. |
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Definition
|
|
Term
| Meningioma with extreme mitosis. Sarcaoma like appearance. |
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Definition
|
|
Term
| Carcinoid tumors from many places go the brain (minus prostate). Sharply demarcated. |
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Definition
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|
Term
|
Definition
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|
Term
| Often affect CN 8. Merlin is not expressed. Verocay Bodies. Have S-100 antigen. |
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Definition
|
|
Term
| Lesion in SQ fat or skin, costmetic concern. |
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Definition
|
|
Term
| Lesion in large nerve trunks, multiple. Can not separate from nerve. Shredded carrot appearance. |
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Definition
|
|
Term
| Assocaited with NF1. poorly defined. Triton tumors. |
|
Definition
| Malignant peripheral nerve sheath tumor |
|
|
Term
| Schwanomma symptoms that reacts with S-100, not keratin. |
|
Definition
| Epitheloid Malignant schwannoma |
|
|
Term
| Li-Fraumeni, Turcot, Gorlin |
|
Definition
| Familial cause of medulloblastoma |
|
|
Term
| AD, Optic Nerve gliomas, Café au lait spots, defect in NF1 |
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Definition
|
|
Term
| AD, bilateral CN 8 schawanommas. Hamartomas. Defect in merlin. |
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Definition
|
|
Term
| AD Hamartomas in the CNS. Many other lesion in body possible. |
|
Definition
| Tuberous Sclerosis Complex |
|
|
Term
| AD, cyts in kidney, liver, pancreas. Pheochromocytoma. Ubitquitin ligase error. |
|
Definition
| Von hippel-Lindau Disease |
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