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Assessment of clinical trial by experts for scientific merit, participant safety, and ethical considerations. |
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Extensive heterogenous collection of resources which provide information about drugs |
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Direct research
Includes controlled clinical trials, case control studies, crossover trials, case reports, case series, cohort studies, meta-analysis, pharmacoeconomics, Canadian Medical association Journal (CMAJ) |
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Database referring to primary resources. eg. Medline, pubmed, international pharmaceutical abstract, EMBASE, and cochrane database, Clin-Alert, Medline, Weekly-Clinical Practice, International Pharmacy Practice |
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Can have bias
Textbooks, review articles, US and compendium, CPS, manufacturer leaflets, TC, Martindale, Remington |
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Controlled study in a SINGLE SUBJECT where periods of exposure are compared to placebo to determine the effects of treatment on various variables |
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Big limitation of secondary resources |
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Relying on individual secondary resources to find specific studies etc. is a bad idea because some secondary resources only provide lists of specific journals |
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What source provides most current information? |
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Resources for Drugs manufactured in the US |
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The American Drug Index Drug Facts and Comparisons Drug Topics Red book PDR - Physicians Desk Reference American Hospital Formulary Society (AHFS) |
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Resource for International Drugs |
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MARTINDALE
Index Nominum, USP Dictionary, USAN |
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Martindale, Drug Facts and Comparison (US), Unlisted Drugs, The NDA - New Drug Application pipeline |
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Identifying unknown drugs |
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USP-DI volume I, PDR, Drug Facts and Comparisons |
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Meyler's side effects of Drugs USP DI. Vol 1 CPS Drug Facts and Comparison Clin-Alert Martindate AHFS drug info |
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Drug Interactions:
Drug interactions Facts, CPS, Clin-Alert, Hansten & Horn Drug Interactions, Drug-Drug Interactions, Handbook of Drug Interactions, 'Importance and Management', EDI (Evaluation of Drug Interactions) |
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Availability of Dosage forms |
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Red Book American Drug Index |
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Drug Prescribing in Renal Failure |
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Drug-Lab Test Interactions |
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AHFS Effects of Drugs on Clinical Laboratory Tests Drug-Laboratory Test Interferences |
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Drug Interaction Facts USP-DI Volume I Reference Guide to Drug and Nutrient Interactions Food Medications Interactions Handbook HIV Medication-Food Interactions |
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Drug-Herb Interactions:
Database of Natural product Herbs: Everyday Reference for Health Professionals Herb Contraindications and Drug Interactions Herb Drug Interactions Drug Interaction Facts Interactions Between Drugs and Natural Medicines Must Know About Vitamins, Minerals, Foods and Herbs |
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Compounding and Extemporaneous prep |
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Compounding and Extemporaneous prep
Extemporaneous Formulations Remington Merck Index USP-NF (United States Pharmacopea National Formulary) Pharmaceutical Dosage Forms and Drug Delivery Systems Pharmaceutical Practice The Art, Science, and Technology of Pharmaceutical Compounding The Pharmaceutical Codex |
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Definition
Martindale USP-NF Merck Index British Pharmacopeia Contemporary Compounding Compendium Extemporaneous Oral Liquid Dosage Preparations (CSHP) The Ghen and Rains Physician's Guide to Pharmaceutical Compounding Extemporaneous Formulations Pediatric Drug Formulations Pocked Book of Extemporaneous Formulations Allen's Compounded Formulations: US Pharmacists Collection The Art, Science, and Technology of Pharmaceutical Compounding Trissel's Stability of Compounded Formulations (for parenteral stabilities) Minutes from Manufacturer |
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Characteristics Of Specific Chemicals/Drugs |
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Definition
Merck Index Martindale Remington Pharmaceutical Codex Handbook of pharmaceutical excipients US Pharmacopeia- NF Trissels Stability of Compounded Formulations Guidelines for Preparation of Sterile Products in Pharmacies CSHP |
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Compatibility and Stability of Parenteral Drug |
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Handbook of injectable drug (Trissel) King guide to parenteral admixtures Trissels table of physical compadibility IV index system |
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Identification of Foreign drugs |
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Martindale Index nominum United states adopted names USP dictionary of drug names |
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USP DI vol 1 AHFS drug info Handbook of clinical drug data |
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USP DI vol 2 communication skills in pharm practise communication skills for pharmacists |
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Drugs in pregnancy and lactation Mother risk program AHFS drug info Clinical therapy in breast feeding patients N/V in pregnancy USP DI 1 CPS |
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Martindale Neofax Red Book Harriet Lane handbook |
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Current therapy in Equine medicine Environmental Contaminants |
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Doses in Drug Administration |
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PDR Drug Facts and Comparison Martindale |
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IV and IM compatibilities |
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PDR Drugs in Pregnancy and Lactation |
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Complete reference of foreign drugs and off label drugs.
Monographs and ancillary New Drugs Obsolete drugs and Miscellaneous Substances OTC Directory of world wide Pharmaceutical manufacturers |
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Drug info
- Monographs, indications, interactions, PK, Adverse effects, counseling guidelines, Label and Off Label Use to facilitate third party reimbursement |
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Advice for patients in lay mans terms
- similar to volume 1 in counseling but patient oriented. |
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Approved drug products and legal requirements
- Packaging, labeling, and storage requirements |
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Federal guidelines and legislation |
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Source of generic drug names - Includes brand names, chemical names, and from different countries (Japanese, British, American) |
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Chemical properties and compounding |
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Anatomy, physiology, Patho |
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Appraisals of new drugs and comparative reviews of older drugs |
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Pharmaceutics, therapeutics, history of pharmacy, ethics, industrial & pharmacy practice. |
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Online source of Indexes and abstracts |
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SOP (Standard Operating Procedures) |
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Standard operating procedures used in preparation and formulation of pharmaceuticals. |
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