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Function of muscle tissue |
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Body movements Stabilize body position Regulate organ volume Move substances within Generate heat |
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ability ot be extended or stretched without damage |
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microscopic anatomy location How they are controlled by nervous and endocrine |
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plasma membrane of muscle cell contain transverse t-tubules |
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Small, cylindrical invaginations of teh sarcolemma of striated muscle fibers that conduct muscle action potentials toward teh center of the muscle fiber. |
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Muscle cell contracts, thin filaments slide past the thick filaments and sarcomere shortens |
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Steps of cross bridge cycling |
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Exposure of binding sites on actin Binding of myosin to actin Power stroke of the cross bridge Disconnecting the cross bridge Re-energizing the cross bridge Removal of calcium ions |
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ADP and Pi are released from actin Myosin head tilts backward Power stroke occurs as thin filament is pulled inward toward center of sarcomere |
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Sarcolemma to sarcoplasmic reticulum active transport pump |
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Role of ATP in muscle contraction |
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Transfers energy to myosin cross bridge, which energizes power stroke Disconnects myosin cross bridge from binding site on actin Fuels pump that actively transports calcium ions back to SR |
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Creatine phosphate: 1st store, Glycolysis/anaerobic pathway: 2 ATP, and 2 pyruvic acid into 2 lactic acid into blood bc not enough oxygen Aerobic pathway: pyruvic acid enters mitochondria, generates ATP, 1 glucose=36 ATP |
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Refers to the added oxygen, over and above the resting oxygen consumption, that is taken into the body after exerces. Used to restore metabolic conditions of resting level by 1. converting lactic acid into glycogen 2. Resynthesize creatine phosphate and ATP 3. Replace oxygen removed from myoglobin |
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Synapse between a somatic motor neuron and a skeletal muscle fiber. Synaptic end bulbs on one side and motor end plate on other Axon and Sarcolemma |
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The end of the motor neuron divides into a cluster Contain synaptic vesicles which contain acetylcholine |
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Breakdown of acetycholine |
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broken down by enzyme, acetylcholinesterase which is attached to collagen fibers |
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Nerve impulse elicits muscle action potential steps |
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1. Release of acytelcholine 2. Activation of ACh receptors 3. Production of muscle action potential 4. Termination fo ACh activity |
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Motor neuron together with the muscle fibers (cells) it stimulates |
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Increases in calcium ions starts muscle contraction Calcium leaks out of sarcoplasmic reticulum Myosin heads bind to actin ATP synthesis has ceased, cross bridges cannot detach Muscles are rigid |
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nervous system responsibilities |
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somatic: voluntary autonomic: involuntary sympathetic: fight/flight parasympathetic: rest/digest enteric: involuntary, GI tract |
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Nerve impulses arise here, junction of axon hillock and initial segment. |
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Graded potential Action potential |
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short distance communication long distance |
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Resting membrane potential polarization |
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negative ions inside positive ions outside potassium higher inside? |
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greater frequency of action potentials |
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period of time after an action potential begins during which an excitable cell cannot generate another action potential in response a normal threshold stimulus. Therefore stimulus must be high |
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Absolute refractory period |
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even a strong stimulus canoot initiate a second action potential |
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Na+ (sodium) moves into neuron through channels |
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If a stimulus is strong enough to generate an action potential, the impulse generated is of a constant size. |
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