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Part 2: Chapter 9
The Somatic Sensory System: Touch & Proprioception
47
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Undergraduate 2
10/01/2014

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Term
pseudounipolar
Definition
neurons in the dorsal root ganglia; peripheral & central components of afferent fibers are continuous, attached to the cell body in the ganglia by a single process
Term
sensory transduction
Definition
the process of converting the energy of a stimulus into an electrical signal
Term
receptor potential (AKA generator potential)
Definition
a depolarizing current generated by the alteration of the permeability of cation channels in afferent nerve endings due to a stimulus
Term
mechanoreceptors
Definition
specialized receptor cells that often encapsulate afferent fibers; help tune the afferent fiber to particular features of somatic sensation
Term
free nerve endings
Definition
afferent fibers that lack specialized receptor cells; especially important in the sensation of pain
Term
Ia afferents
Definition
the largest-diameter sensory afferents; supply the sensory receptors in the muscles; make primary endings; largest myelinated sensory axons
Term
AB afferents
Definition
afferents that convey most of the information subserving tough; slightly smaller diameter fibers than Ia
Term
Ad and C afferents
Definition
convey information about pain & temperature; small diameter fibers
Term
receptive field
Definition
the area of the skin surface over which stimulation results in a significant change in the rate of action potentials; used to distinguish sensory afferents
Term
two-point discrimination
Definition
the minimum interstimulus distance required to perceive two simultaneously applied stimuli as distinct; varies dramatically across the skin surface
Term
rapidly adapting afferents
Definition
those that become dormant in the face of continued stimulus; particularly effective in conveying information about changes in ongoing stimulation such as those produced by stimulus movement
Term
slowly adapting afferents
Definition
better suited to provide information about the spatial attributes of the stimulus such as size & shape; opposite of rapidly adapting afferents
Term
haptics
Definition
active touching; involves the interpretation of complex spatiotemporal patterns of stimuli that are likely to activate many classes of machanoreceptors
Term
stereogenesis
Definition
a capacity by which manipulating an object with the hand can often provide enough information to identify the object
Term
Merkel cell afferents
Definition
slowly adapting fibers that account for about 25% of the mechanosensory afferents in the hand; in the fingertips; only afferents to sample information from receptor cells located in the epidermis
Term
Meissner afferents
Definition
rapidly adapting fibers that innervate the skin even more densely than Merkel afferents; account for about 40% of the mechanosensory innervation of the human hand; formed by a connective tissue capsule that comprises several lamellae of Schwann cells
Term
Pacinian afferents
Definition
rapidly adapting fibers that make up 10-15% of the mechanosensory innervation in the hand; located deep in the dermis or in the subcutaneous tissue; resembles a small onion (concentric layers of membranes surrounding a single afferent fiber)
Term
Ruffini afferents
Definition
slowly adapting fibers; least understood of the cutaneous mechanoreceptors; elongated, spindle-shaped, capsular specializations
Term
muscle spindles
Definition
found in all but a few skeletal muscles; give the most detailed knowledge about proprioception
Term
intrafusal muscle fibers
Definition
four to eight of these make up muscle spindles & are surrounded by a capsule of connective tissue
Term
extrafusal fibers
Definition
true force-producing fibers; in skeletal muscle; run in a parallel arrangement with intrafusul muscle fibers & contain some as well
Term
group II afferents
Definition
secondary endings; produce sustained responses to constant muscle lengths; opposite of group Ia afferents
Term
Golgi tendon organs
Definition
low-threshold mechanoreceptors in tendons that inform the central nervous system about changes in muscle tension
Term
group Ib afferents
Definition
branches of these make up Golgi tendon organs and are distributed among the collagen fibers that form the tendons
Term
joint receptors
Definition
resemble many of the receptors found in the skin; mechanoreceptors in and around the joints
Term
dorsal columns (AKA posterior funiculi)
Definition
where the axons of cutaneous mechanosensory afferents ascend through the spinal cord; leads the axons to the lower medulla where they synapse on neurons in the dorsal column nuclei
Term
fasciculus gracilis
Definition
a circumscribed bundle in which fibers conveying information from lower limbs travel
Term
fasciculus cuneatus
Definition
a lateral bundle in which fibers that convey information from the upper limbs, trunk, & neck lie
Term
The _____ in the dorsal column nuclei send their axons to the somatic sensory portion of the thalamus
Definition
second-order neurons
Term
internal arcuate fibers
Definition
the axons exiting from the dorsal column nuclei
Term
medial lemniscus
Definition
a dorsoventrally elongated tract formed by the internal arcuate fibers that cross the midline
Term
the crossing of the internal arcuate fibers is called the _____ of the medial lemniscus
Definition
decussation
Term
ventral posterior lateral nucleus/VPL
Definition
where the axons of the medial lemniscus synapse with thalamic neurons
Term
_____ in the VPL send their axons via the internal capsule to terminate in the postcentral gyrus of the cerebral cortex, a region known as the primary somatosensory cortex (AKA SI)
Definition
third-order neurons
Term
secondary somatosensory cortex/SII
Definition
a smaller region than the primary somatosensory cortex that lies in the upper bank of the lateral sulcus; another place where neurons in the VPL send their axons
Term
trigeminal ganglion/cranial nerve V ganglion
Definition
where first-order neurons are located that centrally convey cutaneous mechanoreceptor information from the face
Term
what are the three main subdivisions of the trigeminal nerve? (formed by the peripheral processes of the trigeminal ganglion)
Definition
1. ophthalmic
2. maxillary
3. mandibular
Term
trigeminal brainstem complex
Definition
where the trigeminal ganglion cells terminate on neurons after entering the brainstem at the level of the pons
Term
2 major components of the trigeminal complex
Definition
1. principal nucleus
2. spinal nucleus
Term
ventral posterior medial nucleus/VPM nucleus
Definition
where axons of the second-order neurons of the trigeminal brainstem nuclei ascend to after crossing the midline
Term
trigeminothalamic tract (AKA trigeminal lemniscus)
Definition
how the second-order neurons of the trigeminal brainstem complex send their axons to the VPM nucleus
Term
Clarke's nucleus
Definition
located in the medial aspect of the dorsal horn; where first-order proprioceptive afferents that enter the spinal cord between the mid-lumbar & thoracic levels synapse
Term
mesencephalic trigeminal nucleus
Definition
a well-defined cluster of neurons lying at the lateral extent of the central gray region of the midbrain; where the cell bodies of the first-order proprioceptive neurons for the face are found; in the central nervous system
Term
ventral posterior complex
Definition
part of the thalamus; where each of the several ascending somatic sensory pathways originating in the spinal cord & brainstem converge
Term
primary somatic sensory cortex (AKA SI)
Definition
located in the postcentral gyrus of the parietal lobe; comprises 4 distinct regions/fields
Term
4 distinct regions/fields of the primary somatic sensory cortex
Definition
1. Brodmann's area 3a
2. Brodmann's area 3b
3. Brodmann's area 1
4. Brodmann's area 2
Term
secondary somatosensory cortex/SII
Definition
lies in the upper bank of the lateral sulcus; one of the higher order cortical centers to which somatic sensory information is distributed from the primary somatic sensory cortex
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