Term
| The Glomerular Filtration Rate (GFR) |
|
Definition
| Is the amount of filtrate kidneys produce each minute |
|
|
Term
Reduced blood flow or LOW glomerular blood pressure triggers:
what to dilate/constrict(3) |
|
Definition
1.Dilation of afferent arteriole
2.Dilation of glomerular capillaries 3.Constriction of efferent arterioles*
*nothing can leave |
|
|
Term
| Rise /HIGH in renal blood pressure triggers (4) |
|
Definition
1.↑P on walls of afferent arterioles 2.Constricts afferent arterioles
3. smooth muscle cells to contract 4.Decreases glomerular blood flow |
|
|
Term
Hormonal Regulation of the GFR is done by what hormones (6)
seperate these hormone into 2 categories |
|
Definition
•Renin–angiotensin system:
includes:
1.renin
2.angiotensin 2
3.aldosterone
4.anti-diuretic hormone (ADH)
•Natriuretic peptides:
5. ANP
6. BNP |
|
|
Term
| if Blood Volume is increased what are 2 effects (in referece to GFR &what is lossed)? |
|
Definition
| 1. Glomerular filtration will INCREASE & Hormones will also kick in ( further increase GFR) 2.Accelerating fluid loss in urine |
|
|
Term
if body BP is increased then will happpen to:
what system is working
afferent arterioles
GFR? |
|
Definition
Sympathetic Activated
afferent arterioles will constrict=
DECREASE in GFR
(less filtrate formed)
aka you will stop the process of making urine |
|
|
Term
|
Definition
| causes immediate localized homeostatic adjustments |
|
|
Term
|
Definition
| respond quickly to changes at specific sites |
|
|
Term
|
Definition
|
|
Term
| If BP is low the LONG term response is done by? |
|
Definition
| endocrine response by kidneys |
|
|
Term
If BP is low kidneys release(5)
What are the effects in respect to : BP GFR efferent arterioles thirst |
|
Definition
| 1.EPO= increased BV 2.renin 3.angiostensin 2 4.ADH 5.aldosterone effects: BP will INCREASE GFR will INCREASE efferent arterioles will constrict(aka less will leave)= more filtrate formed you will be thristy |
|
|
Term
| If BP is low the neural response is done by? what are the effects with respect to afferent arterioles GFR |
|
Definition
| sympathetic nervous system 1.Constricts afferent arterioles(less coming IN) 2.Decreases GFR (Slows filtrate production) |
|
|
Term
| If BP is low sympatheic nervous system release |
|
Definition
epinephrine
norepinephrine |
|
|
Term
| Norepinephrine and epinephrine cause |
|
Definition
increased caridac output
vasoconstiction
= increased BP & BV |
|
|
Term
| If the BP and BV is high what will be released? |
|
Definition
| natriuretic peptides by heart (ANP) and (BNP) |
|
|
Term
| If ANP & BNP are released what will occur (5) |
|
Definition
1.increased loss of Na+ in urine
2.increased loss of water in urine
(more fluid loss in urine)
3.increase GFR
4.reduced thrist
5. BP & BV (low) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| excessive diastolic stretching, high BP |
|
|
Term
| excessive diastolic stretching and high BP stimulate |
|
Definition
|
|
Term
|
Definition
1.↓ blood volume
2.circulating angiotensin II |
|
|
Term
|
Definition
1.↑ reabsorption of water by distal convoluted tubule=
2.increased BP & BV |
|
|
Term
| angiostensin 2 responds to |
|
Definition
|
|
Term
| angiotensin 2 leads to the production of |
|
Definition
|
|
Term
|
Definition
| juxtaglomerular complex in the kidneys |
|
|
Term
| renin is released when (1) |
|
Definition
|
|
Term
renin also stimulates the production of what hormone?
How is angiotensin II made? |
|
Definition
angiotensiogen to angiostensin I
angiostensin I
to
angiotensin II
by ACE |
|
|
Term
| renin causes vaso constiction or dilation |
|
Definition
| vasoconstriction to increase BP |
|
|
Term
| If blood pressure is high, what will be inh? |
|
Definition
no: ADH
aldosterone epinephrine/norepinephrine
angiotenison II renin |
|
|
Term
| If there is alot of Na+ in blood, your BP is? |
|
Definition
high,
Na+ is going to be lossed in urine |
|
|
Term
| If EPO is needed, your BP and BV |
|
Definition
|
|
Term
| If renin is needed, BP is |
|
Definition
|
|
Term
| Aldosterone needed, BP is |
|
Definition
|
|
Term
| If your are thristy, your BP is |
|
Definition
|
|
Term
| increased ADH, means___ BP |
|
Definition
|
|
Term
| name all hormones that increase BP |
|
Definition
epinephrine/norepinephrine
ADH
AngiotensinII
EPO
renin |
|
|
Term
| name compounds that lower BP |
|
Definition
ANP & BNP
=natriuretic peptides |
|
|
Term
name compounds that increase GFR?
what is constricted |
|
Definition
renin
angiotensin 2
ADH
aldosterone
efferent arterioles (things cant leave) |
|
|
Term
name compounds that decrease GFR?
what is constricted |
|
Definition
epinephrine & norepinephrine
afferent arterioles(things cant come in) |
|
|
