Term
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Definition
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Term
what does the dopamine difeciency lead to? |
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Definition
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Term
what are some of the characteristics of parkinsons? |
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Definition
Tremors of head and neck Rigidity (increased muscle tone) Bradykinesia (slow movement) Postural changes Head and chest thrown forward Shuffling walk Lack of facial expression Pill-rolling motion of hands |
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Term
What are the drugs used for parkinsons? |
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Definition
anticholernergics, dopaminergics, dopamine agonists, MAO-B inhibitors, and COMT inhibitors |
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Term
what are side affects of anticholinergics? |
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Definition
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Term
what do the anticholinergics do? |
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Definition
they block cholinergic receoptors |
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Term
what do dopaminergics do? |
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Definition
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Term
what are some of the anticholinergics that are used? |
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Definition
benztropine (cogentin) and trihexyphenidyl HCL (artane) |
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Term
what is a dopaminergics drugs? |
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Definition
carbidopa-levodopa (sinemet) |
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Term
what do dopaminergics do? |
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Definition
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Term
what are the side effects of dopaminergic drugs? |
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Definition
Fatigue, insomnia, dry mouth, blurred vision Orthostatic hypotension, palpitations, dysrhythmias Urinary retention, nausea, vomiting Dyskinesia, psychosis, severe depression |
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Term
what drugs decrease levodopa effects? |
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Definition
Fatigue, insomnia, dry mouth, blurred vision Orthostatic hypotension, palpitations, dysrhythmias Urinary retention, nausea, vomiting Dyskinesia, psychosis, severe depression |
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Term
what is a dopamine agonists? |
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Definition
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Term
what does amantadine (symmetrel) do? |
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Definition
it stimulates dopamine receptors |
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Term
What is the pathospysiology of alzheimer's disease? |
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Definition
Progressive, degenerative disease Neuritic plaques form Neurofibrillary tangles are in neurons Cholinergic neurotransmitter abnormality |
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Term
what are some of the characteristics of Alzheirmers? |
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Definition
Loss of memory, logical thinking, judgment Time disorientation Personality changes Hyperactivity Tendency to wander Inability to express oneself |
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Term
what are some of the acetylcholinesterase inhibitors? |
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Definition
donepril (aricept) and Rivastigmine (exelon) |
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Term
what do acetylcholinesterase inhibitors do? |
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Definition
they allow more acetylcholine in neuron receptors |
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Term
what are some of the side effects of acetylcholinesterase inhibitors? |
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Definition
Headache, dizziness Depression GI distress Dehydration, dry mouth Blurred vision Insomnia Hypertension, hypotension, dysrhythmias Hepatotoxicity |
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