Term
|
Definition
Levodopa
PD Drug
not used for mild
N&V, orthostatic hypotension, choreiform movements
don't give in glaucoma |
|
|
Term
|
Definition
Carbidopa
PD Drug
inhibits peripheral decarboxylase
decreases s/e: anorexia, N&V, cardiac |
|
|
Term
|
Definition
Domperidone
PD Drug Association
selective for peripheral dopamine receptors,
used as anti-emetic
low yield |
|
|
Term
|
Definition
Propranolol
PD Drug Association
used to treat cardiac arrythmias due to beta adrenergic and peripheral dopamine receptor stimulation with levodopa |
|
|
Term
|
Definition
Clozapine (an antipsychotic...)
PD Drug Association
used to treat behavioral changes due to levodopa |
|
|
Term
|
Definition
Trazodone
PD Drug Association
only tricyclic antidepressant used to treat depression in PD
remember: "trazodone raises the bone" |
|
|
Term
|
Definition
Reserpine
Huntington's Disease
catecholamine depleting agent |
|
|
Term
|
Definition
Fluoxetine
Antidepressant used in Huntington's for depression |
|
|
Term
|
Definition
Meperidine
PD Association
opiate:don't use with selegiline |
|
|
Term
|
Definition
Rasagiline
PD Drug
MAO-B inhibitor, neuroprotective |
|
|
Term
|
Definition
Safinamide
PD Drug
MAO-B inhibitor, dopamine reuptake inhibitor, inhibition glutamate |
|
|
Term
|
Definition
trihexiphenidyl
PD Drug
antimuscarinic/antihistaminergic good in early stages,
amnesia/hallucinations in elderly |
|
|
Term
|
Definition
Benztropine
PD Drug
antimuscarinic/antihistaminergic good in early stages, amnesia/hallucinations in elderly |
|
|
Term
|
Definition
Diphenhydramine
PD Drug
benedryl, weak anti-cholinergic, good for elderly |
|
|
Term
|
Definition
Amantadine
PD Drug
dopamine release, antimuscarinic |
|
|
Term
|
Definition
Bromocriptine
PD Drug
ergot alkaloid,
central dopamine agonist |
|
|
Term
|
Definition
Pergolide
PD Drug
ergot alkaloid,
central dopamine agonist |
|
|
Term
|
Definition
Pramipexole
PD Drug
newer
D2 agonist
early and advanced PD
syncope/bradycardia, hallucinations
COMPULSIVE GAMBLING AND DIRTY SEX! |
|
|
Term
|
Definition
Ropinirole
PD Drug
newer D2 agonist
early and advanced PD
syncope/bradycardia COMPULSIVE GAMBLING AND DIRTY SEX! |
|
|
Term
|
Definition
Entacapone
PD Drug
used to reduce l-dopa and control 'on-off' effects, used in later stages
inhibits peripheral COMT, which increases [dopamine]
increases levodopa side effects |
|
|
Term
|
Definition
Tetrabenazine
Huntington's Disease
catecholamine depleting agent |
|
|
Term
|
Definition
Carbamazepine
An anticonvulsant
Anxiolytic used for Huntington's for anxiety |
|
|
Term
|
Definition
Riluzole
ALS extends survival by months
inhibits glutamate release?
dizziness/somnolence |
|
|
Term
|
Definition
Guanfacine
Tourette's (1st gen)
alpha adrenergic agonists
s/e: sedation, postural hypotension
extrapyramidal side effects possible |
|
|
Term
|
Definition
Clonidine
Tourette's (1st gen)
alpha adrenergic agonists
s/e: sedation, postural hypotension
extrapyramidal side effects possible |
|
|
Term
|
Definition
Risperidone
Tourette's (2nd gen).
somnolence, weight gain, hepato.
less extrapyramidal/tardive dyskinesia.
(this is an antipsychotic) |
|
|
Term
|
Definition
Botulinum toxin A
Tourette's
severe facial tics |
|
|
Term
|
Definition
Selegiline
PD Drug
MAO-B inhibitor (dopamine but not NE) |
|
|
Term
|
Definition
Memantine
Slows progression in Huntington's
NMDA receptor antagonist |
|
|
