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Parisitology
parisitology
46
Pathology
Professional
02/07/2011

Additional Pathology Flashcards

 


 

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Term
Entamoeba histolytic
Definition
intestinal protozoan
-intestinal wall->RBCs (in trophoziote)
-abdominal pain, diarrhea (blood)
-blood->liver->lung->pulmonary abscesses->death
-metronidazole
Term
Giardia lamblia
Definition
intestinal protozoan
-contaminated drinking water, camping, drinking from streams
-adheres to intestinal wall->malabsorption->steatorrhea with horrific odor
-no invasion, no blood
-2 nuclei
Term
Cryptosporidium
Definition
intestinal
-contaminated water, day cares, travelers
-abdominal pain, diarrhea, non-bloody-->severe, protracted diarrhea w/ AIDS
Term
Isospora
Definition
intestinal protozoan
-fecal/oral->diarrhea
-Acidfast
Term
Cyclospora
Definition
intestinal protozoan
-fecal/oral->diarrhea
-Acidfast
Term
Trichomonas vaginalis
Definition
STD
-itching, burning, secretions
-flagellated
-metronidazole
Term
Naegleria Fowleri
Definition
free-living meningitis
-fresh water pool-forced inhalation through nose->cribiform plate->brain->dead within 72 hours of symptoms
-fever, headache, stiff neck, N & V
Term
Acanthamoeba
Definition
free-living meningitis amoeba
-Chronic, granulomatous brain infection with AIDS
-brain tissue shows trophozoite and cyst
-corneal infection with dirty contacts in immunocompetent-->blindness (usually bacteria, can be acanthamoeba)
Term
Balamuthia mandrillaris
Definition
free-living meningitis amoeba
-Chronic, granulomatous brain infection with AIDS
-brain tissue shows trophozoite and cyst
-can cause granulomatous skin lesions
Term
Toxoplasma gondii
Definition
AIDS/Pregnancy
-Raw pork or cat feces
-reactivation in AIDS and primary infection when pregnant (ingest cysts)
-AIDS-fever, lymph/liver/spleen megaly, pneumonia, meningitis, encephalitis (most common CNS disease w/ AIDS)
-chorioretinitis
-Pregnancy-chorioretinitis, blindness, seizures, MR, encephalitis (stillborn if early)
Term
Pneumocystis carinii
Definition
(P.Jiroveci-new fungi name)
-AIDS infection-->invades lungs->severe intestitial pneumonia
-Pneumocystis carinii pneumonia (PCP)->death
-fever, SOB, nonproductive cough, bilateral infiltrates on chest X-ray
Term
Plasmodium
Definition
Malaria
-anopheles mosquito->grow in liver->reproduce in RBC->burst->fever
-P. vivax, ovale-48 hour cycles
-P. malaria-72 hour cycles
-P. falciparum-more continous fever-36-48 hour cycles
-anemia from RBC lysis-falciparum->clumps go to lung, kidney, brain (death from cerebral malaria)
-hepato/splenomegaly-spleen can rupture
-resistance against quinine and chloroquine in falciparum
Term
Babesia
Definition
babesiosis-hemolytic anemia ~maleria
-tick->RBC->fever (no liver)
-mostly cattle
-simlar trophozoite as malaria, fewer numbers and forms cross
-usually asymptomatic->severe w/out spleen
Term
Leishmania
Definition
blood-borne flagellate
-rodents, dogs, foxes->sandfly (nooseeum)
-South/Central America, Africa, middle east
-Sandfly->macrophage->multiplies in LN, spleen, liver, bone marrow
-host immune-cell-mediated (Th1)
-cutaneous, diffuse cutaneous, mucocutaneous,
-visceral (L. donovani and L. chagas)-abdominal pain, distension, low-grade fever, anorexia, weight loss, massive splenomegaly, severe anemia, low WBC, death
Term
Trypansoma brucei
Definition
blood-borne flagellate-african sleeping sickness
-T. brucei rhodiense-east, more sever
-T. brucei gambiense- west
-tsetse fly->blood->LNs and CNS
-hard, red, painful skin lesion->fever, headache, dizziness, swollen LNs, cycles of fevers (weeks at a time)
-daytime drowsiness, difficulty walking, slurred speech, coma, death
-fever caused by VSGs
Term
Balantidium coli
Definition
-ciliated protozoan->balantidiasis
-water with pig feces
-diarrhea
-large, ciliated protozoa in intestine (can be mistaken as seed)
Term
Ascaris lumbricoides
Definition
intestinal nematode
-southern US
-food w/ eggs->intesitines-> lung->cough->lintestines
-mild or asymptomatic GI->severe worm to bile ducts, gall bladder, appendix, liver
-eggs in feces
Term
Nector americanus
Definition
intestinal nematode-hookworm
-soil->penetrate foot->lung->cough->intestines
-diarrhea, abdominal pain, weight loss->sucks blood->iron deficiency anemia
-eggs in feces
Term
Strongyloides stercoralis
Definition
intestinal nematode
-soil->penetrate foot->lung->cough->intestines
-vomiting, abdominal bloating, diarrhea, anemia, weight loss, rash, cough
-autoinfection-potential death with steroids (immunosupressents)->ARDs and organ failure
-LARVA in feces (not eggs)
Term
Trichinella spiralis
Definition
intestinal nematode
-ingest encysted larva on raw pork->intestines->females penetrate and lay eggs in mucosa->blood->organs and muscles->form cysts
-abdominal pain, diarrhea->1 week->fever, muscle ache
-can invade heart and brain
Term
Trichuris trichiura
Definition
intestinal nematode-whipworm
-simple slow life cycle-ingest eggs->intestines->cecum
-abdominal pain and diarrhea
Term
Enterobius vermicularis
Definition
intestinal nematode-pinworm
-ingest egg->cecum->anus to lay eggs
-perianal itching-tape test
-autoinfection with kids
Term
Onchocerca volvulus
Definition
blood/tissue nematode
-filariae live in LN->microfilariae->burrow through tissue->blood and lymph
-allergic rxn to micro and dead
-africa/central/south america
-black fly->skin and subcutaneous tissue->interepithial granulomas
-microfilariae->eye-river blindness
Term
wuchereria convrofti
Definition
blood/tissue nematode-elaphantiasis
-lymphatic infection->chronic leg swelling
-mosquito- southeast asia
-fibrosis around worms clog LN
-draw blood at night-nocturnal periodicity
Term
Dranculus medinensis
Definition
blood/tissue nematode-guinea worm
-ingest intermediate crustacians in water->larva penetrate intestines->female pokes to skin to lay eggs in water
-education stops spread
-N & V, hives, SOB
-use stick to pull out
Term
Schistosomes
Definition
Platyhelminthe (flat worm)
-trematode-fluke
-2nd to malaria
-freshwater-> eggs->larver->snail->mature to cercariae->penetrate skin->venous system->eggs around organ
-molecular mimicry->no immune response to worm (only eggs and cercariae)
-dermatitis, Katayama fever from eggs->fever, weight loss, cough->LN, Spleen, Liver megaly
-chronic fibrosis of organs and BVs
-S. japonicum-intestinal tract->liver
-S. Mansoni-intestinal tract
-S. haematobium- bladder->urine
Term
Taenia solium
Definition
Platyhelminthe (flat worm)-pork tapeworm
-undercooked pork (ingest cysticercus)->minimal symtpoms
-Cysticercosis-ingest eggs->larva hatch in intestines->tissue-encyst (brain and muscle)
-neurocysticercosis-seizures, hydropcephalus, burst/leak-bad
-up to 10% of mexicans, leading cause of seizures
Term
Taenia saginate
Definition
Platyhelminthe (flat worm)-beef tapeworm
-ingest cysticercus larva in beef->relatively benign
Term
Diphyllobothrium latum
Definition
Platyhelminthe (flat worm)-fish tapeworm
-eggs->crustacean->fish->human
-absorbs B12->anemia
Term
Hymenolepsis
Definition
Platyhelminthe (flat worm)-drawf tapeworm
-smallest tapeworm
-ingest eggs->tapeworm
-binds to GI and causes N & V, abdominal pain
Term
Trypanasoma cruzi
Definition
-blood-borne flagellate-chagas disease
-Texas, Mexico, Cental/South America
-rodents, opossums, armadillos->reduvid bug "kissing bug"
-acute-hardened red area (chagoma)->fever, malaise, swollen LNs, CNS and heart
-Intermediate-asymptomatic
Chronic-heart-dilated cardiomyopathy and electrical tachycardia
-megadisease of colon and esphogus-big, poor function, pain->painful swallowing and constipation
Term
Echinococcus granulosus
Definition
-hydatid disease
-ingest eggs->larva->intestines->tissue->"hydatid" cyst inlung, brain, kidney, and LIVER
-dog and sheep intermediate
Term
Entamoeba hartmanni
Definition
-looks like E. histolyitica, but smaller
-has 1-4 nuclei and smooth chromatin
Term
Entamoeba coli
Definition
-looks like E. histolytica, but has 1-8 nuclei and lumby-bumpy chomatin
Term
E. nana
Definition
similar to E. hystolyica, but with thick chomatin in center of nucleus
Term
I. Butchlii
Definition
-similar to E. histolytica, but with thick chromatin and large glycogen deposit
-stains with iodine
-may be pathogenic with AIDS
Term
D. fragilis
Definition
-similar to E. hitolytica, but dinuclei
-pathogen->diarrhea
-hangs out with pinworm
Term
Clonorchis sinensis
Definition
-egg->water->snail->circonia->fish->eat raw fish
-go to liver->bile duct->caused fibrosis
Term
Panagonimus westermani
Definition
egg->water->snail->circaria->crab->eat raw crab
-lung->inflammatory rxn
Term
Loa loa
Definition
-eyeworm
-fly->goes to service of eye->does not cause blindness
-blood->under conjuctiva
Term
Dirofilaria immitus
Definition
dog heartworm
Term
Dibothriocephalus latus
Definition
-egg->water->custacean->fish
-eat nova,locks, uncooked freshwater fish
-eats B12
-dorsal column of spinal cord->propioception->weird gate
Term
Anisakiasis
Definition
-egg->water->fish (cold salt water-makaral, tuna)
-raw sushi
-N & V 2 hours after you eat->stick to GE junction->scope and remove
Term
Ciguatera
Definition
-not a parasite
-accumulation of natural toxins-dinoglagellate algae and gambierdiscus toxicus
-grouper, amberjack, baracuda
-Don't eat big fish
-neurotoxin->weird parastesis
Term
Chilomastix mesnili
Definition
mimic giardia, non pathogen
-uninuclei, polar flagella, safety pin
Term
Ancylstoma duodenel
Definition
non-human hook worm
-cutaneous larval migrans
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