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Parasitology V
worms
56
Medical
Professional
04/27/2009

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Term
eat undercooked pork containing cysted larvae
Definition
trichenella spiralis (trichinosis)
Term
excystation ocurs in small intestine as larvae penetrate mucosa then develop into adults and spread to striated muscles
Definition
trichenella spiralis
Term
infectious load for trichinosis
Definition
<10 is asymptomatic; >100 is significant; 1000+ can kill you
Term
"splinter" hemorrhages under nails; fever, myalgia and marked eosinophilia
Definition
Trichenella spiralis
Term
tx of trichenella spiralis
Definition
nothing for encysted larvae; can treat adult GI phase with albendazole or mebendazole; give anti-inflammatories in severe infections
Term
accidental infection from dogs/cats; ingestion of eggs that hatch in small intestine and then migrate to various tissue
Definition
Toxocara canis or cati
Term
mostly asymptomatic but heavy burdens can produce red eye and visual impairment
Definition
Toxocara canis
Term
serology w/ enzyme linked assays + eggs in pet feces
Definition
Toxocara canis
Term
Tx of Toxocara canis/cati
Definition
albendazole but need anti-inflammatory treatments; also don't eat cat poop
Term
extraintestinal infections caused by vector-borne, threadlike worms
Definition
filariasis
Term
lymphatic filariasis found in tropical areas
Definition
Wuchereria bancrofti
Term
Lymphatic filariasis found in Southeast Asia
Definition
Brugia malayi, timor
Term
lymphatic filariasis life cycle
Definition
mosquito bite, migrates to lymphatics, develops into adults, then microfilariae are released into blood stream (diagnostic)
Term
widespread lymphadenopathy w/ microfilariae in blood
Definition
lymphatic filariasis (Wuchereria and Brugia)
Term
tx for lymph filariasis
Definition
early infections treat wtih diethylcarbamazine; chronic is resistant to it
Term
Africa, blackfly bite; present with skin nodules and ocular lesions
Definition
Onchocerca volvulus (river blindness)
Term
dx of Onchocerca volvulus
Definition
microfilariae in skin or nodules
Term
Loa loa
Definition
loaisis, rain forests of Africa, Chrysops fly; transient "calabar swellings" on extremities w/ microfilariae in muscle, skin and eyes
Term
Dirofilaria immitis
Definition
dog heartworm; causes "coin lesion"
Term
Dracunculus medinensis
Definition
drinking water with contaminated Cyclops microcrustacean and larvae
Term
Tx of Onchocerca volvulus
Definition
Ivermectin
Term
flat, leaf-shaped worms that are hermaphrodites (usually), humans are definitive host w/ intermediate host usually being snails
Definition
trematodes (flukes)
Term
snail fever; extremely common infections esp in Mexico and caribbean (cruise?)
Definition
Schistosomiasis
Term
life cycle of schistosomes
Definition
eggs excreted by humans and hatch in fresh water forming miracidia. these miracidia penetrate snails and form sporocysts then cercariae (infectious) inside which are released; cercariae penetrate human skin and lose tails to become schistosomulae which enter circulation and mature in liver; they eventually mate and move to venules of bowel,rectum or bladder --> bisexy worm
Term
Schistosoma mansoni
Definition
Africa, caribbean, SA --> inf mes vein
Term
Schistosoma japonicum
Definition
far east --> sup mes veins
Term
Schistosoma hematobium
Definition
Africa/Nile --> Urinary plexus/veins
Term
few weeks after exposure have fever, cough, abdominal pain, rash, liver granuloma and urinary symptoms
Definition
acute schistosomiasis (Katayama's fever)
Term
granulomatous inflammatory response, fibrosis and obstructino
Definition
chronic schistosomiasis; due to increasing load
Term
Swimmer's itch; swimming in the great lakes
Definition
skin rash associated with schistosomal penetration but not bad as species cannot infect humans and end up dying
Term
dx for Schisosomiasis
Definition
detection of eggs in feces or urine (hematobium)
Term
tx for schisto
Definition
Praziquantel for all species; Metrifonate (hematobium) and oxamniquine (mansoni)
Term
larval migration and growth in lung cauing rusty sputum (blood/eggs); traveled to asia, africa or latin america and something involving water
Definition
Paragonimus westermani, the lung fluke; treat with Praziquantel
Term
SouthEast Asia; something about the water; abdominal pain and diarrhea
Definition
Fasciolopsis buski, the giant intestinal fluke; treat with Praziquantel
Term
hepatomegaly, biliary obstruction, water involvement
Definition
Fasciola hepatica, the liver fluke; treat with bithionol (only weird one)
Term
China, eat undercooked freshwater fish, hepatic problems
Definition
Opisthorchis sinesis, the chinese liver fluke; treat with Praziquantel
Term
flat, segmented worms that are all hemaphrodites; have scolex w/ hooklets and suckers for attachment; generally found in intestine
Definition
cestodes or tapeworms
Term
dx for tape worms
Definition
proglottid segments in the eggs
Term
pork tapeworm
Definition
Taenia solium
Term
beef tapeworm
Definition
Taenia saginata
Term
ingestion of eggs can lead to hatching in stomach, development of oncospheres and migratio to muscles and cause widespread problems
Definition
cysticercosis (only T. solium)
Term
treatment for tapeworms
Definition
praziquantel, paromycin or quinacrine
Term
cystic echinococcosis
Definition
E. granulosus (most common)
Term
alveolar echinococcosis
Definition
E. multilocularis
Term
polycystic echinococcosis
Definition
E. vogeli
Term
life cycle of tapeworms
Definition
ingestion of larval cysterceri from meat; develops in small instestine; eggs/proglottids passed in feces and can infect animals
Term
Canids are definitive hosts; human exposure to eggs in feces
Definition
hyatidosis due to Echinococcus
Term
eggs hatch and form oncospheres which migrate but prefer lungs; oncosphere develops into slow growing cyst
Definition
E. multilocaris
Term
dx and tx for hyatidosis
Definition
MRI/CT scan; surgical removal + mebendazole
Term
largest parasite of humans; eggs in freshwater hatch into larvae that are eaten by small crustaceans (proceroid stage); crustacean eaten by fish (get plerocercoid stage); humans eat them and adults develop in small intestine
Definition
Diphyllobothrium latum, the fish tapeworm
Term
tx of D. latum
Definition
niclosamide, praziquantel; give B12 supplementation
Term
dwarf tapeworm
Definition
hymenolepsis nana
Term
rat tapeworm
Definition
hymenolepsis diminuta
Term
most common tapeworm in North america
Definition
Hymenolepsis nana
Term
H. nana
Definition
rats and beetles are intermediate hosts; worms then live in human small intestine
Term
H. diminuta
Definition
rare in humans and live in rodents and beetles
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