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Parasitology Exam 2
GGC - Cestodes, Nematodes, Acanthacephalans, Nematomorphs
108
Biology
Undergraduate 3
09/23/2013

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Term
Cestoidea
Definition
Tapeworms. Adults live in intestines of all vertebrates, lack digestive system
Term
Body form of adult cestodes
Definition
Scolex, neck, strobila
Term
Scolex
Definition
"head": holdfast organs, suckers hooks spines tentacles glands or a combination
Term
Pseudoscolex
Definition
Folds of strobila
Term
Polyzoic
Definition
Multiple proglottids
Term
Monozoic
Definition
single proglottid
Term
Strobila
Definition
linear series of proglottids
Term
Strobilation
Definition
new proglottids form near neck region; older proglottids toward posterior end mature sexually then copulation; detach and pass intact with feces
Term
Selfing
Definition
sexually mature proglottid fertilizes itself and becomes gravid
Term
Apolysis
Definition
detach then break up releasing eggs
Term
Pseudoapolysis
Definition
eggs passed through uterine pore, proglottid detach after senility
Term
Hyperapolysis
Definition
detach prior to sexual maturity, mature in gut
Term
Craspedote proglottid
Definition
posterior portion of the proglottid (i.e., velum) overlaps the anterior portion of the next proglottid
Term
Acraspedote proglottid
Definition
the posterior portion of the proglottid does not overlap the anterior portion of the next proglottid
Term
Acetabula
Definition
muscular cup shaped or oval, typically 4 on scolex
Term
Bothridia
Definition
muscular, project from scolex, some leaf like, typically in groups of 4 on scolex
Term
Bothria
Definition
2-6 (typically 2) shallow grooves or pits on scolex
Term
Rostellum
Definition
in acetabulate worms, dome shaped protrusion, may be armed with 1-2 rows of hooks, or may be retracted into scolex and unarmed
Term
Lots of stem cells are located in what region of a cestode?
Definition
neck region below the scolex
Term
Cestode tegument: major differences from trematode tegument?
Definition
membrane forms microtriches to increase absorptive area, cover entire worm including scolex
Term
Filamentous microtriches
Definition
thin in diameter, resembling a thread
Term
Palmate microtriches
Definition
angles between tines partly filled in to form a broad flat surface (ex. moose antlers)
Term
Glycocalyx
Definition
layer of carbohydrate macromolecules associated with membrane of microtriches
Term
Calcareous Corpuscles
Definition
calcium and magnesium carbonates, possibly function to buffer against organic acids produced, or are an excretory product, who knows.
Term
Nervous system complexity of cestodes depends on...
Definition
scolex arrgmt. Simplest are worms with bothria; more complex with acetabula and bothridia
Term
Excretory system of cestodes?
Definition
2 pairs of excretory canals run length of strobila, joined in scolex, and posteriorly joined to form excretory bladder. Transverse canals join lateral canals in each proglottid. Flame cells in parenchyma feed into canals. excretory ducts with microvilli.
Term
Osmoregulation of cestodes?
Definition
Not so much...they are osmoconformers.
Term
Reproduction of cestodes...
Definition
mostly monoecious. Each proglottid 1 set of each sex but variation.
Term
Asynchronous Sexual Maturity (ASM)
Definition
In cestodes, protoandry (male organs mature 1st) and protogyny (female organs mature 1st).
Term
Egg shell formation in cestodes...
Definition
completed from within egg by vitelline cells and zygote (as opposed to trematodes)
Term
Psudophyllidean type egg
Definition
covered with thick capsule (sclerotin); multiple vitelline cells associated with zygote
Term
Dipilidium type egg...
Definition
thin capsule and embryophore. 1 or 2 vitelline cells with zygote
Term
Taenia type egg...
Definition
thin capsule but thick embryophore (ability to withstand dry environment for terrestrial life cycle). 1 or 2 vitelline cells with zygote
Term
Lifecycle of cestodes
Definition
most require 2 hosts, aquatic tapeworms often 3
Term
cestodes can release up to how many eggs?
Definition
several million
Term
Where are adult cestodes found in vertebrates?
Definition
the intestine
Term
Oncosphere
Definition
formed by embryogenesis in cestode egg. Cestode equivalent to miracidium in trematodes
Term
Parenteral site infection
Definition
oncosphere of cestode infecting a site outside of the intestinal track
Term
Metacestode
Definition
generic term for juvenile tapeworm; metamorphose from oncosphere
Term
enteral site
Definition
site in the intestine where the adult tapeworm infects once developed from a metacestode
Term
Hexacanth
Definition
type of oncosphere with 6 hooks under muscular control (lifecycle involves terrestrial)
Term
Coracidium
Definition
type of oncosphere with 6 hooks, ciliated, free swimming
Term
Lycophora
Definition
type of oncoshpere with 10 hooks, ciliated
Term
Procercoid
Definition
larval form found in the first intermediate host of many Cestoda with aquatic life cycles
Term
Plerocercoid
Definition
last larval form found in the second intermediate host of many Cestoda with aquatic life cycles (has scolex and elongation of strobila)
Term
Cysticercous
Definition
type of metacestode; a bladder worm, larva of cestode from which a single scolex buds internally
Term
Cysticercoid
Definition
a solid-bodied larva of a cestode (ex: hymenolepis diminuta)
Term
Schistocephalus solidus
Definition
plerocercoid distends body of small fish and changes behavior to be eaten easily by heron def. host
Term
Metacestodes effects on host
Definition
parasite induced trophic transmission; increase transmission to next host by: change behavior, physiology, or morphology
Term
Hymenolepis diminuta effects in beetles
Definition
longer life span/reduced fecundity; attracted to predator's poop smell (rat)
Term
Stimulus for metacestode strobilation in def. host
Definition
host digestive enzymes (pepsin/trypsin), temperature, contact with host substrate
Term
cestode preferred diet in def. host
Definition
polysaccharides because complex and not as quickly taken up by host's gut mucosa
Term
Adult cestode metabolism type
Definition
Facultative anaerobes: Kreb cycle and electron transport chain not important
Term
Polyzoic
Definition
multiple proglottids
Term
Monozoic
Definition
single proglottid (looks like trematode but no ceca)
Term
Order Pseudophyllidea
Definition
scolex with 2 bothria (grooves), coracidia (ciliated oncosphere). Heteroxenous lifecycle usually involves crustaceans and fish. 10-30 ft long
Term
Order Cyclophyllidea
Definition
scolex with 4 acetabula (muscular suckers), rostellum (protrusion of scolex) present or absent, armed or unarmed
Term
Hexagonoporus physeteris
Definition
in whales, grow more than 130 ft long, 4-14 sets of genitalia per proglottid, 45,000 proglottids!
Term
Family Diphyllobothriidae
Definition
broad fish tapeworms, not host specific, species difficult to identify. Release up to 1 million eggs/day! Pseudoanapolytic: release long segments of SPENT proglottids.
Term
Diphyllobothrium latum
Definition
(Latum: Latin for broad); found in humans, canines, felines, mustelids, pinnipeds, bears. less common in humans but endemic in Scandinavia, Russia. About 10m length.
Term
Diphyllobothrium dendriticus
Definition
holartic distribution (both old/new world); about 1m length.
Term
Diphyllobothrium spp. lifecycle
Definition
eggs w/operculum, coracidia hatch and swim erratically after days/weeks, procercoid in paratenic hosts (copepod/small fish), plerocercoid in larger fish, egg production 7-14 days in def. host
Term
Diphyllobothrium spp. Pathology
Definition
many cases asymptomatic, abdominal pain, diarrhea, nausea, weakness. Pernicious Anemia: 80-100% vitamin B12 absorbed by worm needed for host's RBC production. Don't eat raw fish!
Term
Sparganosis
Definition
infection with larval Pseudophyllideans; plerocercoids (Spargana) invade human tissue from:
-accidental ingestion of copepods (procercoid)
-eating poorly cooked vertebrates (plerocercoid)
-using freshly killed frog as treatment for skin ulcers or inflammation of eye/vagina.
--treatment usually surgery
Term
Diphyllobothrium mansonoides
Definition
In N. America; cat definitive host; plerocercoid can live up to 10 yrs in humans
Term
Spargana
Definition
Psudophyllidean plerocercoids; can sometimes reproduce asexually by budding
Term
Order Cyclophyllidea
Definition
Scolex with 4 muscular acetabula (along with Order Proteocephalata). Characteristic compact post ovarian vitelline gland. Armed rostellum. Usually small worms. In birds and mammals.
Term
Family Taeniidae
Definition
Largest tapeworms in Order Cyclophyllidea; medically important; morphology similar (except Echinochoccus spp); armed not retractable rostellum often present; metacestodes various types of bladder worms.
Term
Taenia saginata
Definition
beef tapeworm; humans only serve as a def. host; ~30 ft, 2000 proglottids; unarmed scolex, no rostellum; no uterine pore: only way for eggs to get out is proglottid rupture or release into env.; embryophore surrounds oncosphere/protects from dessication
Term
Taenia saginata lifecycle
Definition
motile proglottids out; hexacanth larvae viable up to 5 months; eaten by cattle; hexacanth hatch, invade circulatory sys; cysticercous metacestode in muscle.
--Infection by ingesting raw/undercooked infected meat
Term
Taenia saginata Pathology
Definition
mostly asymptomatic; dizziness, diarrhea, nausea, pain.
Term
How to tell T. saginata from T. solium?
Definition
depends on scolex and proglottid morphology; fresh proglottid differ in number of uterine branches(saginata more branched)
Term
Taenia Solium lifecycle
Definition
human infected by eating raw/undercooked pork/cat/dog. flies can spread eggs. cysticerci in muscles and organs of pigs. evagination, attachment, pathology of adult worm similar to saginata, except it can kill because migrates to brain sometimes. Causes cysticercosis.
Term
Cysticercosis
Definition
From ingesting eggs of adult T. solium. Mexico, Latin America, Sub-Saharan Africa, India, China. cysticerci develop in human as an int. host. Potential infection due to fecal contamination or rupture of gravid proglottid. Infects subcutaneous tissues, then eyes, brain, muscle, heart, liver, lung. Cellulose and Racemore forms: host produces fibrous capsule around worm up to 20cm diameter. down modulate immune sys
Term
Echinococcus granulosus
Definition
smallest in family (3-6mm). scolex, rostellum armed 2 rows hooks, short neck, 3 proglottids (immature,mature,gravid). 2 host lifecycle: carnivore def. and herbivore int. Causes cystic echinococcosis from horse/pig or sheep/cattle (sheep strain infects humans)
Term
Echinococcus granulosus lifecycle
Definition
eggs ingested thru grazing. Herbivore int. host. Hatching, migration of oncosphere to lung and liver. Metamorphose to Unilocular Hydatid metacestode. Cyst develops and produces thousands of protoscolices that attach to villi of carnivore def. host (usually a canid but human can be infected from embryonated egg in organs of meat or in feces)
Term
Unilocular Hydatid cyst
Definition
outer noncellular layer, inner nucleated germinal layer: produces brood capsules(daughter cysts) which produce protoscolices. Cyst often encapsulated by host immune system at work. cyst may become huge, rupture can cause sudden death by anaphylactic shock. treatment surgery and formalin, or Albendazole if inoperable
Term
Echinococcus multilocularis
Definition
smaller than E. granulosus (up to ~4mm). Boreal distribution. Def. hosts: fox,coyote,cat,dog. Int. hosts: small rodents. Metacestode differ from granulosus: Cyst is Alveolar Hydatid (branched, ruptures more easily). Alveolar echinococcosis, not common but hard to operate on.
Term
Family Dilepididae, Dipylidium caninum
Definition
more common in children. scolex w/4 acetabula. retractable armed rostellum. Proglottid(size of rice grain) 2 sets of male/female genitalia, 2 genital pores. Eggs released in capsules, eaten by larval fleas, cysticercoid in adult flea, eaten by def. host.
Term
Order Proteocephalata
Definition
all parasites of freshwater fishes, amphibians,reptiles. 4 acetabula. lifecycle involves copepods.
Term
Proteocephalus ambloplitis
Definition
Procercoid--Plerocercoid stages. Bass are def. host. Paratenic hosts common.
Term
Order Caryophallidea
Definition
Monozoic tapeworms of freshwater fish. Scolex unarmed w/loculi (shallow depression in scolex). 1 set of m/f genitalia. Neotenic plerocercoids: larval stage that acquires adult characteristics but body is still in larval stage. may look like trematode, Scolex but no ceca=tapeworm, not trematode.
Term
Family Hymenolepidae
Definition
Diagnostic character of group: 1-4 testes
Term
Hymenolepis nana
Definition
*most common human tapeworm*. small (40mm) and cosmopolitan. Pathology rare. UNIQUE lifecycle among cestodes: monoxenous, only needs us to infect ourselves again from contaminated food, water,or hands.
Term
Hymenolepis diminuta
Definition
parasitic in rats but can infect humans
Term
Family Trichuridae
Definition
Whipworms. Lots of spp infect mammals
Term
Trichuris trichiura description
Definition
infects humans. 30-50mm long whiplike body. mouth armed, small buchal cavity. Stichosome--long and slender esophagus surrounded by stichocytes. Single gonad(both sexes). Single spicule in males. Eggs unembryonated with 2 opercula. Excretory sys lacking.
Term
Trichuris trichiura lifecycle/pathology
Definition
~800 mil infected. DIRECT LIFECYCLE: embryonation in soil 21 days (moisture/shade), larvae hatch, penetrate gut mucosa, posterior end grows into lumen, anterior embedded in mucosa. Heavy infections(>100 worms) dysentery, anemia, rectal prolapse.
Term
Family Trichinellidae
Definition
Trichinella spp.(T. spiralis). Cosmopolitan. Small nematode parasite (male<2mm, fem<4mm). Most widespread and important human parasite
Term
Trichinella spiralis
Definition
Most widespread/important human parasite. ovoviviparous: larvae develop in egg and hatch live larvae. UNIQUE LIFECYCLE: same host can serve as both def. and int. host (like T. solium) by infecting self. Adults are intramulticellular parasites, juvenile parasitic in nurse cell.
Term
Trichinella spiralis Pathology
Definition
3 stages:
worms migrate thru intestinal epithelium, then Juvenile migration to muscles, then Nurse cell formation. Inflammation results in nausea,vomiting,diarrhea,sweating,respiratory issue,fever within a week. Blood vessel damage, inflammation of organ tissues(brain,eye,heart). ~90% cases asymptomatic or mild.
Term
Strongyloides stercoralis description
Definition
infects other primates,cats,dogs et al. Small worms parasitic in intestine. Adult females ~2mm. Has both parasitic and free living cycle. Parthenogenesis. No males in parasitic form. Can alternate between parasitic and freeliving cycles. Soil contamination and transmammary.
Term
Strongyloides stercoralis lifecycle
Definition
3 different lifecycles...
-Autoinfection: Rhabditiform larvae in large intestine become filariform (infective) larvae and penetrate mucosa and follow infective cycle
-Homogonic: Rhabditiform excreted in stool and develop into filariform
-Heterogonic: Rhabditiform freeliving in soil, mate, eggs fertilized by female worms, Rhabditiform hatch and develop into filariform and penetrate host's skin
Term
Strongyloides stercoralis Pathology
Definition
3 stages...
-Invasive: filariform penetrate skin,cause swelling and itching
-Pulmonary: wheezing cough, burning sensation in lung mistaken for asthma
-Intestinal: autoinfection of filariform migration thru gut mucosa, pain,tissue destruction, may be fatal
Term
Necator americanus description
Definition
Hookworm. Adults in small intestine(12-20mm). Feed on blood. Eggs passed in feces hatch in soil. Rhabditiform feed on bacteria. Filariform Juveniles burrow thru skin. Migration-blood-lungs-intestine.
Term
Necator americanus Pathology
Definition
Anemia. Mental retardation in children.
Term
Ascaris lumbricoides description
Definition
Human roundworm. Found in 25% world's pop. Females 200,000 eggs/day. Pathology: Juveniles--pneumonia, Adults--Abdominal problems, blockage
Term
Family Oxyuridae, Enterobius vermicularis
Definition
Pinworms. Most common helminth parasite in the U.S.(30% in children). Bulbous pharynx. Live in L. intestine and cecum, don't migrate so pathology absent. Females migrate to anus to lay eggs. Haplodiploidy.
Term
Family Onchocercidae
Definition
Filarial Nematodes. Females release live microfilariae in blood and lymph. 8 spp parasitize humans(tropics). Insect vectors.
Term
Wuchereria bancrofti
Definition
causes Elephantiasis. Adults in lymphatic system cause inflammation and obstruction. Microfilariae picked up by mosquito in blood meal, develop and infect new host when mosquito bites uninfected individual
Term
Dirofilaria immitis
Definition
Dog heart worm. Most common filarial nematode in U.S. Insect vector=mosquito. Found dwelling more on right side of heart because less pressure and thinner wall
Term
Drucunculus medinensis
Definition
Fiery serpent. Humans--copepods. Filter straw success story in Africa.
Term
Phylum Nematomorpha
Definition
Horsehair worms. ~300 spp. Parasites of arthropods (beetles,crickets). 3-4cm to 3m length. 2 Groups: Nectonematida and Gordiida. Most in Gordiida--freshwater, semiterrestrial and terrestrial hosts. Rare human cases.
Term
Horsehair worms
Definition
Larvae small and different from adults. Preseptum--has lots of hooks
Postseptum--with pseudointestine, cyst wall formation. Lifecycle: adult mate in fresh water or damp soil, lay eggs in water in long strings. Larvae encyst on vegitation.
Term
Phylum Acanthacephala
Definition
Spiny headed worms. Rare compared to other helminths. Infect intestinal tract of all vert. Can cause pathology. Related to rotifers!
Lacunar system possibly for hydraulics of proboscis.
Term
Acanthor
Definition
Acanthacephala larvae. Infective to arthropod, hooks with associated muscles (rostellum)
Term
Acanthella
Definition
organ system develop, synonymous to metacercariae in trematodes
Term
Cytacanth
Definition
in cyst, infective stage, end stage of development in arthropod. Synonymous to cercariae--alter behavior in host, swimming behavior and phototaxis
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