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Parasitology Exam 2
Apicomplexans, Schistosomes, Fasciola
11
Biology
Undergraduate 4
03/31/2011

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Term
Eimeria tenella
Definition
Only in chickens, causes bloody cecum. High morbidity, high mortality.
Niche: ceca.
Host defenses: shed cells, fecal express, macrophages
Infective: sporulated oocysts in feed or water
Sporogony occurs OUTSIDE of host
Term
Isopora belli (aka - Cystoisospora belli)
Definition
Only Isopora in humans, located in tropics.
Causes severe diarrhea, fever, cramps.
Bad in immunocomp (can go extraintestinal)
Niche: small intestine, host must consume SPORULATED oocyst
Dx: Oocysts in fecal sample
Rx: Septra
Term
Cyclospora cayetanensis
Definition
"Emerging" - fairly new, 1990 in USA Niche: Small intestine (jejunum) Explosive, watery diarrhea, cramping, possible vomiting, alternates with constipation, self-limiting. Sources: Contaminated food (raspberries, strawberries, meclun lettuce, basil) and water. Sporogony outside host. Oocysts small with 2 sporocysts with 2 sporozoites each (4 total). Hard to see in unstained fecal matter, easier to see with acid-fast stain (will be reddish) Dx: Microscopy of acid-fast stained fecal smear Rx: Septra
Term
Cryptosporidium parvum
Definition
Worldwide zoonosis of vertebrates. At risk; immunocomp (infants, elderly). Direct life cycle.
Sporulated oocyst ingested, sporozoites released in sm. intestine & attach to epithelial cells (create unique extracytoplasmic "intracellular environment"), merogony --> gametogony. Make thick and thin walled oocysts (thick pass, thin rupture and reinfect). Internal sporogony. Diarrhea, abdominal pain, nausea, vomiting. 10-12 days.
Transmission: Water, food-borne, day care center, lab techs.
Dx: Acid-fast stain of fecal sample, oocysts larger than Cayetanensis. ELISA kits
Rx: Anilia (not for immunocomp). Immunity develops.
Term
Diarrhea of more than two weeks?
Definition
Cryptosporidium parvum or Giardia lamblia.
Term
Rx for Toxoplasma gondii
Definition
DOC: Spiramycin (fetal toxo)
For Immunocom: Daraprim, folic acid antagonists
Term
Malaria Treatment
Definition
Assume falciparum until proven otherwise;
Treat immediately with Atovaquone and Proguanil, Mefloquine. If severe, Quinine with doxycycline or clindamycin.

If not falciparum, you can use chloroquine.
Term
Babesia vectors. B. bigemina, B. microti, B. divergens, B. canis
Definition
Bigemina: Boophilus annulatus
Microti: Ixodes scapularis (also carries Brrelia burghdorfi -- lyme disease)
Divergens: Ixodes ricinus
Canis: Rhipicephalus sanguineus, Dermacentor variabilis
Term
Schistosoma haematobium
Definition
Urinary bladder veins = niche
Terminal spine on egg
Snail host: Bulinus sp.
Term
Schistosoma mansoni
Definition
Inferior mesenteric veins (large intestine)
Eggs with lateral spine
Intestine and liver disease
Snail: Biomphalaria sp
Term
Schistosoma japonicum
Definition
Superior mesenteric veins (small intestine)
least host specific (zoonosis, has reservoirs in cattle and water buffalo)
Intestine and liver disease
Eggs: rudimentary/no spine
Snail: Oncomelania
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