Term
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Definition
Trade name: Narcan
Classification: narcotic antagonist, Pregnancy class c
Actions: blocks the effects of both natural and synthetic narcotics and may reverse respiratory depression
Indications: narcotics overdose: morphine, dilaudid, Fentanyl, Demerol, paregoric, methadone, heroin, percodan, tylox. Synthetic narcotic overdose: nubain, Stadol, talwin, darvon. Coma of unknown origin. OD w/ respiratory depression
Contraindications: hypersensitivity, non-narcotic induced respiratory depression
Side effects: N/V, reoccurrence of pain, seizure
Dose/Route: 0.4-2 mg IV, IM, IN repeated in 2-3 min as needed up to 10 mg. Peds 0.01 mg IV, IM, IN repeated in 2-3 min as needed up to 10mg
Onset: within 2 min; Duration: 20-60 min; Half life: 30-60 min |
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Term
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Definition
Trade name: Morphine
Classification: narcotic analgesic, opiate agonist, schedule II, Pregnancy class C
Actions: potent analgesic and sedative that causes some vasodilation reducing venous return and reduced myocardial O2 demand; binds to opiate receptors, causes histamine release.
Indications: moderate to severe pain, MI, pulmonary edema, reducing preload (CHF pt’s)
Contraindications: hypersensitivity to opiates, undiagnosed head or abdominal injury, hypotension, volume depletion, acute bronchial asthma, COPD, severe respiratory depression, pulmonary edema due to chemical inhalation
Side effects: altered LOC, respiratory depression, dizziness, hypersensitivity
Dose/Route: 0.1 mg/kg (2-10 mg standard for an adult) IV, SC, IM
Onset: about 1 min; Duration: 2-4 hours; Half life: 2-3 hours |
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Term
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Definition
Trade name: Versed
Classification: sedative, benzodiazepine, anticonvulsant, Class IV, Pregnancy class D
Actions: short acting benzodiazepine with CNS depressant, muscle relaxant, anticonvulsant, and anterograde amnestic effects
Indications: induce sedation for cardioversion or intubation, acute anxiety states, seizures, stimulant OD (cocaine)
Contraindications: hypersensitivity, narrow angle glaucoma, shock, coma, acute alcohol intoxication
Side effects: drowsiness, hypotension, amnesia, respiratory depression
Dose/Route: 0.1 mg/kg IV, seizure usually 5 mg, sedation usually 1-2.5mg; 0.2 mg/kg IM/IN, seizure usually 10 mg, sedation usually 5 mg. Peds 0.05-0.2 mg/kg IV
Onset: 60-90 sec; Duration: 15-30 min; Half life: |
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Term
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Definition
Trade name: Sublimaze
Classification: narcotic analgesic (opiate agonist), schedule II, Pregnancy class B
Actions: potent synthetic narcotic analgesic similar to morphine and meperidine but with a more rapid and less prolonged action. CNS depressant; Causes endorphin release (feeling of happy)
Indications: severe pain, adjunct to RSI, maintenance of analgesia
Contraindications: MOAI within 14 days, myasthenia gravis, shock, severe hemorrhage, undiagnosed abdominal pain
Side effects: dizziness, LOC/AMS, bradycardia, N/V
Dose/Route: 1 mcg/kg (50-100 standard for an adult) SIVP, 2 mcg/kg IN Peds: 2.0 mcg/kg slow IV
Onset: about 2 min; Duration: 30-60 min; Half life: 2-3 hours |
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