Term
Classic regimen for coronary artery disease/angina pectoris |
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Definition
daily ASA
sublingual NTG prn for pain
daily BB
statin (if increased LDL) |
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Term
DOC for acute management of acute symptoms of angina |
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Definition
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Term
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Definition
SBP < 90
right ventricular infarction
use of viagra (sildenafil) & other PDE-5 inhibitors |
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Term
1st line drug for chronic treatment or coronary artery disease |
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Definition
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Term
MCC of coronary artery disease |
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Definition
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Term
substernal chest pain often brought on by exertion (d/t decreased supply & increased demand) |
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Definition
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Term
what is the most useful noninvasive screening tool for CAD/angina pectoris? |
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Definition
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Term
what is the definitive diagnosis tool for CAD/angina pectoris? |
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Definition
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Term
Initial stress test of choice for most patients w/ normal resting ECG |
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Definition
treadmill test
DOESNT assess region of ischemia |
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Term
MC used to test puts w/ baseline ECG abnormalities |
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Definition
radionuclide myocardial perfusion imaging (MPI)
DOES identify regions of ischemia
Adenosine or Dipyridamole (Persantine) |
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Term
CI to radionuclide myocardial perfusion imaging (MPI) |
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Definition
asthmatics (causes bronchospasm) |
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Term
Stress testing done in patients unable to exercise |
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Definition
Pharmacologic stress testing
Adenosine or dipyridmaole
vasodilators preferred with MPI
caution: avoid vasoconstrictors 24h prior |
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Term
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Definition
usues dobutamin
used in pts w CI to vasodilators or w/ recent vasoconstrictor use
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Term
Revascularization techniques for management of angina |
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Definition
1. PTCA (percutaneous transluminal coronary angioplasty)/ PCI (Perc coronary intervention)
2. CABG (coronary artery bypass graft) |
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Term
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Definition
1 or 3 vessel dz NOT involving main left coronary artery + normal or near normal left ventircular function
combo of ASA + clopidogrel (Plavix) used after |
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Term
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Definition
left main coronary artery disease, symptomatic 3 vessel dz, left ventricular ejection fraction < 40% |
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Term
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Definition
ARMS rest
Aortic regurg, Mitral stenosis |
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Term
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Definition
Apple Pies Taste Mmmmm
Aortic : R 2nd ICS
P : L 2nd ICS
Tricuspd: L 4th ICS (erbs @ 3 ICS)
Mitral : 5th ICS (mid clavicular line) apex |
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Term
radiation of aortic stenosis |
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Definition
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Term
radiation of mitral stenosis |
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Definition
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Term
radiation of aortic regurg |
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Definition
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Term
radiation of mitral regurg |
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Definition
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Term
_____ murmurs are intensified when patient sits up and leans forward |
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Definition
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Term
_____ murmurs are intensified when patient lays on left side (decubitus position) |
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Definition
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Term
Increased venous return INCREASES _____ |
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Definition
ALL MURMURS/ opening snap
ie squatting, leg raise, laying down
****exceptions: decreased murmur of HCM & delayed ejection click (decreased prolapse/shorter murmur duration) of MVP |
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Term
Inspiration increases venous return on the right side---? |
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Definition
increases ALL murmurs/opening snap on the R side (decreased ejection click R side)
right sided murmurs heard best w/ inspiration |
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Term
expiration increases venous return on left side |
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Definition
increase all murmurs/opening snap on the L side
(delayed ejection click on the L side)
left sided murmurs best heart after maximal expiration |
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Term
Handgrip increases after load (by compressing arteries of UE) leading to decreased LV emptying (decreased forward flow & increased backward flow) |
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Definition
AR, MR, increases with hangrip d/t backward flow
MS increases d/t to afterload |
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Term
amyl nitrate decreases afterload (direct arteriolar vasodilator) leading to increased LV emptying (increases forward flow & decreases backward flow of blood |
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Definition
AR, MR decreases with amyl nitrate
(this is why afterload reducers like ACEI are used in tx) |
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Term
CXR classic triad : egg on a string appearance of heart, increased pulmonary vascular congestion, mild cardiomegaly |
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Definition
transposition of the great vessels |
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Term
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Definition
ventricular septal defect |
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Term
Harsh holosystolic murmur @ L sternal border, LVH + RBH (biventricular hypertroph) |
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Definition
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Term
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Definition
35% close spontaneously
sx
diuretic
digoxin early |
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Term
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Definition
LV outflow obstruction --> fixed CO
increased afterload --> LVH |
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Term
causes of aortic stenosis |
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Definition
degeneration >70
congenital <70
rheumatic fever |
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Term
clinical manifestations of aortic stenosis |
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Definition
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Term
systolic "ejection" crescendo-decrescendo @ RUSB later peaking murmur = increased severity |
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Definition
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Term
pulsus parvus et tardus (weak, delayed pulse) narrow pulse pressure |
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Definition
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Term
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Definition
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Term
paradoxically split S2 (if severe) S4 if LVH |
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Definition
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Term
Treatment of aortic stenosis |
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Definition
aortic valve replacement (AVR) once sxatic
severe AS is preload dependent --> avoid exertion, venodilators, & negative inotropes (CCB, BB) |
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Term
obstruction of flow from LA to LV --> LAE & increased LA pressure --> pulm HTN |
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Definition
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Term
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Definition
rheumatic heart disease (RHD)
MC cause by far |
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Term
Clinical manifestations of mitral stenosis |
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Definition
- R-sided heart failure
- pulmonary HTN - hemoptysis
- ATRIAL FIBRILLATION
- mitral facies (flushed cheeks)
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Term
diastolic rumble @ apex (low) in LLD - may be preceded by opening snap shorter A2-OS duration = increased severity |
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Definition
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Term
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Definition
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Term
Prominent S1 (closing snap) +- diminish w/ increased severity
OPENING SNAP (OS) |
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Definition
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Term
treatment of mitral stenosis |
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Definition
valvotomy in young pts
if rheumatic dx, sxatic, & valve orficie < 1.0 cm
repair preferred over replacement |
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Term
back flow from aorta to LV --> LV volume overload |
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Definition
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Term
Causes of aortic regurgitation |
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Definition
rheumatic dz, HTN
endocarditis, Marfan
Syphilis
Anklyosing Spondylitis |
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Term
Clinical presentation of aortic regurgitation |
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Definition
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Term
diastolic decrescendo blowing @ LUSB - increases w/ handgrip, decreases w/ amyl nitrate +- Austin Flint Murmur: mid-late diastolic rumble @ apex |
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Definition
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Term
Bounding pulses (increased SV) WIDE pulse pressure |
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Definition
aortic regurgitation
pulse bisferiens (if combined AS+ AR) |
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Term
PE findings of aortic regurgitation |
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Definition
Hill- popliteal mmHg > brachial pressure
Demussets- head bobbing
Quincke pulses - nailbed pulsations
water hammer pulse
pistol shot over fem art. |
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Term
Treatment of aortic regurgitation |
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Definition
Meds: vasodilators (decreased afterload increases forward flow)
Sx: acute or sxatic AR or decreased LV <55% (need hyperdynamic ventricle to maintain CO) |
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Term
back flow from LV into LA --> LV volume overload --> decrease CO |
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Definition
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Term
Causes of mitral regurgitation |
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Definition
MVP is MCC
RHD, endocarditis
ischemia (ruptured papillary muscle/chordae s/p MI) |
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Term
Clinical manifestations of mitral regurg |
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Definition
Acute: pulm edema, dyspnea
Chronic: A fib, CHF. Maybe pulm HTN (not as often as MS) |
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Term
blowing holosystolic murmur @ apex increases with handgrip, LLD decreases with amyl nitrate |
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Definition
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Term
may have a brisk upstroke d/t hyper dynamic ventricle from increased preload & decreased after load |
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Definition
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Term
widely split S2 +- S3, decreased S1 |
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Definition
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Term
Treatment of mitral regurgitation |
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Definition
Meds: vasodilators-decrease afterload increases forward flow (ACEI)
SX: valve repair preferred vs valve replacement (acute/sxatic or LV < 55%) |
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Term
myomatous degeneration of mitral valve (floppy, redundant valve) |
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Definition
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Term
causes of mitral valve prolapse |
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Definition
MC in young women
connective tissue dz (Marfan, Ehlers Danlos) |
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Term
Clinical manifestations of mitral valve prolapse |
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Definition
Most asymptomatic
1. autonomic dysfunction: CP, panic attacks; arrhythmia --> fatigue
2. sx assoc w/ MR progression: fatigue, dyspnea, PND, CHF
3. stroke, endocarditic, PVC's |
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Term
Midsystolic ejection click @ apex decreased venous return (valsalve, standing, inspiration) --> earlier click & longer murmur |
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Definition
mitral valve prolapse
+- mid-late systolic murmur (MR) |
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Term
Narrow AP diameter Low body weight (thin) hypotension scoliosis, pectus excavatum |
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Definition
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Term
Treatment for mitral valve prolapse |
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Definition
reassurance good prognsis in asymptomatic pts or mild sx
BB for autonomic dysfunction |
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Term
R ventricular outflow obstruction of blood across the pulmonic valve |
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Definition
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Term
almost always congenital & a disease of the young (ex congenital rubella syndrome) |
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Definition
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Term
harsh mid systolic ejection crest-decrescendo murmur (maximal @ LUSB) radiates to neck murmur increases w/ inspiration signs of R -sided HF. Systolic ejection click |
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Definition
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Term
tx of choice for pulmonic stenosis |
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Definition
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Term
MCC of pulmonic regurgitation |
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Definition
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Term
Graham Steell murmur: brief, decrescendo early diastolic murmur @ LUSB with full inspiration |
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Definition
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Term
mid-diastolic rumble @ LLSB (xyphoid border) opening snap |
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Definition
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Term
holosystolic murmur high pitched @ subxyphoid area (L mid sternal border) Carvallo's sign: increased murmur intensity w/ inspiration |
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Definition
tricuspid regurgitaiton
Carvallo's sign helps to distingush TR from MR |
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