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PANCE - CARDIO
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76
Science
Graduate
09/27/2015

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Cards

Term
Classic regimen for coronary artery disease/angina pectoris
Definition

daily ASA

sublingual NTG prn for pain

daily BB

statin (if increased LDL)

Term
DOC for acute management of acute symptoms of angina
Definition
NTG
Term
CI for nitro
Definition

SBP < 90

right ventricular infarction

use of viagra (sildenafil) & other PDE-5 inhibitors

Term
1st line drug for chronic treatment or coronary artery disease
Definition
BB
Term
MCC of coronary artery disease
Definition
angina pectoris
Term
substernal chest pain often brought on by exertion (d/t decreased supply & increased demand)
Definition
angina pectoris
Term
what is the most useful noninvasive screening tool for CAD/angina pectoris?
Definition
stress test
Term
what is the definitive diagnosis tool for CAD/angina pectoris?
Definition
coronary angiography
Term
Initial stress test of choice for most patients w/ normal resting ECG
Definition

treadmill test 

DOESNT assess region of ischemia

Term
MC used to test puts w/ baseline ECG abnormalities
Definition

radionuclide myocardial perfusion imaging (MPI)

DOES identify regions of ischemia

Adenosine or Dipyridamole (Persantine)

Term
CI to radionuclide myocardial perfusion imaging (MPI)
Definition
asthmatics (causes bronchospasm)
Term
Stress testing done in patients unable to exercise
Definition

Pharmacologic stress testing

Adenosine or dipyridmaole 

vasodilators preferred with MPI

caution: avoid vasoconstrictors 24h prior

Term
Stres echocardiography
Definition

usues dobutamin

used in pts w CI to vasodilators or w/ recent vasoconstrictor use

 

Term
Revascularization techniques for management of angina
Definition

1. PTCA (percutaneous transluminal coronary angioplasty)/ PCI (Perc coronary intervention)

2. CABG (coronary artery bypass graft)

Term
PTCA or PCI indications
Definition

1 or 3 vessel dz NOT involving main left coronary artery + normal or near normal left ventircular function

combo of ASA + clopidogrel (Plavix) used after

Term
CABG indications
Definition
left main coronary artery disease, symptomatic 3 vessel dz, left ventricular ejection fraction < 40%
Term
Diastolic murmurs
Definition

ARMS rest

Aortic regurg, Mitral stenosis

Term
Location of intensity
Definition

Apple Pies Taste Mmmmm

Aortic : R 2nd ICS 

P : L 2nd ICS

Tricuspd: L 4th ICS (erbs @ 3 ICS)

Mitral : 5th ICS (mid clavicular line) apex

Term
radiation of aortic stenosis
Definition
carotid
Term
radiation of mitral stenosis
Definition
none
Term
radiation of aortic regurg
Definition
L upper sternal border
Term
radiation of mitral regurg
Definition
axilla
Term
_____ murmurs are intensified when patient sits up and leans forward
Definition
aortic (AS, AR)
Term
_____ murmurs are intensified when patient lays on left side (decubitus position)
Definition

mitral 

(MR, MS)

Term
Increased venous return INCREASES _____
Definition

ALL MURMURS/ opening snap

ie squatting, leg raise, laying down

****exceptions: decreased murmur of HCM & delayed ejection click (decreased prolapse/shorter murmur duration) of MVP

Term
Inspiration increases venous return on the right side---?
Definition

increases ALL murmurs/opening snap on the R side (decreased ejection click R side)

right sided murmurs heard best w/ inspiration

Term
expiration increases venous return on left side
Definition

increase all murmurs/opening snap on the L side 

(delayed ejection click on the L side)

left sided murmurs best heart after maximal expiration

Term
Handgrip increases after load (by compressing arteries of UE) leading to decreased LV emptying (decreased forward flow & increased backward flow)
Definition

AR, MR, increases with hangrip d/t backward flow

MS increases d/t to afterload

Term
amyl nitrate decreases afterload (direct arteriolar vasodilator) leading to increased LV emptying (increases forward flow & decreases backward flow of blood
Definition

AR, MR decreases with amyl nitrate

(this is why afterload reducers like ACEI are used in tx)

Term
CXR classic triad : egg on a string appearance of heart, increased pulmonary vascular congestion, mild cardiomegaly
Definition
transposition of the great vessels
Term
MC type of CHD
Definition
ventricular septal defect
Term
Harsh holosystolic murmur @ L sternal border, LVH + RBH (biventricular hypertroph)
Definition
VSD
Term
treatment of VSD
Definition

35% close spontaneously

sx

diuretic 

digoxin early

Term
Aortic Stenosis
Definition

LV outflow obstruction --> fixed CO

increased afterload --> LVH

Term
causes of aortic stenosis
Definition

degeneration >70

congenital <70

rheumatic fever

Term
clinical manifestations of aortic stenosis
Definition

angina 

syncope

CHF

Term
systolic "ejection" crescendo-decrescendo @ RUSB
later peaking murmur = increased severity
Definition
aortic stenosis
Term
pulsus parvus et tardus (weak, delayed pulse)
narrow pulse pressure
Definition
aortic stenosis
Term
PE: LV heave d/t LVH
Definition
aortic stenosis
Term
paradoxically split S2 (if severe)
S4 if LVH
Definition
aortic stenosis
Term
Treatment of aortic stenosis
Definition

aortic valve replacement (AVR) once sxatic

 

severe AS is preload dependent --> avoid exertion, venodilators, & negative inotropes (CCB, BB)

Term
obstruction of flow from LA to LV --> LAE & increased LA pressure --> pulm HTN
Definition
mitral stenosis
Term
Cause of mitral stenosis
Definition

rheumatic heart disease (RHD)

MC cause by far

Term
Clinical manifestations of mitral stenosis
Definition
  • R-sided heart failure
  • pulmonary HTN - hemoptysis
  • ATRIAL FIBRILLATION
  • mitral facies (flushed cheeks)
Term
diastolic rumble @ apex (low) in LLD - may be preceded by opening snap
shorter A2-OS duration = increased severity
Definition
mitral stenosis
Term
PE: LAE
Definition
mitral stenosis
Term
Prominent S1 (closing snap) +- diminish w/ increased severity

OPENING SNAP (OS)
Definition
mitral stenosis
Term
treatment of mitral stenosis
Definition

valvotomy in young pts

 

if rheumatic dx, sxatic, & valve orficie < 1.0 cm

 

repair preferred over replacement 

Term
back flow from aorta to LV --> LV volume overload
Definition
aortic regurgitation
Term
Causes of aortic regurgitation
Definition

rheumatic dz, HTN

endocarditis, Marfan

Syphilis

Anklyosing Spondylitis

Term
Clinical presentation of aortic regurgitation
Definition
L-sided heart failure
Term
diastolic decrescendo blowing @ LUSB - increases w/ handgrip, decreases w/ amyl nitrate
+- Austin Flint Murmur: mid-late diastolic rumble @ apex
Definition
aortic regurgitation
Term
Bounding pulses (increased SV)
WIDE pulse pressure
Definition

aortic regurgitation

 

pulse bisferiens (if combined AS+ AR)

Term
PE findings of aortic regurgitation
Definition

Hill- popliteal mmHg > brachial pressure

Demussets- head bobbing 

Quincke pulses - nailbed pulsations

water hammer pulse

pistol shot over fem art.

Term
Treatment of aortic regurgitation
Definition

Meds: vasodilators (decreased afterload increases forward flow)

 

Sx: acute or sxatic AR or decreased LV <55% (need hyperdynamic ventricle to maintain CO)

Term
back flow from LV into LA --> LV volume overload --> decrease CO
Definition
mitral regurgitation
Term
Causes of mitral regurgitation
Definition

MVP is MCC

RHD, endocarditis

ischemia (ruptured papillary muscle/chordae s/p MI)

Term
Clinical manifestations of mitral regurg
Definition

Acute: pulm edema, dyspnea

Chronic: A fib, CHF. Maybe pulm HTN (not as often as MS)

Term
blowing holosystolic murmur @ apex
increases with handgrip, LLD
decreases with amyl nitrate
Definition
mitral regurgitation
Term
may have a brisk upstroke d/t hyper dynamic ventricle from increased preload & decreased after load
Definition
mitral regurgitation
Term
widely split S2
+- S3, decreased S1
Definition
mitral regurgitation
Term
Treatment of mitral regurgitation
Definition

Meds: vasodilators-decrease afterload increases forward flow (ACEI)

 

SX: valve repair preferred vs valve replacement (acute/sxatic or LV < 55%)

Term
myomatous degeneration of mitral valve (floppy, redundant valve)
Definition
mitral valve prolapse
Term
causes of mitral valve prolapse
Definition

MC in young women

 

connective tissue dz (Marfan, Ehlers Danlos)

Term
Clinical manifestations of mitral valve prolapse
Definition

Most asymptomatic

1. autonomic dysfunction: CP, panic attacks; arrhythmia --> fatigue

 

2. sx assoc w/ MR progression: fatigue, dyspnea, PND, CHF

 

3. stroke, endocarditic, PVC's

Term
Midsystolic ejection click @ apex
decreased venous return (valsalve, standing, inspiration) --> earlier click & longer murmur
Definition

mitral valve prolapse

 

+- mid-late systolic murmur (MR)

Term
Narrow AP diameter
Low body weight (thin)
hypotension
scoliosis, pectus excavatum
Definition
mitral valve prolapse
Term
Treatment for mitral valve prolapse
Definition

reassurance good prognsis in asymptomatic pts or mild sx

BB for autonomic dysfunction

Term
R ventricular outflow obstruction of blood across the pulmonic valve
Definition
pulmonic stenosis
Term
almost always congenital & a disease of the young (ex congenital rubella syndrome)
Definition
pulmonic stenosis
Term
harsh mid systolic ejection crest-decrescendo murmur (maximal @ LUSB) radiates to neck
murmur increases w/ inspiration
signs of R -sided HF. Systolic ejection click
Definition
pulmonic stenosis
Term
tx of choice for pulmonic stenosis
Definition
balloon valvuloplasty
Term
MCC of pulmonic regurgitation
Definition
pulmonary HTN
Term
Graham Steell murmur: brief, decrescendo early diastolic murmur @ LUSB with full inspiration
Definition
pulmonic regurgitation
Term
mid-diastolic rumble @ LLSB (xyphoid border)
opening snap
Definition
tricuspid stenosis
Term
holosystolic murmur high pitched @ subxyphoid area (L mid sternal border)
Carvallo's sign: increased murmur intensity w/ inspiration
Definition

tricuspid regurgitaiton

Carvallo's sign helps to distingush TR from MR

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