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Palmer Microbiology Unit 4
Final unit over bacteria
62
Microbiology
Graduate
02/14/2011

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Term
cornebacterium diphtheriae
Definition
Babes-Ernst bodies
Diptheria toxin: shuts off protein synthesis in epithelial cells.
Diptheria means leathery
Treatment: anti toxin
Term
A. Nocardia
Definition
Aerobic
Leads to lumpy jaw
Term
Farmer's Lung
Definition
Caused by Thermophilic Actinomycytes
"Allergic pneumonitis"
Term
Whipple's disease
Definition
Caused by Thermophilic Actinomycetes: Thrpheryma whipplii
Malabsorption disease
Term
Tuberculosis
Definition
"Consumption"
Caused by Mycobacterium tuburculosis
M. bovis can infect humans~milk pasteurization
Term
Pott's disease
Definition
TB infection of vertebral column
Term
Granuloma
Definition
Gathering of activated macrophages around TB
Term
Ghon's focus
Definition
primary lestion of TB
Term
Myobacterium leprae
Definition
Causes leprosy AKA Hansen's disease
Armadillo is a non human source
Lion Face and hypethesia (numbness)
Term
Clostridium
Definition
Oxygen triggers sporulation
Produce toxins
Term
Clostridium perfringens
Definition
Entrerotoxin killed in cooking, produced in gut
Causes Gas gangrene, Cellulitis, and clostroidial food poisoning
Term
Gas gangrene
Definition
caused by C. perfringens
Fermentation of muscle tisue, death in 2 days
Term
Cellulitis
Definition
Caused by C. perfringens
Term
Clostridial food poisoning
Definition
Caused by C. perfringens
Third most common cause of food poisoning in US
No fever, no nausea, no vomiting, yes cramps and diarhea.
Term
Clostridium difficile
Definition
Normal GI flora
highly resistant to antibiotics
Treatment, fecal transfer
Term
Clostridium botulinum
Definition
Most potent biological toxin-potential weapon
Blocks neurotransmission-Flacid Paralysis
Toxin is heat liable
Term
Infant botulism
Definition
in vivo production of botulism toxin in innfant's large bowel.
floppy baby
Spores found in honey
Term
Clostridium tetani
Definition
Resembles tennis racket
Causes tetanus and Spastic paralisis
Sardonic smile
Term
All gram negative bacteria have...
Definition
endotoxins
Term
Neisseria spp.
Definition
Look like coffee beans
Term
Neisseria gonorrheoeae
Definition
2nd most common STD in US
Has Pilli
Porin protein interferes with neutrophil killing.
Women more likely to be infected after exposure.
Term
Purulent conjunctivitis
Definition
associated with Neisseria gonorrhea
Term
Neisseria meningitidis
Definition
Releases blebs of LOS
Abrupt onset of conditions
Kernig's and Brudzinski's orthopedic tests will be positive
25% mortality with treatment
Term
Escherichia Coli
Definition
Normal flora in GI tract
A UTI can cause back pain
Majority of UTI's are caused by E. Coli, can lead to septicemia.
Term
Enterotoxigenic E. Coli
Definition
Traveler's and infant diarrhea
Term
Enterohemorrhagic E. Coli
Definition
Shiga toxin
Bloody diarrgea
Death
Term
Salmonella
Definition
Not a toxin, a bacterial infection
Chickens and turtles (all animals)
Term
Enteric Fever
Definition
Caused by Salmonella typhi
Intestinal hemorrhage
Term
Shigella spp
Definition
inculdes S. dysenteriae
Watery diarrhea
Blood in stool
Term
Yersinia spp
Definition
The plague, black death
Transmited by the rat flea
3 forms
Septicemic, pneumonic, bubonic
Term
Bubonic plague
Definition
Not contagious, spreads through vector.
Term
Klebsiella pneumoniae
Definition
Capsule
Gooey mucoid
Aspired
Alchoholics prone
Also causes wound and uti's
Term
Proteus spp
Definition
Second major cause of UTI's
eliminates urease
Term
Serratia marcescens
Definition
Produce red pigment
Grows on soup, but not a mold
Term
Vibrio spp
Definition
found in shell fish, water, estuaries
Causes Cholera
Term
Vibreo cholerae
Definition
"rice water" stools, extreme diarrhea
Replace water and electrolites!
Term
Campylobacter jejuni
Definition
Found in raw chicken
diarrhea, malaise, bloody stools
Guillaine-Barre syndrome (paralysis)
Term
Helicobacter pylori
Definition
In 2/3 of everyone's stomachs
Can cause ulcers
Term
Pseudomonas
Definition
Produce water soluble blue green pigments
Smells like musty grapes
Resistant to antibiotics
can grow in distilled water and disinfectant.
Causes death by making biofilm in patients with cystic fibrosis or severe burns
Swimmer's ear and hot tub folliculitis
Term
Haemophilus influenza
Definition
Can cause meningitis
Capsule makes type B important
Big cause of Otitis media
Term
Heamophilus ducreyi
Definition
STD
chancroid or soft chancre: painful, bleeds easily, soft raised border
Term
Bordetella pertussis
Definition
causes pertussis (whooping cough)
vaccine destroys toxin, not bacteria
endemic worldwide
Term
Brucella spp
Definition
Contracted from contaminated milk
Causes undulant fever
Term
Legionelle pneumophila
Definition
First described in 1976 after a pneumonia outbreak at the American Legionnaire's convention
Faculative intracellular paracytes
can live within macrophages and amoeba
Term
Bartonella spp
Definition
cat scratch disease
Term
Treponema pallidum pallidum
Definition
causes syphilis
cuses canchre
open rash
"great pox"
Term
T pallidum pertenue
Definition
Yaws or frambesia (red rasberry lesions)
Term
Leptospira interrogans
Definition
Hook at one end
Shed in animal urine
Term
Leptospirosis
Definition
Urinary tract disease
Weil's disease
Term
Borrelia recurrentis
Definition
Ticks and lice spread
up to 10 relapses occur
Term
Borrelia burgdorferi
Definition
Lyme disease:
Migrains
Bullseye lesion
Bell's Palsy
Term
Mycoplasma
Definition
No cell wall
Worm like
smallest free licing bacterium
Term
Mycoplasma pneumoniae
Definition
walking pneumonia
antibiotics targeting cell wall ineffective
Term
Rickettsia spp
Definition
Rocky mountain spotted fever
spread by arthropods (ticks, mites, lice, fleas)
Term
Rickettsia prowazekii
Definition
Causes Epidemic Typhus and Brill zinsser disease (relaxing fever)
Vector: human body louse
Term
Rickettsia typhi
Definition
Causes endemic AKA Mexican typhus
Term
Orientia tsutsugamushi
Definition
causes scrub typhus
Vector: chigger form of mite
Asia and South Pacific
Term
Coxiella burnetti
Definition
Transmitted to cows by ticks, released into milk
Causes Q fever
Term
Chlamydiae spp
Definition
obligate intracellular
Energy paracytes
Term
Chlamydia trachomatis
Definition
Causes keratoconjunctivitis, leading cause of preventable blindness
Causes swimming pool conjunctivitis, neonatal conjunctivitis, and infant pneumonia
Term
Chlamydia...the STD
Definition
most common STD in US
Asymptomatic in women
May result in Reiter's syndrome
Term
Chlamydophila psittaci
Definition
Causes psittacosis, parrot fever, ornithosis
From birds
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