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common symptoms of End-Stage |
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Definition
fatigue, anorexia-cachexia, constipations, N/V, delirium, dyspnea, pain |
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SSRIs, other antidepressants |
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antihistamines, B blockers, statins, benzos |
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benzos, anti-hypertensives |
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a separate medical benefit |
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patient must have less than 6 months to live |
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pay little/ nothing for med (which are directly provided), med orders based on protocol, allows rapid change in pain meds if needed |
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hospice covers comfort care |
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Definition
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Definition
patients may have terminal illness, focused on comfort care, BUT may have condition with which they could live for years |
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severe COPD, painful conditions like compression fractures or rheumatoid arthritis |
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Definition
conditions where patients might live for years, but patient might need end of life care |
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palliative care is not necessarily terminal |
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Definition
could still have curative focus even while providing comfort |
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possible symptom management suggestions |
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Definition
appropriate meds, dosing and easiest route for patient |
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Definition
may be related to difficulty swallowing at end of life, potentially from severe nausea |
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Definition
cannot be used if patient is opioid NAIVE |
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appropriate initiation of fentanyl patch |
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Definition
patient must be taking at least 60 mg of morphine per day or equivalent for 25 mcg/hr patch |
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fentanyl patch can still cause nausea |
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Definition
because nausea caused by opioid is a systemic effect |
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fentanyl patch may be ineffective in cachectic patients |
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Definition
because in these patients there is LESS fat leading to less absorption |
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Definition
potential issue in cancer patients |
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Term
concentrated opioid solutions |
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Definition
small volume, easier to mix with food |
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concentrated opioid solutions |
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Definition
can be placed under tongue and allow to be absorbed if patient is not eating at all |
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concerns when using concentrated opioid solutions |
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Definition
MUST be careful with dosing, use dropper that comes with bottle, educate caregiver! |
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Definition
as needed/ short term basis due to dosing limitations and not easy route |
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at home with ACUTE need may "make" suppositories |
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Definition
butter/ vaseline can be used with smaller oral tablets of oxycontin/ MS contin (ONLY do this other options are not available) |
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Definition
allow the most flexible dosing (easy adjustment) |
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SC route preferred over IV rout |
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Definition
when at home because there is lower risk of infection |
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Definition
volume limitations when doses are increased |
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epidural or intrathecal route |
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Definition
useful if other methods not effective, more complicated procedure |
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allow drug delivery to most localized area (trathecal/ epidural) |
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Definition
may provide better pain relief, reduces CNS side effects |
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Definition
patient can take more medication |
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Definition
physical symptoms if the med is not taken |
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Definition
taking drug becomes more important that the original benefit from it |
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an addict takes a med to get away from life |
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Definition
someone seeking pain relief takes med to get on with life |
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Definition
does not facilitate the healing of wounds or prevent pressure ulcers in end of life |
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increased risk of aspiration, diarrhea and other complications |
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Definition
contribute to wasting syndromes |
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weight loss is common in end of life |
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Definition
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Definition
less appealing, body is slowing down |
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altered phisiology and body chemistry at end of life |
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Definition
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eliminate dietary restrictions |
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Definition
and provide favorite foods, smaller and more frequent |
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some potentially inappropriate meds for geriatrics |
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Definition
may become appropriate (anti-nausea); more worried about comfort than side effects |
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sometimes used for severe nausea because it is a very strong dopamine blocker |
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may be the cause of nausea especially as pain meds are increased |
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promethazine, prochlorperazine |
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Definition
may make constipation worse especially if it is the cause of nausea |
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Definition
may not need to treat hallucinations or behaviors; only an issue if at risk of harming self/ others |
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no need to start dementia meds |
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Definition
unnecessary offending medications |
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Definition
NMDA receptor antagonist properties, useful for allodynia |
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Definition
pain due to a stimulus that doesn't normally cause pain |
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appropriate for patients with allodynia |
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Definition
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Definition
must be dosed cautiously, not first line but might be useful for some cases |
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Definition
may also be helpful for allodynia |
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Definition
used in anethesia most commonly, also blocks NMDA; might be used for advanced allodynia cases |
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inflammation can be cause of pain in bone metastases |
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Definition
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dexamethasone, prednisone |
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Definition
useful for pain caused by inflammation (bone metastases) |
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Definition
might be useful for bone pain (high dose) |
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Definition
less effective than glucocorticoids, consider possible adverse reactions |
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subjective symptom of not being able to breath |
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Definition
not necessarily associated with decreased O2 in bloodstream, may occur with progressive cancer and other conditions |
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treatments of "air hunger" |
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Definition
oxygen, opioids, benzos are most common |
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Term
in terminal dyspnea, respiratory center |
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Definition
is like a thermostat that keeps heat pumping out when temp is already too hot |
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may calm respiratory center down |
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with hyperactivity of respiratory center you have |
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Definition
DECREASED risk of respiratory suppression, as long as doses are appropriate |
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Definition
easiest for opioids/ benzos for respiratory hyperactivity |
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not always effective in trials but often works in practice |
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benefits of nebulized opioids |
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Definition
may be related to Mu receptors in lungs |
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Definition
may be caused by nebulized opioid |
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best option for nebulized opioid |
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Definition
preservative-free intravenous opioid often used to prevent sensitivity |
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Definition
lroazepam oral, can be sublingual (can give IV via neb) |
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Definition
more predictable half-life |
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opioids and benzos can be used together |
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Definition
if added benefit seems to be helpful |
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suction for oral secretions |
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Definition
extremely uncomfortable and rarely necessary at end of life |
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if oral secretions are uncomfortable for the patient |
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Definition
anticholinergics can help |
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Definition
often preferred because a low dose can be used for unwanted oral secretions |
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Definition
stimulant that might be helpful for drowsiness/fatigue from opioids or other treatments |
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