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PaleoPath Final
Final Exam
224
Anthropology
Undergraduate 4
05/04/2011

Additional Anthropology Flashcards

 


 

Cards

Term
Inlays
Definition
is/are the second most common form of dental modifications
Term
super-maxillary/ Lion
Definition
Leontiasis Ossea involves hypertosis of cortical bone of the fact and cranium, most notably in the _______ region, which causes the face to have a ______ - like appearance
Term
China
Definition
The area with the highest rates of Leprmatious-type leprosy
Term
Osteoblasts
Definition
Osteosarcom usually starts in the _______-
Term
Men, women
Definition
Ankylosing spondylitis is more common in _________ than _________
Term
Congenital
Definition
Achodroplasia is a _________ genetic disorder
Term
Brittle Bone Disease
Definition
Another name for Osteogenesis Imperfecta
Term
Amputation
Definition
What was the most common historical treatment for Osteomyelitis
Term

Relieve cranial pressure and

swelling from cranial injury

Definition
What was the most common reason for performing trepanation preocedures
Term

Osteomyelitis derives from the roots osteo = bones

myelo = _______ and itis = ________

Definition
Marrow, inflammation
Term
Ankylosing spondylisits
Definition
Type of chronic, inflammatory arthritis of the spine
Term
Ablation
Definition
Purposeful extraction of the teeth
Term
Most individuals are asymptomatic
Definition
Why is the prevalence of Klippel-feil syndrome unknown?
Term
FOP
Definition
Malformation of the big toe is a classic sign of _______
Term
Osteoblatic activity
Definition
Often seen in individuals post-trepanations and indicates healing
Term
Metastasis
Definition
Term for when cancer cells travel to other parts of the body, grow, and replace normal tissue
Term
Mycobacterium tuberculosis
Definition
The bacterial cause of tuberculosis
Term
Texas, Lousianna, Hawaii
Definition
Small endemic foci of leprosy exist where?
Term
Large cranial vaults with small skull bases
Definition
Achondroplasia
Term
Juvenile fibromatosis
Definition
A differential diagnosis category for FOP that results from the formations of nodules on the face, scalp, back , and neck
Term
50%
Definition
What is the percent chance of inhereting Osteogenesis imperfecta with a single parent who has the disease
Term
Civil war
Definition
The Army medical museum was established to collect pathological specimens from the ________
Term
Ankylosing spodilytis, juvenile arthritis
Definition
Two differential diagnoses for klippel-feil
Term
Greek word for stone child
Definition
Lithopedion
Term
Africa
Definition
Where is the lowest prevelance of Leontiasis Ossea
Term

Extensice heterotopic ossification

(ossification outside the skeleton)

Definition
A classic feature of FOP
Term
Malformation of the big toe
Definition
The primary classic feature of FOP that is the only evidence at birth
Term
clinical characteristics of FOP that arise during the first decade
Definition

Painful, inflammatory soft tissue swellings

Nodules

soft connective tissure transformed into bone

via endochondral ossification

Term
Cervical manifestations of FOP
Definition

Stiffness in neck

Large posterior elements

tall, narrow bodies,

fusion of facet joints between c2-c7

Term
Skeletal manifestations of FOP
Definition

Short, malformed thumbs

Clinodactyly

Big toes

 Short, broad femoral neck

Proximal medial tibial osterochondromas

Heterotopic ossification

Term
Differential Diagnosis of FOP
Definition

Juvenile Fibromatosis - nodules

Lymphedema - fluid retention

Soft tissue sarcomas - cancer

Term
Pulmonary system
Definition
What is the primary target of tuberculosis
Term
Pterygium (webbing of the skin from the sides of the neck to the shoulders)
Definition
Often seen in patients with Klippel-Feil syndrome
Term
Torticollis
Definition
Shortening of the sternocleidomastoid muscle that pulls the mastoid process toward the sternoclavicular joint of the same side of the neck (aka twisted neck) / seen in pts with Klippel-feil
Term
How do we know that Klippel-feil individuals can live long lives
Definition
noted in patients of seventy years old
Term
No
Definition
Are there hereditary influences to Klipper-feil
Term
Headaches
Vague nonradicular weakness and numbness
Definition
What are the mild complaints noted by pts with Klippel-feil
Term
Type I
Definition
Massive fusion of the cervical spine seen in Klippel-feil
Term
Type II
Definition
Fusion of the 1st or 2nd vertebra seen in Klippel-feil
Term
Type III
Definition
Presenceof thoracic or lumbar spine anamolies in association with Type I or Type II Klippel-feil
Term
Juvenile Rheumatiod Arthritis
Ankylosing spondylitis
Definition
Differential diagnoses of Klippel-Feil
Term
Coloring
Scrapping
Inlays
Extraction
Definition
What are the most common forms of dental modification
Term
Certain practices change the occlusion and biomechanics of the jaw
Definition
Culturally induced modifications are considered patholigies because ________
Term
Ablation
Definition
Extraction of healthy teeth generally associated with a rite of passage, a mourning ritual, or a visible recognition of pain tolerance
Term
Filing
Definition
Changing the shape of teeth for cosmetic purposes (commonly done with stone)/ Performed by the Moi of vietman
Term
Mayan and other mesoamerican cultures praciticed which form of dental modification
Definition
Inlays
Term
Task-wear versus Intentional Modification
Definition
Typically occurs on the non-occlusal surfaces
more common in female
More pronounced with age
More posterior teeth are affected
Involves surfaces other than labial
Assymetrical
Term
Intentional versus accidental
Definition
Ablation
Term
Abrasions
Definition
Most likely occuptional modifications
Term
Notching or grooves
Linear Enamel Hypoplasias
Flint-knapping
Definition
Differential diagnosis of cultural dental modification
Term
Other causes of differential diagnosis for intentional dental modifications
Definition
Toothpicks
clay-stemmed pipes
Labrets
Term
What is the purpose of dental modification
Definition
Influential individuals demostrating status and affiliation
Term
Cancer
Definition
The uncontrolled growth of abnormal cells in the body
Term
How do cancer cells differ from normal cells
Definition
They don't die
Term
Primary bone cancer
Definition
When cancer begins in the bone
Term
Greeks
Definition
Who were the first to identify cancer
Term
In the last 200 yrs
Definition
How recent were cancer developemnts and understandings
Term
What causes cancer
Definition
Genetics
Environment
Radiaion/ viruses/ chemicals and toxins/ anything that can damage DNA
Term
Osteosarcoma
Definition
Name one of the most common malignant neoplasms of bone
Term
40-60%
Definition
What percentage of primary malignant tumors that are osteosarcomas
Term
7%
Definition
What is the percentage of osteosarcomas in adults
Term
19%
Definition
What percentage of all bone tumors does Osteosarcoma represent
Term
Juveniles (<20)
Definition
Who are most likely to be affected by Osteosarcoma
Term
Males
Definition
What gender is more likely to be affected by Osteosarcomas
Term
Formation of Osteoids
Definition
What is the primary diagnosis indicator of osteosarcoma
Term
Sunburst
Codman's Triangle
Definition
What king of appearances can Osteosarcomas have that indicate a diagnosis
Term
Swelling over a bone
Pain
Pathologicals Fracture
Definition
What are other diagnoses of osteosarcomas
Term
What kind of survial rates can a person with Osteosarcomas expect
Definition
Depends on treatments plans (20% effective) with surgery only
Term
What is the 2nd leading cause of death in industrialized nations
Definition
Cancer
Term
Why might people considered cancer a new disease
Definition
Few references to cancer in antiquity (possible 176 specimens)
Term
Why would it be important to look for osteosarcomas in the archaeological record
Definition
Produces in bone and therefore more likely to survive in the record
Term
Osteogenesis Imperfecta
Definition
A genetic disease in which an individual has compromise collagen or less than a normal amount
Term
1 out of every 30,000
Definition
How common is Osteogensis Imperfecta
Term
75%
Definition
What is the percentage of inhereting OI if a person has 2 carriers parents
Term
25%
Definition
What is the percentage of OI for individuals with no familial background with the disease
Term
Type I OI
Definition
The mildest form of ______ where most fractures (20-40) occur before puberty/ poor muscle tone/ blue-purple- gray sclera/ minimal bone density/ possible hearing loss/ decrease post-puberty symptoms with increase post menopause and after age 60 in men
Term
Type II OI
Definition
is the most severe form/ frequently lethal shortly after birth/ nurmerous fractures and severe bone deformity
Term
What is the leading cause of death with Type II OI
Definition
Respiratory failure due to multiple rib fractures
Term
Name three Characteristics of OI
Definition
Insufficient amount of bone
Low cortical thickness and trabecular bone
Transverse fractures
Term
Fractures arising from minor or unrecognized force
Definition
A common characteristic of OI
Term
Rickets
Definition
A differential diagnosis of OI caused by Vit D deficiency
Term
Non-accidental injury
Definition
A common differential diagnosis of OI that results from child abuse
Term
Temporary brittle bone disease
Definition
A differential diagnosis of OI caused by scurvy or copper defieciency occuring during the first 12 months of life
Term
Two most common differentail diagnoses of Leontiasis Ossea
Definition
Paget' disease
Poly-ostotic (cranio -facial) fibrous displasia
Term
Leontiasis Ossea is occasionally a symptom of ________
Definition
Renal Osteodystrophy/ Hyperparathyroidism/ Agromegaly/ Cherubism
Term
Leprosy
Definition
Leontiasis Ossea could resemble which disease
Term
western Europe
Definition
Where is Leontiasis Ossea predominately found
Term
Asia
Definition
Name another area in which Leontiasis Ossea is rare
Term
Current controversy of Leontiasis Ossea
Definition
Is it a symptom of other diseases or can it stand as a disease alone
Term
Fibrous dysplasia
Definition
One common differential diagnosis of Leontiasis Ossea that is a rare nonheritable congenital skeletal development disorder in which the medulla bone is replace by fibrous tissue
Term
Paget's disease of the bone
Definition
A differential diagnosis of Leotiasis Ossea which is a chronic disorder that typically affects the metobolic rate between the resoprtion and production of bone material resulting in enlarged and deformed bones
Term
Hypertosis Frontalis Interna
Definition
A differential diagnosis of leontiasis Ossea characterized by the overgrowth of the inner table of the frontal bones
Term
Agromegaly
Definition
A differential diagnosis of Leontiasis Ossea that results when the pituitary gland produces excess growth after puberty
Term
Overgrowth of facial bones
Dramatic increase in skull weight
Cranial nerve compression
Exophthalmos/ Increased cranial pressure
Definition
Classic symptoms of Leontiasis Osseas
Term
May 21, 1862
Definition
The date that the Army medical museum was established
Term
Study the effects of gunshot wounds/ amputations/ and other surgical procedures
Definition
Purpose of the original Army medical museum
Term
19th and 20th century change the Army medical museum in which way
Definition
The Army medical museum became involved in medical research
Term
By WWII the Army Medical museum changed its primary focus to _______
Definition
Pathology
Term
AFIP
Definition
Armed Forces Institue of Pathology located on camp walter reed
Term
Lithopedion
Definition
Fetus that has become bony or calcified first described in the 10th century
Term
Accidentally during X-rays
Definition
How are most cases of Lithopedion Identified
Term
Yes
Definition
Can a women deliver a healthy child while still maintaining a lithopedion
Term
Craniosynostosis
Definition
Premature suture closure
Term
What are the three types of craniosynostosis
Definition
Isolated effect
One of multiple unrelated defects
part of a syndrome
Term
Sagitaal suture
Definition
What is the most common premature suture closure in cranionsynostosis (40-60%) of all cases
Term
What are the common syndromes that craniosyntostosis results in
Definition
Apert/ Saethre-chotzen/ Crouzon
Term
3.1-4.8 per 10,000
Definition
how common is craniosynostosis
Term
Is there an easy fix to craniosynostosis
Definition
No care is longitudinal
Term
What is the most common cause of short limb dwarfism
Definition
Achondroplasia
Term
Achondroplasia
Definition
What is the most common form of skeletal dysplasia
Term
How prevelent in Achondroplasia
Definition
1 in every 25,000-50,000 live births
Term
What gender is more affected by achondroplasia
Definition
males
Term
What are the average heights for individualts with achondroplasia
Definition
4'3" male/ 4'0" female
Term
mutation in Fibroblast growth factor gene 3
Definition
cause of achondroplasia
Term
True or false - Two parents without achondroplasia cannot have a child with it
Definition
False
Term
What is the percentage of inheretance of achondroplasia when the child only has one parent with the disorder
Definition
50%
Term
What is the percentage of inheretance of achondroplasia when the child has two parent's with the disorder
Definition
75%
Term
When can achondroplasia be diagnosed during pregnancy
Definition
3rd trimester
Term
Is the foramen magnum in achondroplasiacs narrow or wide
Definition
narrow
Term
Decreased muscle tone/ short stature/ Disproportionately large head to body size
Definition
General symptoms of achondroplasia
Term
How does achondroplasia affect the spine
Definition
Posterior vertebral scalloping/ kyphosis-lordosis/ widening intervertebral discs/ increased angle between sacrum and lumbar spine
Term
How does Achondroplasia affect the chest
Definition
anterior flaring of the ribs / anteroposterior narrowing of the ribs
Term
Small-squared iliac wings
Definition
A diagnostics feature of achondroplasia
Term
A diagnostic feature of achondroplasia
Definition
champagne glass type pelvic inlet
Term
How are the limbs affected in achondroplasia
Definition
Shortened femora and humeri/ trumpet shaped / thick appearance/ long fibula
Term
Trident
Definition
How are the hands shaped in individuals with achondroplasia
Term
Differential diagnoses of achondroplasia
Definition
achondrgenesis/ capomeliac dysplasia/ thanatophoris dysplasia primordial dwarfism/ pituitary dwarfism/ laron syndrome
Term
How much of Europe was affected by Leprosy during the crusades
Definition
1/4
Term
Who were the primary care-givers to individuals with leprosy
Definition
religious individuals
Term
Why are leprosy rates permantly lowered in Europe
Definition
Improved hygiene + large plague death toll
Term
How was Leprosy originally dealt with
Definition
Individuals with leprosy were isolated into special houses or colonies (lazar / leprosaria
Term
Where is leprosy primarily found today
Definition
tropic and subtropic zones
Term
where are the highest concetrations of leprosy
Definition
devoloping countries / endemic to africa/ asia/ the pacific basin/ and latin america
Term
Of Latin America where is leprosy not endemic
Definition
Chile
Term
Who has a greater likelyhood of having leprosy
Definition
Men
Term
Why are there more deformities associated with leprosy in women than men
Definition
delayed reaction in women allow for greater time for disease to affect body
Term
Is there a gender preference to tuberculoid leprosy
Definition
NO
Term
Tuberculoid leprosy
Definition
which form has shorter dormancy period and more soft tissue involvement
Term
What happens to lesions in tuberculoid leprosy
Definition
They become hairless and dry
Term
How can tuberculoid leprosy manifest
Definition
One large red patch with well-defined raised borders or large hypopigmented assymetrical spot
Term
can spontaneous resolution of leprosy occur with lepromatous leprosy
Definition
No
Term
True or False? Lepromatous leprosy has a short dormancy and more soft tissue involvement
Definition
False
Term
Plaques/ Macules/ Papules/ Nodules
Definition
All can form with lepromatious leprosy but not tuberculoid leprosy
Term
Name 3 early symptoms of lepramatous leprosy
Definition
nasal stuffiness/discharge and bleeding/ and swelling in legs or ankles
Term
Nasal aperture deformation results from
Definition
Lepramatous leprosy
Term
What happens to the nasal spine in lepramatous leprosy
Definition
It is destroyed
Term
Pitting and absorption of the palate is often seen in tuberculoid leprosy. true or false
Definition
False - lepramatous
Term
True or false? The alveolar process is not affected by lepramatous leprosy
Definition
False - absorption of the bone occurs
Term
Why is the prevalence of leprosy low
Definition
Most people have a natural immunity
Term
pyogenic osteomyelitis/ treponemal disease/ fungal infection
Definition
differential diagnoses of leprosy
Term
What is inflammation in osteomyelitis
Definition
A secondary symptom of already infected medullary cavity
Term
What are some of the causes of Osteomyelitis
Definition
Trauma
disease
Bacteria
Term
How ancient is osteomyelitis and how do we know
Definition
Dates back to the Greeks and was written about in the play Philoctetes
Term
psiloma
Definition
Another name for osteomyelitis resulting from the loss of soft tissue and exposure of the bone
Term
Why was osteomyelitis so common during the civil war
Definition
Frequent and rapidly occuring trauma
Term
Which part of the body is most frequently affected by osteomyelitis
Definition
The tibia
Term
What is the second most frequently affected part of the body
Definition
The femur
Term
What is the percentage of Osteomyelitis caused by exogenous factors
Definition
47%
Term
What is the percentage of Osteomyelitis caused by vasular insufficiency factors
Definition
34%
Term
What is the percentage of Osteomyelitis caused by hematogenous factors
Definition
19%
Term
Name three diseases that can lead to osteomyelitis
Definition
tuberculosis/ syphillis/ and leprosy
Term
Name the two most common forms of bacteria that cause osteomyelitis
Definition
Staph aureus/ Streptococcus
Term
What percent of cases of osteomyelitis arise of complications from diabetes
Definition
30%
Term
At what age does the occurence of osteomyelitis drastically increase
Definition
Greater that 40 yrs
Term
Non-specific pain is a symptom of ______
Definition
Osteomyelitis
Term
A symptom of osteomyelitis is _______
Definition
fever for an extended period of time
Term
Where are the primary places which osteomyelitis occurs
Definition
vertebra/ long bones/ pelvis
Term
True or false? gout is a common differential diagnosis of OI which is a type of inflammatory arthritis
Definition
False - it is a differential diagnosis of osteomyelitis
Term
Name the differential diagnosis of osteomyelitis that is a malignant tumor
Definition
Ewing's sarcoma
Term
True or false? Septic arthritis is a differential diagnosis of osteomyelitis that is caused by bacteria in the blood flow
Definition
True
Term
Trapanation
Definition
The creation of a hole in the head
Term
How were trepanations typically performed
Definition
Cutting a hole in the head via a sharp tool or slowly scraping away the bone to form a hole
Term
Trepanations are typically done far away from where
Definition
Substantial muscle tissue areas such as the nuchal crest
Term
True or False? The range of hole size in trepanation increased over time as did the rate of survival
Definition
False - the sized decreased in size over time and the rate of survival increased
Term
Which side of the skull were many trepanations performed
Definition
Left
Term
What is the significance of the most trepanation holes being located on the left side of the skull
Definition
It demostrates that many were performed to relieve cranial pressure due to trauma such as hits on the head from other assailants ( most people are right-handed and therefore hit another on the left side of the head)
Term
What is the significance of the most trepanation holes being located on males
Definition
During ancient history men were primarily involved in warfare and violence not women
Term
Other reasons for trepanation
Definition
help with epileptic seizures/ mastoiditis/ possible religious or cultural significance
Term
What can be seen in some cases around the site of trepanation that indicates short-term healing
Definition
Hyper vascularity
Term
True or False? Extensive remodeling and rounding of margins indicate short term healing in trepanation
Definition
False - indicates long term healing
Term
What is the primary differential diagnosis of trepanation
Definition
tuberculosis
Term
What is the average survival rate for an individual who has undergone trepanation
Definition
50%
Term
True or false ankylosing spondylitis is latin for stiff spine
Definition
False - greek
Term
Spine stiffness and often complete fusion of the verts
Definition
Ankylosing spondylitis
Term
What kind of disease in ankylosing spondylitis
Definition
autoimmune
Term
What does autoimmune disease mean
Definition
A disease in which ones immune system attacks one's own body cells
Term
Are the genetic predispositions to ankylosing spondylitis
Definition
Yes as accordance to HLA-B27 antigen
Term
Possible evidence found in historical context in _________
Definition
Dinosaurs, cave bears, saber-toothed tigers
Term
What is the differential diagnosis of Ankylosing spondylitis thought to be associated with Egyptian mummies
Definition
DISH
Term
Is there fully successful treatment for AS
Definition
No - mainly pain management via NSAIDs and physiotherapy to enhance and restore functional ability
Term
What ethnicity is at a greater risk for AS
Definition
Caucasians
Term
What is the ratio of men to women with AS
Definition
3:1
Term
Why do physicians believe that the incidence of AS in women is underdiagnosed
Definition
Women tend to have milder symptoms
Term
What age does AS usually affect
Definition
Mainly young adults
Term
Chronic AS is classified by ______
Definition
continuing a long time with frequent reoccurence
Term
Insidious AS results operates or proceeds in an ___________ or seemingly harmless way bu with grave effet
Definition
Inconspicious
Term
DISH
Definition
Diffused idiopathic skeletal hyperstosis
- a differential diagnosis of AS in which there are no intervertebral discs and 2 out of every 3 cases are male/ described by a candle wax appearance
Term
Rheumatiod arthritis is a differential diagnosis of FOP that affects the synovial joints and connective tissue. True or False?
Definition
False - differential diagnosis of AS
Term
TB can be transmitted via
Definition

 

Inhaling fine droplets (aerosols) coughed out by an

infected carrier

 

Accidental ingestion of a victim's mucous secretions

 

Bodily wastes

Term

 

 

Bacilli overwhelm the immune system

Break out of tubercules in alveoli and spread throug

bloodstream 

(occurs in individuals with weakend immune systems)

 

Definition
“Active” TB
Term

Stong immune systems

Initial infection controlled by immune system

Bacilli remain confined to tubercules for yrs

Definition
Latent TB
Term
What are the clinical presentations of TB
Definition
perpetual cough/ fever/ weight loss/ night sweats/ loss of appetite/ fatigue/ swollen glands/ chills/ pain
Term
M. tuberculosis
Definition
Most common mode of infection for human type TB
Term
M. bovis
Definition
Bovine TB which can also be transmitted to humans
Term
M. africanum
Definition
Another type of TB
Term
What was a leading cause of death during the 17th through early-mid 20th century
Definition
TB
Term
How many individuals does TB kill anually
Definition
2 million
Term
How much of the world is affected by TB
Definition
Approximately 1/3
Term
What is a primary concern of TB
Definition
The reemergence of multiple drug-resistant strains
Term
MDR-TB
Definition
A drug-resistant strain of TB
Term
What is the percentage of cases of skeletal involvement with TB
Definition
5%
Term
What does TB do?
Definition
Created tubercules / granulomas that caseat necrosis
Term
What is another affect of TB
Definition
Hematogenous dissemination
Term
What parts of the skeleton are most affected by TB
Definition
Spine/ Hip/ Knee
Term
What part of the spine is most affected in TB
Definition

The lower thoracic and upper lumbar region

2-4 adjacent verts

Anterior vert body

Term

Can lead to Pott's disease

Kyphsis, gibbus deformity

Definition
TB
Term
Osteomyelitis/ AS/ scoliosis/ osteoporosis/ blasomycosis are differential diagnoses of _________
Definition
TB
Term

True or False?

Skull involvement from TB is rare except for in young chhildren?

Definition
True
Term
True or False? In children the cranial base is most affected by TB?
Definition
False - the vault
Term
In children TB presents in _______, _________ lytic focus up to 2cm and diameter
Definition
multiple, round
Term
In adults TB skull involvement is typically _______ and _________
Definition
Large and solitary
Term
Skull involvement of TB differential diagnosis in children include ______ and _________
Definition
Landerhans cell histiocytosis and metastatic neuroblastoma
Term
True or false? In Leontiasis Ossea differential diagnosis of the skull lesions include osteomyelitis/ tertiary aquired syphilis/ neoplasms/ and trepanation
Definition
False - Differential diagnosis of TB
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