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Mechanical, thermal, chemical insults can stimulate the nociceptors Inflammatory mediators can increase the sensitivity of nociceptors |
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Alpha Delta Fibers (A-fibers) |
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small myelinated nerve cells that produce fast well localized sharp pain. wider diameter = faster transmission |
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-smaller than alpha delta -unmyelinated and produce slow poorly -localized pain (diffused) these are the burning, throbbing pain -dull/achy -persists for a longer period of time |
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-ascending -nerves that send signal from stimulus to the brain |
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-descending -Brain sends impulse to the body |
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-a chemical substance that is released at the end of a nerve fiber by the arrival of a nerve impulse and causes the transfer of the impulse to another nerve fiber -More than 30 substances -Ex: acetylcholine, serotonin, dopamine |
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-theory of pain asserts that non-painful input closes the gates to painful input, which prevents pain sensation from traveling to the central nervous system. -Closing gates: massage, distraction (music therapy) -no drugs |
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s the process by which nervous activity is regulated by way of controlling the physiological levels of several classes of neurotransmitters. |
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-neuromodulators -Prostaglandins, bradykinin (mainly due to tissue injury) -These substances sensitize nociceptors in the PNS or CNS leading to responsiveness |
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-neuromodulators -Endorphins Beta-endorphins Enkephalin Dynorphins Endomorphins |
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-last less than 3 months, pain directly related to soft tissue damage such as sprained ankle or paper cut -a fibers |
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-C fibers -pain that persists beyond the usual course of acute disease or reasonable time for injury to heal. (greater than 3 months) |
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-Can cause disintegration of relationships -Effects social and work life |
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Visceral pain is pain that results from the activation of nociceptors of the thoracic, pelvic, or abdominal viscera. -think organs |
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-Somatic pain is a type of nociceptive pain that is also referred to as skin pain, tissue pain, or muscle pain. -the nerves that detect somatic pain are located in the skin and deep tissues. |
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-mild pain -use massages or distractions |
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-moderate pain -NSAIDS can be used |
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-pain -quality -region -severity -time |
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