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pain
acute & chronic pain
83
Health Care
Graduate
12/13/2008

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Term
Somatic pain
Definition
activation of nociceptos in peripheral tissues. C & A fibers transmit pain sensation.
Described as well-licalized aching or gnawing pain. i.e. bone pain muscle pain, postoperative pain.
Term
Visceral pain
Definition
visceral structures are stretched, compressed, invaded or distended. Poorly localized. Described as squeezing, cramp, colicky.
Term
Referred pain
Definition
type of visceral pain also known as verceral somatic reflex. Vague pain often w/ N&V
Term
Neuropathic pain
Definition
direct injury to neural tissue from tumor inflitration, erosion, or from cancer therapies. Associated w/ sensory, motor, and autonomic deficits accompany the symptoms of burning, squeezing, and sharp pain. i.e. brachial and lumbar plexopathies and post thoracotomy pain syndrome.
Term
Central pain
Definition
Affect CNS, involving 2nd and 3rd order neurons typified by abnormal sensibility to both pain and temp. i.e. neoplastic lesions along the spinothalamic tract or cerebral cortex projections, postherpetic neuralgia, and phantom limb pain.
Term
Sympathetic pain
Definition
pain can occur after fractures, thrombosis, lymphedema, dysautonomia including burning, allodynic pain, w/ sudomotor and vasomotor changes, edema, and coldness of area. Sympathetic nervous system changes affecting the area
Term
Nociceptors activated by only one type of stimulus
Definition
high-threshold mechanoreceptors
Term
A-delta afferent nerve fibers
Definition
small, rapid, myelinated = sharp & prickling pain
Term
C-afferent nociceptive neurons
Definition
small, slowly, unmyelinated plymodal receptors activated by wide variety of high-intensity stimuli, mechanical, chemical, temperature
Term
hyperalgesia
Definition
exaggerated pain response usually b/c of imprinting
Term
Urine concentrating ability is_______in neonates. Urine Osmolality is ____-_____mEq/L
Definition
limited; 700-800mEq/L
Term
Neonates have decreased renal response to ______
Definition
ADH
Term
Reanl plasma flow and GFR are _____that of the adult values.
Definition
1/2
Term
Maturational differences make it very difficult for the infant to handle fluctuations in fluid and solute loads. Hemostatic mechanisms are fully developed after _______yr(s) of life.
Definition
First year of life
Term
The excretion of a fluid bolus is d/t the limited______
Definition
GFR
Term
Normal neonate losses ______% of its body weight in the first few days of life due to loss of______&_______
Definition
5-15%; isotonic salt and water
Term
Pematurity increases neonatal fluid requirements. Fluid requirement is bases on what three factors?
Definition
weight, U/O, and serum sodium
Term
On day one neonate fluid requirements are _______(high or low)?
Definition
low; increasing over the next few days
Term
Glucose levels must be maintained. What happens to the levels in the first few hours of life? What should it not go below?
Definition
decreases; should not go below 45mg/dL
Term
What is given to replace glucose levels and what is the bolus and continuous infusion doses?
Definition
D10W; bolus 2-4mL/kg; Continuous infusion 4-6mg/kg/min
Term
D/t fluid and salt losses during first few days of life, the neonate is prone to hyper or hypo natremia?
Definition
hyper; d/t fluid losses
Term
What type of fluids are preferred in the OR?
Definition
isotonic solutions
Term
Glucose containing solutions are not used in the OR because?
Definition
D5=free water
Term
When critically ill children arrive in the OR w/ hyperalimentation the infusion should be______?
Definition
continued on a separate line;
deduct volume from isotonic operative fluids.
Term
Age related norms for HR & BP see pf 18 of textbook.
Definition
Term
If you suspect hypovolemia, how much fluid bolus should be give?
Definition
10-20ml/kg
Term
A normal healthy child should not be transfused until the Hct. is____
Definition
20-25%; A child w/ sever pulmonary disease requires a higher Hct. than a healthy child.
Term
If significant blood loss is expected the use of what 3 things may be necessary?
Definition
foley, central line, and art line
Term
Most of the heat loss form the baby is lost by?
Definition
radiation and convection
Term
The child should be considered poikilothermic which means?
Definition
cold blooded; use radiant warmers, warm air mattress, heat moisture exchangers and fluid warmers, but avoid hyperthermia
Term
A microdrip IV set should be used on children less than___kg.
Definition
50kg. The volume in the fluid container should not exceed the child's estimated fluid deficit.
Term
What type of mask is designed to minimized dead space?
Definition
Rendell-Baker / Soucek; however the most commonly used mask have a soft inflatable cuff
Term
What type of airway is usually not used in children?
Definition
Nasopharyngeal
Term
After intubation w/ ETT assess for a leak at _______cmH2O
Definition
20-25cmH2O
Term
A cuffed tube is ______mm larger?
Definition
0.5mm
Term
In Mapleson circuits what prevents rebreathing?
Definition
high fresh gas flows venting exhaled gas thru the APL valve before next inspriation.
Term
The efficiency of mapleson circuit is measure by the fresh gas flow required to?
Definition
eliminate CO2 rebreathing
Term
Advantages to mapleson circuit is:
Definition
decreases resistance b/c no valves or soda lime restriction.
Term
Disadvantage to Mapleson circuits is:
Definition
the need for high flows to eliminate rebreathing; pollution of the OR environment; loss of patient heat and humidity.
Term
Make sure read Dorsch chapter 8
Definition
Term
Define low birth weigh, very low, and extremely low.
Definition
<2500; <1500; <1000grams
Term
In premies small airways predispose them to?
Definition
obstruction and difficulty w/ ventilation. ETT INCREASES WOB greater than the infant
Term
In premies loss of muscle control caused by anesthesia increase_____?
Definition
Work of breathing
Term
Premies are more prone to what kind of tracheal problems?
Definition
subglottic stenosis, tracheal stenosis, and tracheobronchomalacia
Term
The premie's immature lung predisposes them to hypoxia. Low lung voulmes and compliance leads to an increased____?
Definition
intrapulmonary shunt and V/Q mismatch
Term
PEEP is used during anesthesia to maintain?
Definition
lung volume and prevent hypoxia and V/Q mismatch
Term
Premies are suceptible to what kind of respiratory problems?
Definition
Oxygen toxicity, barotrauma, and development of BPD
Term
Premies have a _______ventilatory response to carbon dioxide and ______further blunts this response
Definition
decreased; hypoxia
Term
premies have a biphasic ventilatory response
Definition
Term
Fetal heart is less compliant, it has less contractile tissue and more fibrous tissue and more dependent on?
Definition
Calcium.
Term
Premie Cardiac output is dependent on?
Definition
HR; small absolute blood volume; little autoregulation prediposes the preemie to CV collapse
Term
Open patent ductus arteriosus predisposes the preemie to?
Definition
pumonary HTN and CHF; PDA = right to left shunt
Term
Preemies are less sensitive to ______ and are increased risk for CV______
Definition
catecholamines; and CV collapse
Term
Preemie often have cognitive impairment d/t brain injury most commonly in the?
Definition
perventricular white matter
Term
IVH occurs in what percentage of preemies?
Definition
1/3 or 33%; IVH grades 1-4, 4 being the worst.
Term
Retinopathy of prematurity occurs in _____% of low birth wt. infants. Thought to be caused by what?
Definition
50%; variations in arterial oxygen and eposure to bright lights, free oxygen radicals may be another cause.
Term
preemies are susceptible to hypthermia, the epidermis has less______, this causes an increase in evaporative heat loss and insensible fluid loss
Definition
keratin. In addition they have little fat and a large surface area to mass ratio...KEEP THEM WARM!!
Term
Preemies...Reduced kidney function, plasma creatinine levels are_____, at risk for?
Definition
higher; hyponatremia
Term
Preemies are at risk for hypo and hyperglycemia. Decreased _______and _______stores.
Definition
glycogen and fat stores
Term
Preemies may be insulin resistant and may require_________to maintain normoglycemic?
Definition
insulin; monitor glucose closely!
Term
Liver has reduced hepatic proteins, at risk for spontaineous liver__________
Definition
hemorrhage
Term
Tissue O2 delivery is maximized by maintaing a Hct between ____-_____%
Definition
44-48%
Term
Explain why N20 is not routinely used on preemies. Note that the MAC requirement is less than the term infant.
Definition
N20 d/t decreases O2= desat quickly; also distension of airfilled spaces (gut)
Term
Preemies immature liver yield higher 1/2 times for opioids and benzos
Definition
Term
Necrotizing Entercocolitis NEC, is a life threatening situation caused by?
Definition
intestinal mucosa ischemia
Term
Early signs of NEC= feeding intolerance, name 3 more.
Definition
lethargy, temperature instability, and increased WOB
Term
Later signs of NEC are:
Definition
hypotension; abdominal distension, apnea, coagulopathy, and multiorgan failure. NEC IS A SURGICAL EMERGENCY
Term
Preparation for NEC surgery: albumin, FFP, platelets, PRBC'S, Epinephrine, Dopamine, and calcium gluconate...what's the Ca gluconate for?
Definition
treat hypotension.
Term
NEC emergency Pre-op assessment should include:
Definition
current meds, IV access, Dextrose infusion rates, H&H, electrolytes, and BG level.
Term
What are the intubation considerations for NEC emergencies?
Definition
RSI or awake d/t full stomach
Term
NEC need vascular access. What else is needed to surgery?
Definition
2 large bore IV's (22 gauge), A-line, CVP, Foley, NG tube
Term
Anesthesia technique most commonly used for NEC:
Definition
high dose ketamine or opioids, Fentanyl 20-50mcg/kg, muscle relaxant, small or NO inhalational gas.
Term
Preemie treatment of hypotension, bolus of fluid ___-___ml/kg. Run Dopa at ___-____mcq/kg/min. What other two considerations?
Definition
10-20 ml/kg; 5-20-mcg/kg/min; give Ca++ if giving blood, think stress dose of glucocorticoids.
Term
During NEC replace blood loss with?
Definition
PRBC's. Give platelets to maintain count >100,000.
Term
During NEC replace fluids villigently; not uncommon for a preemie to receive______of fluid during the case?
Definition
100ml/kg
Term
Ligation of patent Ductus Arteriosus d/t failure of closure is common in preemies. The PDA incures a severe ____-_____ shunt
Definition
left to right. With overload or pulmonary HTN shuting may be right to left producing cyanosis
Term
PDA is ligated thru a left_____?
Definition
thoracotomy
Term
PDA ligation monitors: BP cuff on right upper arm. ETCO2, pulse ox digits of right arm and lower extremity. What does it mean if you lose signal in the lower extremity?
Definition
ligated the AO. If you lose both you ligated the PA and there will be no ETCO2.
Term
PCA anesthesia: Fentanyl 20-50mcg/kg (the whole case) Pacuronium 0.2mg/kg, albumin 10ml/kg before induction to avoide hypotension. The surgery is about _____long the patient should be extubated when?
Definition
20 mins; the next day
Term
Inguinal hernia repair; common in preemies, use GA or RA. May need to give _____to prevent post op apnea?
Definition
caffeine. 10mg/kg prior to extubation
Term
INGUINAL HERNIA REPAIR avoid which medication?
Definition
fentanly; use tylenol; surgeons use local for pain control. Need stimulus to breath...otherwise stays vented.
Term
Pertem infants with BPD will have compensated ______ ______ and elevatied ______
Definition
respiratory acidosis and elevated ETCO2
Term
Inguinal hernia repair. RA is common; cuadal blockagde with ______caine _____% with epi 1:200,000 ______ml/kg
Definition
bupivicain 0.375%; epi 0.75ml/kg; works for 1-2 hrs. Excellent for preemies w/ BPD.
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