Term
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Definition
- Oil secreting gland of the skin
- Secrete: sebum
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Term
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Definition
| Secretory cells that contribute part of their protoplasm to the material secreted |
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Term
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Definition
- Increased sebum production
- Abnormal follicular desquamation
- Proliferation of Propioibacterium acnes
- Inflammation
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Term
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Definition
- 10-17 females; 14-19 males
- May appear first at 25 years or older
- More severe in males than females
- Lower incidence in Asians and African Americans
- Exposure to acnegenic material (oils)
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Term
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Definition
- Drugs: Lithium
- Genetics: Cystic acne: had a parent with severe acne
- Emotional stress
- Occlusion and pressure
- Not by any food?
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Term
| Acne Vulgaris (COMMON ACNE) |
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Definition
- Duration of lesions: weeks to months
- Often worse in fall and winter
- Pain in lesions
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Term
| Acne Vulgaris: Physical Findings |
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Definition
- Open comedomes = Black
- Closed comedomes = White
- Papules or papulopustules (with or without inflammation)
- Nodules or cysts
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Term
| Acne Vulgaris: Laboratory Findings |
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Definition
- Free testosterone
- LH/FSH 3:1 ratio = Polycystic Ovarian Disease
- DHEA: adrenal source of androgens
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Term
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Definition
- Topical Antibiotics (day): clindamycin, erythromycin
- Benzoyl Peroxide Gels (day)
- Topical Retinoids (night): Pregnancy C category
- Retinoid Analog (differin)
- Tazorac Gel
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Term
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Definition
- Tetracycline: PRECAUTIONS
- Erythromycin
- Doxycycline
- Minocycline
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Term
| Treatment: Hormonal Therapy |
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Definition
- Orthro-TriCyclen
- Estrostep
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Term
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Definition
- Isotretinoin (accutane): retinoid that inhibits sebaceous gland function and keratinization
- Contraindications:
- Pregnancy Category X: tetragenicity
- Tetracycline and Accutane: pseudotumor cerebi
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Term
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Definition
- "like roses"
- Chronic
- Increased reactivity of capillaries to heat, leading to flushing and telangiectasia
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Term
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Definition
- Flushing, feel "heat" on face especially with hot liquids, spicy foods, alcohol
- Exposure to sun and heat may cause exacerbations
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Term
| Rosacea: Physical Findings |
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Definition
- Early: Tiny papulopustules; nodules
- Late: Telangiectasias
- Usually on cheeks, chin, forehead, nose
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Term
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Definition
- Prevention: reduction in alcohol and hot beverages; decrease stress
- Topical: Metrogel and cream bid
- Oral abx (add on therapy):
- Tetracycline and Doxycycline
- In severe disease: Laser surgery/Accutane
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Term
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Definition
| Chronic disease of apocrine gland-bearing skin in the axilla, anogenital region and scalp |
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Term
| Hidradenitis Suppurativa: Epidemiology |
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Definition
- Age: Puberty to Climacteric
- More females than males
- Genetics? Although no data available, mother/daughter transmission has been frequently noted
- Etiology and pathogenesis: Unknown
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Term
| Hidradenitis Suppurativa: History |
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Definition
- Intermittent pain
- Marked point tenderness secondary to abscess formation
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Term
| Hidradenitis Suppurativa: Physical Findings |
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Definition
- Lesions very tender, nodules, abscesses
- Comedomes (sometimes paired)
- Exudate drainage
- Sinus Tract Formation
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Term
| Hidradenitis Suppurativa: Laboratory Evaluation |
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Definition
| Secondary infection with Staph Aureus |
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Term
| Hidradenitis Suppurativa: Management |
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Definition
- Intralesional triamcinolone
- Oral abx: emycin, tetracycline
- Oral prednisone
- Accutane?
- Psychological Managment
- Surgical Management:
- I & D abscess
- Nodule excision
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