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Other Antivirals
MOA's & classes for all other antivirals from Buhler
22
Pharmacology
Post-Graduate
04/12/2011
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Additional Pharmacology Flashcards

 

 

Cards

Term
Acyclovir (Zovirax)
 Definition
Nuke: Inhibit Viral DNA polymerase to block viral replication
Nucleoside/nucleotide analogues
Term
Valacyclovir (Valtrex)
 Definition
Nuke: Inhibit Viral DNA polymerase to block viral replication
Nucleoside/nucleotide analogues
Term
Famciclovir (Famvir)
 Definition
Nuke: Inhibit Viral DNA polymerase to block viral replication
Nucleoside/nucleotide analogues
Term
Ganciclovir (Cytovene)
 Definition
Nuke: Inhibit Viral DNA polymerase to block viral replication
Nucleoside/nucleotide analogues
Term
Valganciclovir (Valcyte)
 Definition
Nuke: Inhibit Viral DNA polymerase to block viral replication
Nucleoside/nucleotide analogues
Term
Adefovir (Preveon)
 Definition
Nuke: Inhibit Viral DNA polymerase to block viral replication
Nucleoside/nucleotide analogues
Term
Entecavir (Baraclude)
 Definition
Nuke: Inhibit Viral DNA polymerase to block viral replication
Nucleoside/nucleotide analogues
Term
Tenofovir & Emtricitabine (Truvada)
 Definition
Nuke: Inhibit Viral DNA polymerase to block viral replication
Nucleoside/nucleotide analogues
Term
Docosanol (Abreva)
 Definition
For HSV only

inhibits membrane fusion between virus and cell
Term
Foscarnet (Foscavir)
 Definition
For CMV

Pyrophosphate analogue which blocks viral DNA Polymerase, stopping DNA replication
Term
Fomivirsen (Vitravene)
 Definition
For CMV only
Antisense DNA oligonucleotide binds viral mRNA, inhibiting protein synthesis
FYI: Antisense DNA oligonucleotide: single strands of DNA that are complementary to a chosen sequence of CMV mRNA
Term
Gardasil
 Definition
HPV Vaccine
Term
Cervarix
 Definition
HPV Vaccine
Term
Ribavirin (Rebetol)
 Definition
For Hep C
Term
PEG interferon alpha (Peg-Intron)
 Definition
For Hep C
Term
Zanamivir (Relenza)
 Definition
For Flu:
Neuroaminidase inhibitor: blocks neuroaminidase, an essential glycoprotein for penetration & budding
Term
Oseltamivir (Tamiflu)
 Definition
For Flu:
Neuroaminidase inhibitor: blocks neuroaminidase, an essential glycoprotein for penetration & budding
Term
Peramivir
 Definition
For Flu:
Neuroaminidase inhibitor: blocks neuroaminidase, an essential glycoprotein for penetration & budding
Term
Amantadine (Symmetrel)
 Definition
For Flu:

Uncoating inhibitor
(NOT Recommended)
Term
Rimantadine (Flumadine)
 Definition
For Flu:

Uncoating inhibitor
(NOT Recommended)
Term
FluMist
 Definition
For Flu only:

Live-attenuated flu vaccine
NO immuno-compromised!
Term
Inactivated influenza vaccines
 Definition
For Flu only:
inactivated virus particles or hemagglutinin
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