Shared Flashcard Set

Details

Other Agents
Other Agents
34
Pharmacology
Professional
08/19/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Bran name for Vancomycin
Definition
Vancocin
Term
Vancomycin is DOC for what?
Definition
MRSA infections: 15 mg/kg q8 - 12 hrs
Term
Vancomycin po (oral) is DOC for what?
Definition
C. difficile
Term
Vancomycin time dependent or concentration dependent killing?
Definition
Time dependent killing.
Term
What can happen if vancomycin in infused to rapidly?
Definition

Red Man Syndrome (maculopapular rash due to a too rapid infusion rate).

[image][image][image][image]

Term
What is the infusion rate for vancomycin?
Definition
3o minutes for each 500mg of drug given.
Term
Are troughs or peaks monitored for vancomycin?
Definition
troughs
Term
What are the trough levels for vancomycin?
Definition

pneumonia:    15 - 20 mcg/ml

Otherwise:      10-15 mcg/ml

Term
Does vancomycin require renal adjustment?
Definition
Yes.
Term
Brand name for Linezolid
Definition
Zyvox
Term
MOA for linezolid
Definition

binds to bacterial 23S ribosomal RNA of the 50s subunit inhibiting bacterial translation and protein synthesis.

Term
Antibiotic activity of linezolid
Definition

Treats MRSA, VRE faecium and sometimes VRE faecalis

Term
Dose adjust linezolid in renal impairment?
Definition
No
Term
Storage of linezolid oral suspension
Definition

room temperature

[image][image][image][image]

Term
Brand name for Quinupristin and Dalfopristin
Definition
Synercid
Term
MOA of synercid
Definition

binds to different sites on the 50s bacterial ribosomal subunit inhibiting protein synthesis

Term
Dose adjust synercid in renal impairment
Definition
No
Term
What are the conditions for synercid to be given peripherally?
Definition
Must be in a volume of 250 ml or greater (D5W only).
Term
What is the most common side effect of Synercid?
Definition

Phlebitis (40%)

 

Phlebitis: swelling of a vein cause by a blood clot.

Term
Brand name for Daptomycin
Definition
Cubicin
Term
Antibiotic activity of Daptomycin
Definition
Treats MRSA, VRE faecium and faecalis
Term
Dose adjust in renal impairment?
Definition
Yes
Term
Can Cubicin be used to treat pneumonias?
Definition

DO NOT USE to treat pneumonias as it is inactivate by surfactants.

Term
Is Cubicin compatible with D5W?
Definition
Compatible with NS (not D5W)
Term
Brand name for Telavancin
Definition
Vibativ
Term
What other drug is Telavancin related to?
Definition

Vancomycin. Telavancin is a lipoglycopeptide derivative of vancomycin and so its MOA is the same - inhibits bacterial cell wall synthesis.

Term
Antibiotic spectrum of Telavancin
Definition
Active against MRSA, not VRE strains
Term
Black Box Warning for Telavancin
Definition

Fetal risk, obtain pregnancy test prior to starting therapy

[image][image][image][image]

Term
Most common side effect of Telavancin
Definition
Taste disturbance (33%)
Term
Reduce dose of Telavancin in renal impairment?
Definition
Yes
Term
Brand name for Aztreonam
Definition

Azactam - IV

Cayston - inhaled for CF

Term
MOA for aztreonam
Definition
monbactam that inhibits bacterial cell wall synthesis by binding to PCPs
Term
Antibiotic coverage of Aztreonam
Definition
covers Pseudomonas and many gram (-)
Term

Can it be used in PCN - allergy pts?

Dose adjust in renal impairment?

[image][image][image][image]

Definition

Yes

Yes

Supporting users have an ad free experience!