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Details

OTC drugs: eyes
opthalmics
24
Pharmacology
Graduate
04/03/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
polymer vehicles +preservatives+inorganic electrolytes
Definition

lubricants

artificial tears

Term
cellulose ethers
Definition

lubricants

drops, artificial tears

 

Term
polyvinyl alcohol
Definition

lubricants

drops, artificial tears

 

high viscosity

low irritation

Term
povidone
Definition

lubricants

drops, artificial tears

 

hydrophilic layer on the corneal surface

low viscosity, use in combination products

Term
white petrolatum + mineral oil + lanolin
Definition

lubricants

ointments

 

blurred vision

combination therapy

Term

benzalkonium chloride (BAK) and

benzethonum chloride

 

Definition

eye preservatives

 

excellent antimicrobial activity, stability and long shelf life

 

toxic if overuse

Term
polyquad
Definition

eye preservatives

 

does not bind to contact lens

less toxic than BAK

Term
chlorhexidine
Definition

eye preservatives

 

used at lower concentration than BAK

non-toxic

Term
thimerosal
Definition

eye preservatives

 

rarely used b/c of hypersensitivity rxn

-blepharitis, conjunctivitis

Term
sodium perborate
Definition

opthalmic

disappearing preservatives

 

antimicrobial+toxicity

dissociates on contact w/ the eye forming a small amount of hydrogen peroxide(no eye irritation)

Term
purite (oxychloro complex)
Definition

opthalmic

disappearing preservatives

 

dissociates w/ eye contact

breaks down with UV light

water+ NaCl

Term
naphazoline
Definition

opthalmic decongestant

 

constricts conjunctival vessels,

reduces tearing and pain

Term
tetrahydrozoline
Definition

 

opthalmic decongestant

 

satisfactory results seen

 

Term
oxymetazoline
Definition

 

opthalmic decongestant

 

relieves itching, burning, tearing,

or foreign body sensation

 

Term
phenylepherine
Definition

opthalmic decongestant

 

low concentration OTC

Term
caution of opthalmic decongestants?
Definition

could cause dry eyes

caution in HTN,CAD, DM, cardiac diseases

b/c its a vasoconstrictor

Term
ketotifen
Definition

opthalmic antihistamine

mast cell stabilizer and H1-receptor antagonist

inhibits eosinophils

 

relief in minutes up to 12 hrs

 

basal constructive activity

 

safest

Term
pheniramine
Definition

opthalmic antihistamine

 

FDA, "less effective antihistamine"

 

available with decongestants

Term
common side effect of opthalmic antihistamine?
Definition
burning, stinging, discomfort
Term
2%, 5% sodium chloride drops
Definition

opthalmic hyperosmotic

 

increases tonicity of tear film, draws water out of cornea

Term
5% ointment formulation
Definition

opthalmic hyperosmotic

for less frequent instillation than solution

 

for bedtime

burns, stings

Term
swelling, scaling, redness of eyelid, perfuse itching
Definition
contact dermititis
Term
inflammatory condition that causes debris along eyelids.
red, scaly, thickened eyelids, loss of lashes, mild foreign body sensation, crusting upon waking
Definition
Blepharitis
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