Shared Flashcard Set

Details

OTC drugs:
allergic rhinitis and allergic conjunctivitis
28
Pharmacology
Graduate
04/03/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
1st generation antihistmine
Definition

sedating, non-selective antihistamine

prevents H1 receptor interaction

highly lipophilic

readily corss BBB

Term
2nd generation antihistamine
Definition

non-sedations, peripherally selectove

inhibit mast cell mediators and decrease cellular recruitment

lipohobic molecules

 

activate serotonin and a-adrenergic receptor and block cholinergic receptors

Term

chloropheniramine

 

Definition

antihistamine

chlor-trimeton

 

12yr

4 mg q6-8h

Term
diphenhydamine HCl
Definition

antihistamine

 

benadryl

 

12yr

25-50 mg q6-8h

 

Term
loratadine
Definition

antihistamine

 

clatitin

 

12yr

10 mg qd

Term
certirizine
Definition

antihistamine

 

zyrtec

 

12yr

10 mg qd

Term

1st generation antihistamine

ADR

Definition

anticholinergic , anti SLUD

 

CNS-related

Term

2nd generation antihistamine

ADR

Definition

non-anticholinergic

 

less CNS-related

Term
intra-nasal cromolyn sodium
Definition
anti-inflammatory drug
Term

recommended dose of

intra-nasal cromolyn sodium

Definition

one spray on each nostrils 3-6 times/day

 

takes 3-7 days for initial efficiency

2-4 weeks for maximal benefit

Term

common ADR for

intra-nasal cromolyn sodium

Definition
sneezing, nasal stinging/burning
Term

approach to treatment:seasonal allergic rhinitis

 

sneezing, rhinorrhea or itching

Definition

antihistamine

 

intranasal cromolyn

Term

approach to treatment:seasonal allergic rhinitis


sneezing, rhinorrhea or itching + congestion

Definition

antihistamine + decongestant

intra-nasal cromolyn + antihistamine

Term

approach to treatment:seasonal allergic rhinitis


nasal congestion + allergic conjunctivis

Definition

antihistamine+decongestant

intranasal cromolyn+ antihistamine

intranasal cromolyn+ opthalmic antihistamine

Term

approach to treatment:perennial allergic rhinitis

 

nasal congestion/post-nasal discharge +/- rhinorrhea


Definition
intranasal cromolyn
Term

approach to treatment:perennial allergic rhinitis

 

sneezing, rhinorrhea, itching

Definition

intranasal cromolyn

antihistamine

 

Term

approach to treatment:perennial allergic rhinitis

 

sneezing, rhinorrhea or itching + allergic conjuctivitis

Definition

opthalmic antihistamine + antihistamine

intranasal cromolyn

Term
red eye, watery discharge, itching, lid edema, no vision impairment
Definition

allergic conjuctivitis

 

use opthalmic decongestant 

Term
phenylephrine HCl
Definition

opthalmic decongestant

 

1-2 drop up to QID

Term
naphrazoline HCl
Definition

opthalmic decongestant

 

1-2 drop up to QID

 

AllClear, Allerest

Term
tetrahydrozoline HCl
Definition

opthalmic decongestant

 

1-2 drop up to Q6H

 

Murine Tears Plus, Opti-Clear

Term
oxymethazoline HCl
Definition

opthalmic decongestant

 

1-2 drop up to Q4D

 

Visine L.R.

Term
pheniramine maleate/naphazoline HCl
Definition

opthalmic antihistamine/decongestant

 

1-2 drops 3-4 times a day

 

Naphcon A, Visine-A

Term
antazoline phosphate/naphazoline HCl
Definition

opthalmic antihistamine/decongestant

 

1-2 drops 3-4 times/day

 

Vasocon A

Term
ketotifen
Definition

opthalic antihistamine/mast cell stabilizer

 

1 drop Q8-12H

 

Zaditor, Alaway

Term
naphazoline HCl/zinc sulfate
Definition

opthalmic decongestant/astringents

 

Clarif-Eye, Murine Plus

Term
Terahydrozoline HCl/zinc sulfate
Definition

 

opthalmic decongestant/astringents

 

Alabon, Naphocon, Vasocon

 

Term
Phenylephrine HCl/ zinc sulfate
Definition

 

opthalmic decongestant/astringents

 

Zincfrin

 

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