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Organic Chemistry
Organic test 3
230
Chemistry
Undergraduate 3
04/22/2013

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Cards

Term
Lactate dehydrogenase
Definition
Catalysis

Oxidized lactic acid
Term
Cyctochrome c
Definition
Catalysis

transfers electrons
Term
DNA polymerase
Definition
Catalysis

replicates and repairs DNA
Term
lysozyme
Definition
Catalysis

destroy bacteria's cell wall
Term
Ovalbumin
Definition
Storage

egg white protein
Term
casein
Definition
Storage

milk protein
Term
Ferritin
Definition
Storage

Stores iron in the spleen
Term
myoglobin
Definition
Storage

stores O2 in heart muscle
Term
immuglobulins
Definition
Protection

antibodies

quaternary structure
Term
fibrinogen
Definition
Protection

involved in blood clotting
Term
thrombin
Definition
Protection

involved in blood clotting
Term
insulin
Definition
Regulation

regulates glucose metabolism
Term
growth hormone
Definition
Regulation

stimulates growth of bone
Term
vasopressin
Definition
Regulation

increase water retention of the kidney
Term
oxytocin
Definition
Regulation

lactation, induction of labor
Term
acetylcholine receptor protein
Definition
Nerve impulse transmission

synthesized from choline and acetyl-CoA
Term
rhodopsin
Definition
involved in vision
Term
hemoglobin
Definition
transport

transport O2 in blood

quaternary structure
Term
serum albumin
Definition
transport

transport fatty acids
Term
serum globulins
Definition
transport

transport lipids (HDL, LDL)
Term
myosin
Definition
motion

thick filaments in muscle fiber
Term
actin
Definition
motion

thin filaments in muscle fibers
Term
glycoproteins
Definition
Structural

cell membranes and walls
Term
keratins
Definition
Structural

skin, hair, nails, hoofs
Term
fibroin
Definition
Structural

silk
Term
collagen
Definition
Structural

Fibrous connective tissue (tendons, teeth, bones)

quaternary structure
Term
elastin
Definition
Structural

elastic connective tissue (ligaments, artery walls)
Term
Saponifiable - simple
Definition
fats, waxes, oils
Term
Saponifiable - complex
Definition
Phospholipids, Glycolipids
Term
Non-Saponifiable
Definition
steriods, fatty acids, prostaglandins
Term
Phospholipids divide into
Definition
Phosphatides, Sphingolipids
Term
Carbohydrates metabolize into
Definition
Acetyl CoA
Term
Acetyl CoA become either
Definition
Fatty acids (Metabolism)
Cholesterol (through liver)
Term
Cholesterol comes from
Definition
some foods (eggs, butter, cheese)
Acetyl CoA
Term
Cholesterol becomes (5)
Definition
Bile salts
Vitamin D
Steroid hormones
Cell membranes
Nerve and brain tissue
Term
excess Cholesterol
Definition
to gallbladder
eliminated on bile or gallstones
Term
Oxidoreductases
Definition
Oxidases
Reductases
Dehydrogenases
Term
Transferases
Definition
Transaminases
Kinases
Term
Hydrolases
Definition
Peptidases
Lipases
Amylases
Term
Lyases
Definition
Decarboxylases
Dehydrases
Deaminases
Term
Isomerases
Definition
Isomerases
Epimerases
Mutases
Term
Ligases
Definition
Synthetases
Carboxylases
Term
Irreversible
Definition
attaches to the enzyme permenently but does not form its our reaction
Term
Non-competitive
Definition
does not attach itself to the active site , but somewhere else so it changes the structure of the enzyme
Term
Competitive
Definition
non-reactive molecule that takes the place of the usual substrate on the active site.
Can break up.
Term
Antagonists
Definition
inhibits the normal physiological function of a receptor
Term
inhibitor
Definition
effector that decreases or prevents a chemical reaction
Term
Agonist
Definition
binds to a receptor and triggers a responce by the cell.
Term
Cofactors
Definition
non-protein compound that is bound to a protein and is required for protein activity
Term
Substrate
Definition
Term
Acetylcholinesterase
Definition
Enzyme

converts Acetylcholine into inactive choline and acetate
Term
egg albumin
Definition
egg white

protein
Term
aldosterone
Definition
steroid hormone

produced by outer sections of adrenal cortex
Term
apoenzyme
Definition
enzymes that require a cofactor but do not have one bound
Term
Catalytic site
Definition
active site

portion of the enzyme where substrate molecules bind and undergo reaction
Term
cholesterol
Definition
A diet high in carbohydrates will lead to acetyl CoA formation, and that can increase cholesterol synthesis

Butter and eggs have a high level of cholesterol

can move right through cell membrane w/o a protein channel
Term
cortisone
Definition
steriod hormone

released by adreanal gland

suppresses the immune system
Term
cortisol
Definition
steriod hormone

produced by adreanal gland

increase blood sugar, suppress immune system, aid in metabolism
Term
holoenzyme
Definition
an apoenzyme with its cofactor
Term
lactic acid
Definition
milk acid

carboxylic acid

can become lactate ion

sours milk
Term
Lactose
Definition
disaccharide sugar

galactose and glucose
Term
lecithin
Definition
phospholipids in animal and plant tissue
Term
milk
Definition
lactose

lactic acid
Term
myelin
Definition
myelin sheath on neurons

lipids
Term
niacin
Definition
vitamin B3
nicotinic acid
dificiency causes pellagra

increases levels of HDL
Term
Pantothanic acid
Definition
vitamin B5

water-soluble vitamin

essential nutrient to synthesize coenzyme-A
Term
peptide bond
Definition
covalent chemical bond
carboxyl group reacts with amino group to release water
Term
phospholipase
Definition
enzyme

hydrolyzes phospholipids into fatty acids
Term
Proenzymes
Definition
inactive enzyme precursor
Term
prostaglandins
Definition
synthesized in the cell only when it is needed

made from fatty acid found in cell membranes

very potent in small quantities

they act like hormones
Term
Riboflavin
Definition
vitamin B2

micronutrients

component of cofactors FAD and FMN

role in energy metabolism and metabolism of fats, ketone bodies, carbohydrates, and proteins
Term
thiamine
Definition
vitamin B1

water-soluble vitamin
Term
Vitamin A
Definition
Lipid-soluble
Term
Vitamin C
Definition
Term
Vitamin D
Definition
Lipid-soluble
Term
Vitamin E
Definition
Lipid-soluble
Term
Vitamin K
Definition
Lipid-soluble
Term
Whey
Definition
milk serum

liquid from curdled and strained milk

Whey protein (globular protein)
Term
Zymogens
Definition
inactive enzyme precursor
Term
Saturated fats melting point
Definition
High
Term
unsaturated fats melting point
Definition
Low
Term
Unsaturated physical state at room temp
Definition
liquid
Term
saturated physical state at room temp
Definition
solid
Term
esterification
Definition
fatty acids react with alcohols to form esters and water
Term
acid hydrolysis
Definition
produce fatty acids from esters
Term
cell membranes
Definition
bilayer with the hydrophilic end on the outside

contains protein channels to allow small polar molecules and ions to move through

polypeptides cannot pass through
Term
allosteric enzymes
Definition
quaternary structure
Term
___ levels of LDL are associated with cardiovascular diease
Definition
High
Term
exercise helps ____ the LDL valuses
Definition
Lower
Term
a healthy adult should have a ___ LDL value
Definition
Low
Term
Butter and eggs have a ___ level of cholesterol
Definition
High
Term
A diet high in carbohydrates will lead to ___, and that can increase cholesterol synthesis
Definition
Acetly CoA formation
Term
Which type of bond connecting amino acids is found in the tertiary structure of proteins
Definition
salt bridges
disulfide bonds
hydrogen bonding of side chains
Term
Polar (neutral) amino acids can bond with what groups?
Definition
Polar neutral, acidic, and basic
Term
Steroid hormones
Definition
can move right through cell membrane w/o a protein channel
Term
CO2
Definition
can move right through cell membrane w/o a protein channel
Term
Once one molecule of O2 is bound to the heme of hemoglobin, hemoglobin’s ability to bind more oxygen is enhanced.  
Definition
true
Term

Enzymes usually react only with one compound in a pair of enantiomeric drugs. 

Definition
true
Term
The higher the turnover rate, the more efficient the enzyme. 
Definition
true
Term
A cofactor can be either an organic molecule or an inorganic metal, which is necessary for biological activity of an enzyme. 
Definition
true
Term
Proteins in solution are actually colloids not really solutions. 
Definition
true
Term
Sphingolipids contain a sphingosine backbone instead of glycerol. 
Definition
true
Term
Iodine test is the same as the iodine number  
Definition
false
Term
Cortisol regulates the conversion of amino acids into carbohydrates 
Definition
true
Term
Dilated blood vessels are less permeable
Definition
false

dilated blood vessels are permeable
Term
Globular proteins are much more easily denatured than tough fibrous proteins.
Definition
true
Term
Salt bridges are the strongest interaction in the tertiary structure of proteins.
Definition
False

disulfide
Term
Alcohol is a diuretic because it inhibits the secretion of vasopressin, (vasopressin increases water retention of the kidney)
Definition
true
Term
A very high pH will permanently denature enzymes but a very low pH will not.
Definition
False

both will
Term
Aldosterone and vasopressin have similar effects on water retention in the kidneys.
Definition
true
Term
The diseases Gaucher’s, Niemann-Pick and Tay-Sachs all involve the lack of enzymes needed to control lipid degradation.
Definition
true
Term
Lipids that are saponifiable all have an ester linkage.
Definition
true
Term
Hydrophilic interaction is the weakest interaction in the tertiary structure of proteins.
Definition
false

hydrophobic
Term
The redness associated with inflammation is due to the dilated blood vessels, which bring more blood into the area.
Definition
true
Term
High temperatures will permanently denature enzymes but low temperatures will not.
Definition
true
Term
Women tend to have a lower LDL value than men.
Definition
true
Term
Naturally occurring carbohydrates are usually “D”, while amino acids are usually “L”
Definition
true
Term
Acid solutions will turn red litmus paper blue
Definition
false

base solutions
Term
Anti-coagulant which is always found in the blood in small quantities
Definition
heparin
Term
Prescription drug given to patients after heart attacks as a blood thinner
Definition
coumadin
Term
Precipitates calcium ions, thus preventing blood clotting
Definition
oxalate
Term
Found in Spinach and Broccolli
Definition
Vitamin K
Term
Analgesic which is not an anti-coagulant
Definition
acetaminophen
Term
What compound causes the conversion of fibrinogen to fibrin?
Definition
thrombin
Term
Which is the actual blood clot?
Definition
fibrin
Term
Which destroys the blood clot after it is no longer needed?
Definition
plasmin
Term
Which is found in blood plasma but not blood serum?
Definition
fibrinogen
Term
Calcium ions are needed for the conversion of what compound to what compound?
Definition
prothrombin to thrombin
Term
Classify: Elastin
Definition
fibrous proteins
Term
Classify: cortisol
Definition
non-saponifiable lipids
Term
Classify: cellulose
Definition
carbohydrate
Term
Classify: aldosterone
Definition
non-saponifiable lipids
Term
Classify: Enzymes
Definition
globular proteins
Term
Classify: Phospholipids
Definition
saponifiable lipids
Term
Classify: hemoglobins
Definition
globular proteins
Term
Classify: prostaglandin
Definition
non-saponifiable lipids
Term
Classify: collagen
Definition
fibrous proteins
Term
Classify:serotonin
Definition
other
Term
Components of lecithin
Definition
glycerol
Fatty acids
phosphate and amine alcohol
Term
Components of pepsinogen
Definition
amino acids
Term
Components of glycogen
Definition
glucose
Term
Components of maltose
Definition
glucose
Term
Components of maltase
Definition
amino acids
Term
Components of Beeswax
Definition
Fatty acids
Term
Components of estrogen
Definition
steroid structure
Term
Components of arachidonic acid
Definition
Fatty acids
Term
Components of Vasopressin
Definition
amino acids
Term
Components of cornflower oil
Definition
glycerol
Fatty acids
Term
Components of triglycerides
Definition
glycerol
Fatty acids
Term
Components of polysaccharide
Definition
glucose
Term
It is one of the most abundant proteins in humans
Definition
Collagen
Term
Compound in egg yolks
Definition
lecithin
Term
Compound in egg whites
Definition
ovalbumin
Term
Protein in milk
Definition
casein
Term
Carbohydrate in milk
Definition
lactose
Term
Protein found in connective tissue
Definition
collagen
Term
protein in nails, hair, hoofs
Definition
keratins
Term
blood protein used to maintain osmotic pressure
Definition
serum albumin
Term
common name for immunoglobulins
Definition
antibodies
Term
protein found in LDLs and HDLs
Definition
serum globulins
Term
A clot that breaks loose and moves is called
Definition
embolism
Term
protein in muscle of marine mammals that contains the heme group that binds O2 for storage
Definition
myoglobin
Term
protein in muscle fiber
Definition
myosin or actin
Term
protein that stores iron in the spleen
Definition
ferritin
Term
Polypeptide used to increase water retention of the kidneys
Definition
Vasopressin
Term
Polypeptide used to induce labor
Definition
Oxytocin
Term
The same reaction in different tissues will have similar but slightly different enzymes. What are these enzymes called?
Definition
isoenzyme
Term
What is the enzyme (found in saliva and tears) that destroys a bacteria’s cell wall?
Definition
lysozyme
Term
The drug that prevents a bacteria from making its cell wall
Definition
Penicillin
Term
The drug or poison that blocks the receptor site for acetylcholine on a muscle.
Definition
Curare
Term
The drug or poison that permanently inhibits acetylcholinesterase
Definition
Nerve gas
Term
The drug or poison that prevents acetylcholine from being released on the original nerve cell
Definition
Botulism
Term
Which drug inhibits the enzyme phospholipase from releasing aracadonic acid from the cell membrane?
Definition
Cortisone (or cortisol)
Term
The drug added to penicillin to prevent the bacteria from destroying the antibiotic
Definition
Clavulinic acid
Term
What is the cofactor made from Riboflavin
Definition
FAD
Term
What is the cofactor made from Niacin
Definition
NAD
Term
What is the enzyme without its cofactors called?
Definition
Apoenzyme
Term
What active peptidase is found in the small intestines
Definition
Trypsin
Term
What is referred to as the “feast” hormone?
Definition
insulin
Term
What is referred to as the “famine” hormone?
Definition
glucagon
Term
If an enzyme’s turnover rate is very low, it is a very efficient enzyme.
Definition
false

it is a efficient enzyme
Term
Enzymes and substrates are usually held together by disulfide bonds.
Definition
false

enzymes and substrates are not usually held together by disulfide bonds
Term
Hormones and enzymes can sometimes be proteins and sometimes non-proteins.
Definition
false

enzymes can only be proteins
Term
All enzymes can be affected by substrate saturation.
Definition
true
Term
Doubling the concentration of the substrate will always double the rate of the reaction.
Definition
false

not at the point of saturation
Term
All proteins have a quaternary structure
Definition
false

not all proteins have a quaternary structure
Term
All enzymes are globular proteins
Definition
true
Term
Proteins are most soluble at their isoelectric point
Definition
false

proteins are soluble at their isoelectric point
Term
Bacteria in milk will cause the milk to become more acidic
Definition
true
Term
Denaturing with heavy metals affects the salt bridges in the globular protein
Definition
true
Term
aldosterone is a __ hormone
Definition
steroid
Term
glucagon is a ___ hormone
Definition
protein
Term
keratin is a hormone T/F
Definition
false
Term
what hormone can slide right through the cell membrane?
Definition
steroid hormone
Term
what hormone takes minutes to affect the cell
Definition
protein hormone
Term
____ hormone attaches to a receptor site on the outside of the target cell
Definition
protein hormone
Term
chemical messengers that are produced in one place in the body and affect other parts of the body
Definition
hormones
Term
maltase needs _____ enzyme for the reaction
Definition
hydrolases
Term
A tripeptide to three seperate amino acids needs _____ enzyme for the reaction
Definition
hydrolases
Term
Lactic dehydrogenase needs ____ enzyme
Definition
oxidoreductases
Term
Phosphofructokinase needs _____ enzyme for the reaction
Definition
transferases
Term
alanine transamiinase needs _____ enzyme for the reaction
Definition
transferases
Term
Acetoacetate decarboxylase needs _____ enzyme for the reaction
Definition
lyases
Term
glucose-6-phosphate to fructose-6-phosphate needs _____ enzyme for the reaction
Definition
isomerase
Term
phosphoglucomutase
Definition
isomerase
Term
Citric acid synthetase needs _____ enzyme for the reaction
Definition
ligase
Term
Oxaloacetate & acertyl-CoA to citric acid needs _____ enzyme for the reaction
Definition
ligase
Term
What vitamin is converted into the coenzyme NAD or NADH
Definition
niacin
Term
What vitamin is converted into coenzyme A
Definition
Pantothenic acid
Term
What vitamin is converted into the coenzyme FAD
Definition
Riboflavin
Term
What vitamin is needed for collagen synthesis
Definition
Vitamin C
Term
what vitamin is converted into the coenzyme TPP
Definition
thiamine
Term
Scurvy is caused by the deficiency of what vitamin
Definition
Vitamin C
Term
the rate at which an enzyme will convert substrates to products is called
Definition
Turnover rate
Term
specific area on the enzyme where the chemical reaction takes place
Definition
Catalytic site
Term
specific area on the enzyme where the substrate binds
Definition
Contact site
Term
inactive protein part (without the cofactors) of an enzyme is called
Definition
Apoenzyme
Term
what is the cofactor plus the protein part called
Definition
holoenzyme
Term
what is the cofactor that is organic but not a protein called
Definition
coenzyme
Term
What fiborous protein has a triple helix structure
Definition
collagen
Term
what protein is found in muscle fiber (2)
Definition
actin or myosin
Term
What protein is found in artery walls and ligaments
Definition
elastin
Term
what protein is used to store iron in the spleen
Definition
ferritin
Term
protein found in bones and connective tissue
Definition
collagen
Term
Protein used to store oxygen in heart muscles (humans) and marine mammal muscles
Definition
myoglobin
Term
what is milk "curds", what has precipipated out?
Definition
casein
Term
Which is the most abundant protein in the human body
Definition
collagen
Term
Protein found in nails and hoofs and hair
Definition
keratin
Term
Bacteria in milk can convert the lactose into what compound
Definition
lactic acid
Term
Enzyme found in tears and saliva that kills invading bacteria
Definition
lysozyme
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