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Organic Chemistry 1: Final
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20
Chemistry
Undergraduate 2
12/10/2008

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Term
SO3H
Definition
strong electron withdrawing = meta
Term
NO2
Definition
strong electron withdrawing = meta
Term
CN
Definition
strong electron withdrawing = meta
Term
CH3-C=O
Definition
strong electron withdrawing = meta
Term
Cl, Br, I (halogens)
Definition
weak electron withdrawing = ortho, para
Term
alkyl groups
Definition
strong electron donating groups = ortho, para
Term
OH
Definition
weak electron donating = ortho, para
Term
OCH3
Definition
weak electron donating = ortho, para
Term
NH2
Definition
weak electron donating = ortho, para
Term
electron withdrawing group
Definition
react slow (worse nucleophile)
Term
electron donating group
Definition
react fast (better nucleophile)
Term
pKa and charge
Definition
lower with charge
Term
pKa and size
Definition
lower with larger atom
Term
pKa and p character
Definition
more p character = higher pKa
Term
pKa and s character
Definition
more s character = lower pKa
Term
pKa and resonance
Definition
resonance = lower pKa
Term
hybridization and bond length trend
Definition
sp3 > sp2 > sp
Term
atom size and bond length trends
Definition
smaller atom = shorter bonds
Term
tosyl chloride plus pyridine
Definition
makes OH good leaving group

Cl-S(=0,=0)-Ph
Term
NH2 + single bond
Definition
takes H and LG and makes alkene
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