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oral micro test 2
ch 5 6 10 and vocab
134
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Pre-School
05/09/2013

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Term
substance produced by complement activation (especially C3a, C5a) that results in increased vascular permeability through release of pharmacologically active mediators from mast cells.
Definition
anaphylatoxin
Term
protein thats produced as a result of the introduction of an antigen and has ability to combine with the antigen that stimulated its production.
Definition
antibody
Term
substance that can induce a detectable immune response when introduced into an animal.
Definition
antigen
Term
bursa derived cell in avian species. precursors of plasma cells that produce antibody
Definition
B cells
Term
process where phagocytic cells are attracted to the invading pathogens. (injury site)
Definition
Chemotaxis
Term
system of serum proteins thats the primary mediator of antigen-antibody reactions.
Definition
Complement
Term
factor such a lymphokine or monokine produced by cells that affect other cells and have multiple immunomodulating functions. they include interleukins and interferons.
Definition
cytokine
Term
lysis of bacteria or of cells such as tumor cells or RBC by the insertion of the membrane attack complex derived from complement activation
Definition
Cytolysis
Term
molecule that is not immunogenic by itself but can react with a specific antibody.
Definition
Hapten
Term
sharing transplantation antigens
Definition
histocompatible
Term
The IgE is induced by allergen and binds via its Fc receptor to mast cells and basophils; after encountering the antigen again, the fixed IgE becomes cross linked, inducing degranulation and release of mediators, especially histamine. this reation is called?
Definition
Type 1. Anaphylactic (immediate)
Term
antigens on a cell surface combine with antibody. leads to complement-mediated lysis or other cytotoxic membrane damage. this type of reaction is?
Definition
type 2. cytotoxic
Term
antigen-antibody immune complexes are deposited in tissue, complement is activated, and polymorphonuclear cells are attracted to the site, causing tissue damage. this reaction is?
Definition
type 3. immune complex
Term
t cells sensitized by an antigen , release lymphokines on 2nd contact with same antigen. lymphokines induce inflammation and activate macrophages. this is what type of reaction?
Definition
type 4. delayed.
Term
development of resistance to a foreign substance. it can be antibody mediated or cell mediated or both.
Definition
immune response
Term
glycoprotein composed of H and L chains that functions as an antibody. all antibodies are considered these but not all of these have antibody functions. this is?
Definition
immunoglobulins
Term
a subdivision of immunoglobulin molecules based on unique antigenic determinants in the Fc refion of the H chains. there are 5 classes.
Definition
immunoglobulin class
Term

1. only immunoglobulin capable of crossing placenta?

 

2. 1st to appear at immune respone?

 

3. principal immunoglobulin in external secretions of mucosal surfaces?

 

4. thought to activate the B cell...

 

5. plays important role in immediate hypersensitivity reactions and parasitic infections....

Definition

1. IgG

2.IgM

3.IgA

4.IgD

5.IgE

Term
one of the heterogeneous group of low molecular weight proteins elaborated by infected host cells that protect noninfected cells from viral infection. they are cytokines.
Definition
interferon
Term
a cytokine that stimulates or otherwise affects the function of lymphocytes and some other cells.
Definition
interleukin (IL)
Term
this induces T helper cell synthese of IL-2. activates t cells. induces chemotaxis for neutrophils.
Definition
IL-1
Term
stimulates antibody synthesis, t cytotoxic cells, and NK cells.
Definition
IL-2
Term
stimulates hematopoiesis.
Definition
IL-3
Term
induces isotype switching
Definition
IL-4
Term
promotes growth and differentiation of B cells
Definition
IL-5
Term
stimulates B cell differentiation; activates T cells
Definition
IL-6
Term
promotes pre-B cell growth and pre-T cell growth
Definition
IL-7
Term
stimulates chemotaxis of neutrophils
Definition
IL-8
Term
promotes T cell growth. enhances mast cell
Definition
IL-9
Term
inhibits T helper cell 1 and cytokine release. stimulates mast cell growth
Definition
IL-10
Term
stimulates development of B cells. stimulates hematopoiesis.
Definition
IL-11
Term
activates T cells. stimulates TH1 cell development.
Definition
IL-12
Term
anti-inflammatory activity. B cell growth and differentiation.
Definition
IL-13
Term
induces proliferation of activated B cells.
Definition
IL-14
Term
stimulates growth of intestinal epithelium, T cells, and NK cells.
Definition
IL-15
Term
lymphocyte chemoattractant factor
Definition
IL-16
Term
a mononuclear cell 7 to 12 micrometers. contain nucleus with densely packed chromatin and a small rim of cytoplasm. include T cells and B cells.
Definition
lymphocyte
Term
a cytokine that is a soluble product of a lymphocyte. responsible for multiple effects in a cellular immune reaction.
Definition
lymphokine
Term
phagocytic mononuclear cell from bone marrow monocytes. found in tissues and at site of inflammation. serve accessory roles in cellular immunity
Definition
macrophages
Term
cluster of genes located close to each other. determines histocompatibility antigens of the members of a species.
Definition
Major Histocompatibility Complex (MHC)
Term
the end product of activation of the complement cascade, which contains C5, C6, C7, C8, and C9. it makes holes in the membranes of gram negative bacteria, killing them and in RBCs, it results in lysis.
Definition
Membrane Attack Complex
Term
circulating phagocytic blood cell that develops into tissue macrophages
Definition
Monocyte
Term
substance capable of enhaving phagocytosis. antibodies and complent are the 2 main ones....
Definition
opsonin
Term
the coating of an antigen or particle by substances such as antibodies, complement components, fibronectin, and so on, that facilitate uptake of the foreign particle into a phagocytic cell.
Definition
opsonization
Term
derived from a hematopoietic cell of bone marrow and is characterized by a multi-lobed nucleus. they migrate from the circulation site to a site of inflammation by chemotaxis and are phagocytic for bacteria and other particles.
Definition
polymorphonuclear cell (PMN)
Term
derived from thymus. participates in variety of cell mediated immune reactions.
Definition
T cell
Term
activates macrophages and cytotoxic and other T cells.....
Definition
TH1 or CD4 cells
Term
activates B cells to secrete immunoglobulin...
Definition
TH2 or CD4 cells
Term
destroys target cells....
Definition
TC (cytotoxic) or CD8 cells
Term
causes inflammation associated with allergic reactions and tissue transplant rejection
Definition
TD (delayed hypersensitivity) cell
Term

regulates immune response...

like a boss...

Definition
TS (surpressor) or CD8 cells.
Term
what are the principal portals of entry of infectious agents and allergens?
Definition
mouth and nose
Term
protrusion of the crown of the tooth through the oral mucosa results in a breach in the ________ of the _________
Definition
integrity of the mucosa
Term
many of the ___________ molecules are multifunctional and have overlapping activities.
Definition
salivary
Term
grandular (mucosal) secretions is saliva. its produced by what 3 glands?
Definition

1. major parotid

2. submandibular

3. sublingual 

Term
mucosal barriers expresses ____ ______ receptors
Definition
toll like
Term
signaling pattern recognition receptors that recognize repeating patterns of molecules that are conserved among pathogenic microorganisms called PAMP's
Definition
toll like receptors
Term
toll like receptors encounter with PAMP signals the epithelial cells to produce what 4 things?
Definition

cytokines

chemokines

peptide antibodies

release nitric oxide and eicosanoids

Term
rate of desquamitation related to the....
Definition
microbial burden
Term
receptors for secretory component are present on buccal epithelial cells. microorganisms captured by the tethered antibody are removed with the cells shed from the epithelium.
Definition
epithelial antibody receptors
Term
acellular organic film covering the teeth...
Definition
acquired enamel pellicle
Term
active at micromolar concentrations against bacteria, fungi, and eveloped viruses in vitro
Definition
defensins
Term
this antimicrobial protein is produced by non keratinized epithelial
Definition
calprotectin
Term
what are the 2 major types of adherent Mucin layer?
Definition
MG1 and MG2
Term
how many liters of saliva is secreted in the mouth each day by the 3 major salivary glands and by numerous minor glands?
Definition
0.5-1.5
Term

bicarbonate, chloride, potassium, and sodium.

these are all....

Definition
inorganic components of saliva
Term
digestive enzyme amylase, lubricant mucous glycoproteins, acidic protein rich and thyrosine rich proteins, humoral host defense factors, MG1 and MG2, agglutinin, von ebner gland protein, histatins, cystatins, leukocyte protease inhibitor, thrombospindin, lysozyme, peroxidase, lectoferrin, S-IgA, and TCR.....these are all......
Definition
organic components of saliva.
Term
overallshape is spherical
Definition
cocci
Term
rod shaped. some endospore forming.
Definition
bacilli
Term
combonations of 2 different shapes...
Definition
pleomorphic
Term
curved or comma shaped rods
Definition
vibrios
Term
thick, rigid, spiral organisms
Definition
spirillum
Term
thin, flexible spirals.
Definition
spirochetes
Term
bacteria can be arranged by their
Definition
shape, arrangement, and style of grouping
Term
beadlike chains are called....
Definition
streptococci
Term
produced by division within 2 planes. cocci arranged in squares of 4.
Definition
tetrads
Term
cocci arranged in cubes of 8 as a result of division in 3 planes....
Definition
sarcina
Term
graplelike clusters formed by cell division in random planes
Definition
staphylococci
Term
paired rods that remain in pairs after division....
Definition
diplobacilli
Term
fail to separate after they divide and remain in chains....these are....?
Definition
streptobacilli
Term
this results in 2 identical daughter cells. they need metabolites to divide. its a cascade of events that must occur to initiate replication. once replication is started, DNA synthesis must run to completion. when metabolites are depleted-cessation. this process is called......
Definition
binary fission
Term
bacteria have to adapt to medium before cell division. the cells are metabolically active. this is what phase?
Definition
lag phase
Term
the rate of growth increases with time. each cell introduces to medium divides by binary fission. each subsequent binary fission doubles the bacteria cells.... this is which phase?
Definition
logarithmic or exponential growth phase
Term
occurs when essential nutrients are depleted or by products of metabolism accumulate. what phase is this?
Definition
stationary phase
Term
begins when growth stops and the number of dead cells is larger than the number of viable cells. this is which phase?
Definition
death phase
Term
acquire energy from light
Definition
phototrophs
Term
acquire energy from chemical compounds
Definition
chemotrophs
Term
provides the backbone for all organic compunds. essential for all life forms.
Definition
carbon
Term
obtain carbon from atmospheric carbon dioxide
Definition
autotrophs
Term
use carbon from organic compounds
Definition
heteroptrophs
Term
use sunlight as the energy source. use carbon dioxide as their carbon source. photosynthetic bacteria, algae, and green plants are considered these...
Definition
photoautotrophs
Term
use chemical compounds as the source of energy and carbon dioxide
Definition
chemoautotrophs
Term
use sunlight for energy. use organic compounds as carbon source.
Definition
photoheterotrophs
Term
use organic compounds for both the source of energy and a carbon source....
Definition
chemoheterotrophs
Term
some bacteria can obtain nitrogen from inorganic compounds such as _______
Definition
nitrates
Term
these nutritional requirements can be met by organic compounds or inorganic salts of sulfates
Definition
sulfur and phosphorus
Term
required in trace amounts....
Definition
minerals
Term
optimal growth in moderate temps. generally between 25 degree celcius and 40 degree celcius. they like soil, human body, and animals. most bacteria fall into this classification.
Definition
mesophiles
Term
bacteria that are found in hot springs, deep sea hydrothermal vents, tropical soil composts, and hay stacks are called....
Definition
thermophiles
Term
grow very slow at 0 degree celcius but have an optimal growth range of 25 C to 30 C. abundant in nature and can cause food spoilage at fridge temps
Definition
psychrotrophs
Term
cold loving bacteria that can grow at 0 degrees celcius or lower...
Definition
psychrophiles
Term
when microorganisms with cell walls can withstand some osmotic pressure, they are referred to as.....
Definition
osmotolerant
Term
the sum of genetic material in an organism. in form of chromosome. (nonchromosomal plasmid = bacteria)
Definition
genome
Term
unit that codes for particular information on a DNA molecule is
Definition
gene
Term
single DNA molecule. includes proteins in eukaryotes.
Definition
Chromosome
Term
exact genetic makeup of an organism....this is called...
Definition
genotype
Term
observation characteristics of an organism. genotype + environment will equal this....
Definition
phenotype
Term
changes to the base pair sequence of DNA or RNA. passed on by cell division. unpredicatable event. occur naturally.
Definition
mutations
Term
an agent that causes mutations is....
Definition
a mutagen
Term
macrolesions where the order of bases are switched or inverted. produce nonsence codons.
Definition
inversions
Term
transfer of free DNA from 1 cell to another. occurs naturally in many bacterial species.
Definition
Transformation
Term
transfer of bacterial DNA from a bacteriophage into another cell
Definition
transduction
Term
transfer of genetic material during cell to cell contact. between mating cells of the same species or between closley related species.
Definition
conjugation
Term
give the order of the binomial system.....
Definition
domain, kingdom, phylum, class, order, family, genus, species
Term
group of helical, motile bacteria. twisting motions of their axial fibrils. found in various aqueous environments and in association with human or animal host. syphilis and lyme disease are considered these.
Definition
spirochetes!
Term

Treponema pallidum is....

 

borrella burgdorferi is.....

Definition

syphilis

 

 

lyme disease

Term
they are either slightly curved or have multiple helical turns. motile with help of flagella. live in fresh or coatsal waters. helicobacter pylori- peptic ulcers, gastritus, duodenitis = example. this is what?
Definition
aerobic/microaerophilic helical viroid gram negative bacteria
Term
rhizobium, legionella, neisseria, bordetella, francisella. these bacterial are all considered.....
Definition
gram negative aerobic rods and cocci
Term

these have simple nutritional requirements. found in soil, water, intestinal tracts of animals and humans.

escherichia coli is an example. 

Definition
facultative anaerobic gram negative rods
Term
can be straight, curved, helical , motile, or nonmotile. present in GI tract of humans and animals. leptotrichia buccalis and fusobacterium are examples. they are commonly found along gum liine and tooth surfaces.
Definition
anaerobic gram negative rods
Term
these often occur in pair. found in mouth, intestines, vagina. often associated with long standing gingivitis in dental patients. veillonella is example that causes rare opportunistic infections
Definition
anaerobic gram negative cocci
Term

very small gram negative bacteria. generally rod shaped but also look coccoidal. often cause disease. 

 

_________ need a vertebrate.

____________ do not infect invertebrates.

Definition

Rickettsiae.

 

chlamydiae

Term
this is known as rocky mountain spotted fever. (tick bite)
Definition
rickettsiae rickettsii
Term
urogenital infections that are usually asymptomatic in men.
Definition
chlamydiae trachomatis
Term
the smallest of the free living bacteria that do not have cell walls.....
Definition
mycoplasmas and ureaplasma
Term
include aerobic and anaerobic bacteria. range from harmless to very virulent forms.
Definition
gram positive cocci
Term
endospore forming gram positive rods and cocci include _____________ and _____________. they are important in medicine and food industry. their spores are resistant to heat and disinfectants. they are widespread in the soil.
Definition
Bacillus and Clostridium
Term
common cause of food poisoning. include free living and pathogenic species.
Definition
endospore forming gram positive rods and cocci
Term
obligate or facultative anaerobes. complex nutritional requirements. lactobacillus is example. some species of lactobacillus is used in making of yogurt, cheese, pickels, etc...
Definition
regular nonsporing gram positive rods
Term
unusual in shape (pleomorphic). mostly facultative anaerobes. actinomyces, corynebacterium diptheria = examples.
Definition
irregular nonsporing gram positive rods
Term
infections with ______________ are difficult to treat. its neither truly gram (-) or gram (+). its natually resistant to many antibiotics.
Definition
mycobacteria
Term
originate in lungs and spread to other organ systems. infection is rare. widespread in environment.
Definition
nocardioforms
Term
important source for antibiotics. gram positive. in soil and decaying vegetation. most are spore forming. infrequently cause disease.
Definition
streptomycetes
Term

these are archaea. grow in anaerobic environments (swamps, marshes, marine sediments, sludge).

produce methane ad metabolic byproduct. rapidly killed by oxygen.

Definition
methanogens
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