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Optional Final
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185
Microbiology
Undergraduate 2
04/18/2011

Additional Microbiology Flashcards

 


 

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Term
Why study Microbiology?
Definition
Although very small, microbes play significant roles in our lives.
-We have, living on and in our bodies [e.x. skin and in our mouths and intestional tract] approx. 10 times as many microbes as the total number of cells. It has been estimated that perhaps as many as 5,000 to 1,000 different spcies of microbes live on and in us. -these are known as INDIGENOUS MICROFLORA or INDIGENOUS MICROBIOTA and for the most part they benefit us.
-Other reasons listed below:
>Some of the microbes that colonize [inhabit] our bodies are known as OPPORTUNISTIC PATHOGENS
>Microbes are essential for life on this plant as know it because some microbes produce PHOTOSYNTHESIS
[note: microbes contribute more oxygen to our atmosphere than do plants.]
>Many microbes are invovled in the decomposition of dead organisms and the waste profucts of living organims. Collectively, they are referred to as DECOMPOSERS or SAPROPHYTES
>Some micrboes are capable of decomposing industrial wastes [oil spills, for example] - thus, we can use microbes- genetically engineered microbes, in some cases- to clean up after ourselves. The use of microbes in this manner is referred to as BIOREMEDIATION
>MICROBIAL ECOLOGY
>Microbes serve as important links in food chains.
>Some microbes live in the intestional tracts of animals, where they aid in the digestion of food, and in some cases, produce substances that are of value to the host - [e.x. the E.coli bacteria that live in humans intestional tract produce vitamins K and B1]
>BIOTECHNOLOGY
>Microbes cause two dieases -INFECTIOUS DIEASE AND MICROBIAL INTOXICATION
Term
Define: Opportunistic Pathogens
Definition
Do NOT cause diease under ordinary conditions, but have the potential to cause disease should the opportunity present itself.
Term
Define: Microbial Ecology
Definition
Study of the interrelationships among microbes and the world around them [other microbes, other living organims, and the nonliving environment] ex. nitrogen cycle
Term
Define: Biotechnology - give an example
Definition
The use of living organims or their derivatives to make or modify products or processes
e.x. Some bacteria and fungi produce antibiotics that are used to treat patients with infectious diseases. By defintion, and ANTIBIOTIC is a substance produced by a microbe that is effective in killing or inhibiting the growth of other microbes - the use of microbes in the antibiotic industry is an example of biotechnology.
Term
What is the difference between an INFECTIOUS DIEASE and a MICROBIAL INTOXICATION? Which one causes more illnesses and death?
Definition
An INFECTIOUS DIEASE results when a pathogen colonizes the body and subsequently causes diease while a MICROBIAL INTOXICATION results when a person ingests a toxin [poisonous substance] that has been produced by a microbe
[note:] of the two categories, infectious diseases cause far more illnesses and deaths.
Term
Define: Koch's Postulates
Definition
A series of scientific steps, proposed by Robert Koch, that must be fulfilled to prove that a specific microorgansims is the cause of a particular diease.
Term
List the 4 Koch's Postulates
Definition
1. A particular microbe must be found in all cases of the diease and must not be present in healthy animals or humans.
2. The microbe must be isolated from the dieased animal or human and grown in pure culture in the lab.
3. The same diease must be produced when the microbes from the pure culture are imcoluted into healthy susceptible laboratory animals.
4. The same microbe must be recovered from the experimentally infected animals and grown into pure culture.
Term
The sizes of bacteria and protoza are usually expressed in terms of _______?
Definition
Micrometers [um]
Term
"Spherical bacterium" [coccus; pl cocci] are approx __________ in diameter?
Definition
1um
Term
A typical "rod-shaped bacterium"[bacillus; pl., bacilli] is about ________?
Definition
1 um wide X 3 um long
[note: although som bacilli are shorter and some from very long filaments.
Term
The size of most "virsus" are expressed in terms of _______?
Definition
Nanometers [nm]
[note] most of the virsus that cause human diease range in size from ~ 10 to 300 nm [0.01-0.3 um] although some such as Ebola virus [a cause of hemorrhagic fever] can be as long as 1,000nm [1um]. Some very large protozoa reach a length of 2,000 um [2mm]
Term
In the microbiology laboratory, the sizes of cellular microbes are measured using an
Definition
OCULAR MICROMETER
Term
Microorgansims--->
-Cellular
-Acellular
Definition
-Acellular:
>Viroids
>Prisons
>Viruses

-Cellular:
>Procaryotes:
---Archaea
---Bacteria
---Cyanobacteria
>Eucaryotes
---Algae
---Protozoa
---Fungi
Term
What is the structural difference b/t Procaryotic and Eucaryotic cells
Definition
-Eucaryotic cells contain a TRUE NUCLEUS, where as procaryotic cells do not.
-Eucaryotic cells are broken down into plant [all plant, fungi, and algae] and animal cells [all animals and protozoa] - animal cells do NOT have a CELL WALL, where as plant cells have a simple cell wall [containing cellulose- a polysaccharide].
-Procaryotic cells have complex CELL WALLS [containing proteins, lipids, and polysaccharides]
and can do photosynthesis [chlorophyll]
Eucaryotic cells - Membranous structures [e.x. ER and Golgi complexes], Ribosome [80S], Chromosomes [containing DNA and proteins], Flagella and cilia [when present, have a complex structure]

Procaryotic cells- no membranous structures other than a cell wall, no nuclear membrane, cytoplasmic ribosome [70S], chromosomes [composed of DNA alone], flagella and cilia [when present, flagella have a simple twisted protein structure, NO CILIA IN PROCARYOTIC CELLS, can do photosynthesis [chlorophyll]
Term
Acellular Microbes: Viruses
What are complete virus particles called?
Definition
Virons
Term
Acellular Microbes: Viruses
How do we observe Viruses?
Definition
They are observed using electron microscope
Term
Acellular Microbes: Viruses
Most viruses range in size from _____ to _______ nm. Although some- like Ebola virus, can be up to _____um.
Definition
10 to 300; 1
Term
Acellular Microbes: Viruses
The viruses that infect bacteria are known as ?
Definition
Bacteriophages [or simply phages]
Term
Bacteriophages can be categorized by the events that occur after invasion of the bacterial cell: some are _________ phages while others are _______ phages
Definition
Virulent, temperate
Term
Acellular Microbes: Viruses
Define : Virulent bacteriophage
Definition
A bacteriophage that regularly causes lysis of the bacteria it infects; causes the lytic cycle to occur [which results in destruction of the cell]
Term
Acellular Microbes: Viruses
List the steps in the Lytic cycle
Definition
1. Attachment -the phage attaches to a protein or polysaccharide molecule [receptor] on the surface of the bacterial cell
2. Penetration - the phage injects the DNA into the bacterial cell; the capsid remains on the outer surface of the cell
3. Biosynthesis - phage genes are expressed, resulting in the production of phage pieces or parts [i.e. phage DNA and phage proteins]
4. Assembly - the phage pieces are assembled to create complete phages
5. Release - the complete phage escape from the bacterial cell by lysis of the cell
Term
Acellular Microbes: Viruses
Define: Temperate bacteriophage
Definition
A bacteriophage whose genome incorporates into and replicates with the genome of the host bacterium; also known as LYSOGENIC BACTERIOPHAGE

-unlike virulent bacteriophages, temperate bacteriophages do not immediately initiate the lytic cycle. Their DNA can remain integrated into the host cell's chromosome for generation after generation
Term
Acellular Microbes: Viruses
Are viruses considered to be alive?
Definition
Because they are not composed of cells, viruses are not considered to be living organisms. They are referred to as acellular microbes or infectious particles
Term
Acellular Microbes: Viruses
Viruses are said to have 5 specific properties that distinguish them from living cells
Definition
1. The vast majority of viruses either possess DNA or RNA, unlike living cells that possess both
2. They are unable to replicate [multiply] on their own
3.Unlike cells, they do not divide by binary fission, mitosis, or meiosis
4. They lack the genes and enzymes for energy production
5. They depend on ribosomes, enzymes, and metabolites "building blocks" of the host cell for protein and nucleic acid production
Term
The simplest of human viruses consists of nothing more than _________ surrounded by a protein coat [the capsid -which is composed of small protein units called capsomeres] plus to enclosed ______ are referred to as the __________
Definition
Nucleic acid, nucleic acid, nucleocapsid
Term
Defind Viroids.
Definition
Viroids consist of short, naked fragments of single-stranded RNA that can interfere with with the metabolism of plant cells and stunt the growth of plants, sometimes killing the plants

-Small circular, naked RNA
-Smallest known pathogens
-Viroids are infectious RNA molecules that cause a variety of plant disease. ****
Term
Define : Prions
Definition
Prions are infectious protein molecules that cause a variety of animal and human diseases.
Term
Study table 4-16 page 54
Definition
Term
Differences between Gram-positive and Gram-negative bacteria
Definition
-Gram- positive:
>blue/purple
>thick peptidoglycan in cell walls
>teichoic acids and lipoteichoic acids in cell walls
>NO lipopolysaccharide in cell walls

-Gram-negative:
>Pink/red
>Thin layer of peptidoglycan
> NO teichoic acid and lipoteichoic acids in cell walls
> Lipopolysaccharide in cell walls
Term
Algae and protozoa are referred to as __________ because they are in the kingdom Protista
Definition
protists
Term
Define:Algea and give characteristics
Definition
Eucaryotic, photosynthetic organisms that range in size from unicellular to multicellular; includes many seaweeds.

All algal cells consists of cytoplasm, a cell wall [usually], a cell membrane, a nucleus, plastids, ribosomes, mitochondria, and Golgi bodies.
>in addition some contain pellicle [thicken cell membrane], a stigma [light sensing organelle, known as an eye spot] and flagella.

note: Contain chlorophyll
Oxygenic photosynthesis

-although not plants - more closely plantlike than protozoa --ALGAE LACK TRUE ROOTS, STEMS, AND LEAVES
Term
Define: Protozoa and give characteristics
Definition
Eucaryotic microorganisms frequently found in water and soil [ free-living] some are pathogens; usually unicellular

all possess a variety of eucaryotic structures and organelles, including cell membranes, nuclei, endoplasmic reticulum, mitochondria, Golgi bodies, lysosomes, centrioles, and food vacuoles

PROTOZOA HAVE NO CHLOROPHYLL AND THEREFORE CANNOT MAKE IT'S OWN FOOD BY PHOTOSYNTHESIS.
Term
Define: Fungi and give characteristics
Definition
Eucaryotic, nonphotosynthetic microorganisms that can be either saprophytic or parasitic

Fungi are found almost everywhere on earth; some [the saprophytic fungi] living on organic matter in water and soil, and others [parasitic fungi] living on and within animals and plants.

NOT PHOTOSYNTHETIC; HAVE NO CHLOROPHYLL OR OTHER PHOTOSYNTHETIC PIGMENTS
Term
Define: The Central Dogma
define and name who proposed it
Definition
The flow of genetic information within a cell; from DNA to an mRNA molecule to a protein molecule

Francis Crick 1957
Term
The Central Dogma [also known as the "one geneone protein hypothesis'] states that: [hint: 2 things]
Definition
1. The genetic information contained in one gene of a DNA molecule is used to make one molecule of mRNA by a process known as TRANSCRIPTION

2. The genetic information in that mRNA molecule is then used to make one protein by a process known as TRANSLATION
Term
Define: phototrophs
Definition
organisms that use light as an energy source
Term
Define: Chemotrophs
Definition
organims that use inorganic or organic chemicals as an energy source
Term
Note: Chemotrophs use either inorganic or organic chemicals and can be subdivided into two categories
>chemolithotrophs
>chemorganotrophs
Definition
>Chemolithotrophs [or simply lithotrophs] : are organisms that use inorganic chemicals as an energy source

>Chemoorganotrophs [or simply organotrophs] are organims that use organic chemicals as an energy source
Term
Define: Autotrophs
Definition
organisms that use C02 as a carbon source
Term
Define: Heterotrophs
Definition
organisms that use organic compounds other than CO2 as their carbon source
Term
Define: photoautrotrophs
give examples
Definition
are organisms that use light as an energy source and CO2 as a carbon source

-some examples: plants, algae, cyanobacteria, purple and green sulfur bacteria]
Term
Define: Photoheterotrophs
Definition
use like as an energy source and organic compounds other than carbon dioxide as a carbon source
Term
Define: Chemoautrophs
Definition
use chemicals as energy and carbon dioxide as a carbon source
Term
Define: Chemohetertrophs
Definition
Use chemicals as an energy source and organic compounds other than C02 as an energy source
Term
Define: Mutations
Definition
involve changes in the base sequences of genes
Term
Define: Beneficial Mutations
Definition
are mutations that are beneficial to the organisms
Term
Define: Harmful Mutations
Definition
A mutation that leads to the production of a non-functional enzyme
-If this causes the cell to die- then it leads to LETHAL Mutation
Term
Define: Silent [Neutral] Mutation
Definition
A mutation that has no effect on the cell
Term
Define: Spontaneous Mutation
Definition
Random mutations that occur naturally
Term
Define: Mutagens
Definition
Physical or chemical agents that cause increase an mutation rate
ex. e-ray, ultraviolet light
Term
Define: Spontaneous Mutation
Definition
Random mutations that occur naturally
Term
Define: Mutagens
Definition
Physical or chemical agents that cause increase an mutation rate
ex. e-ray, ultraviolet light
Term
Define: Thermophiles
Definition
Microorganisms that grow best at high temperatures

Minimm growth temperature: 25 oC
Optimum growth temperature: 50-60 oC
Maximum Growth Temperature: 113 oC
Term
Define: Mesophiles
Definition
Microbes that grow best at moderate temperatures

Min growth temp: 10 oC
Opt growth temp: 20-40 oC
Max growth temp: 45 oC
Term
Define: Psychrophiles
Definition
organisms that "love" cold temperature

Min growth temp: -5 oC
Opt growth temp: 10-20 oC
Max growth temp: 30 oC
Term
Define: Chemically defined medium
Definition
all the ingredients are known - this is because the medium was prepared in the lab.
Term
Define: Complex Medium
Definition
One in which the exact contents are not known. Complex media contains ground up or digested extracts from animal organs which provide the necessary nutrients, vitamins, and minerals.
Term
Define: Enriched Medium
Definition
A broth or solid medium containing a rich supply of special nutrients that promotes the growth of fastidious organisms
Term
Define: Selective Medium
Definition
Has added inhibitors that discourage the growth of certain organisms without inhibiting growth of the organism being sought.
Term
Define: Differential medium
Definition
allows one to readly differentiate among the various types of organisms that are growing on the medium.
Term
Mannitol salt gar is used to screen for S. aureus. not only will S. aureus grow on MSA but it turns the orginally ________ medium to ________ because of it's ability to ferment mannitol.
Definition
Pink, yellow
Term
Define: Population Growth Curve
Definition
A bacterial population growth curve consists of four phases: a lag phase, a log phase, a stationary phase, and a death phase.
Term
Inhibiting the Growth of Microorganisms in Vitro
Define: Sterilization
Definition
Sterilization involves the destruction or elimination of all microbes [ including cells, spores, and viruses]

-[note]: when something is sterile, it is devoid of microbial life.
Term
Define: Disinfection
Definition
involves the elimination of most or all pathogens [except bacterial spores] from nonliving objects
Term
Define: Pasteurization
Definition
a method of disinfecting liquids
Term
Chemicals used to disinfect inanimate objects, such as beside equipment and operating rooms are called
Definition
Disinfectants
Term
Define: Antiseptics
Definition
solutions used to disinfect skin and other living tissues
Term
Define: Sanitization
Definition
the reduction of microbial population to levels considered safe by public health standards, such as those applied to restaurants.
Term
Agents having the suffix "-cidial" or "cide" kill organisms whereas agents having the suffix "-static" merely mean ______
Definition
inhibit the growth and reproduction
Term
Define: germicidal agent
Definition
a chemical agent or drug that kills pathogens
Term
Define: Biocidal Agent
Definition
A chemical agent that destroys living organisms
Term
Define: Microbicidal Agent
Definition
A chemical or drug that kills microorganisms
Term
Define: Bactericidal Agent
Definition
A chemical that kills bacteria
Term
Define: Sporicidal Agent
Definition
A chemical or drug that kills spores
Term
Define: Fungicidal Agents
Definition
A chemical or drug that kills fungi, including fungal spores
Term
Define: Algicidal Agents
Definition
A chemical or bacteria that to kill algae in swimming pools and hot tubs
Term
Define: Viricidal Agents
Definition
A chemical or drug that destroys viruses
Term
Define:Microbistatic Agent
Definition
A drug or chemical that inhibits reproduction or microorganisms, but does not necessarily kill them
Term
Define: Bacteriostatic Agent
Definition
one that specifically inhibits the metabolism and reproduction of bacteria.
Term
Define: Lyophilization
Definition
a good method of preserving microorganisms for future use
Term
Define: Sepsis verse Asepsis
Definition
Sepsis is the presence of pathogens in blood or tissue where Asepsis the absence of pathogens in blood or tissue
Term
Define: Aseptic techniques
Definition
Eliminate and exclude pathogens
Term
Define: Antisepsis
Antiseptic technique
Who created this technique ?
Definition
Antisepsis: The prevention of infection
Antisepsis Technique: the use of antiseptics
-John Lister in 1867
Term
What is the most common type of sterilization for inanimate objects able to withstand high temperatures?
Definition
HEAT
Term
Explain: Thermal Death Point [TDP] verse Thermal Death Time [TDT]
Definition
TDP is the lowest temp. that will kill all the organisms in a standard pure culture within a specified period
TDT is the length of time necessary to sterilized a pure culture at a specified temp
Term
Define Autoclave
Definition
large, metal pressure cooker that uses steam to destroy all microbial life
Term
TRUE OR FALSE.
Most organisms are not killed by cold temperature.
Definition
True, instead their metabolic activities are slowed.
Term
Define: Chemotherapeutic Agent
Definition
ANY drug used to treat ANY condition or disease
Term
The chemotherapueutic agents used to treat infectious diseases are collectively referred to as ____________
Definition
Antimicrobial Agents

[thus, an antimicrobial agent is any chemical [drug] used to treat infectious disease, either by inhibiting or killing pathogens in vivo.
Term
Define: Antibiotic
Definition
a substance produced by a microorganism that is effective in killing or inhibiting the growth of other microorganisms
Term
TRUE OR FALSE: all antibiotic antimicrobial agents are antibiotics
Definition
False.

Although all antibiotics are antimicrobial agents, not all antimicrobial agents are antibiotics.
Term
TRUE OR FALSE: Antibiotics are primarily antibacterial agents and are thus used to treat bacterial diseases.
Definition
True
Term
Who discovered Penicillium? [and the first antibiotic]
Definition
Alexander Fleming
Term
What are the characteristics of an ideal antimicrobial agent?
Definition
-Kill or inhibit the growth of pathogens
-Cause no damage to the host
-Cause no allergic reaction to the host
-Be stable when stored in a solid or liquid form
-Remain in specific tissues in the body long enough to be effective
-Kill the pathogens before they mutate and become resistant to it
Term
What is the difference between Synergism versus Antagonism
Definition
When the use of two antimicrobial agents to treat an infectious disease produces a degree of pathogen killing that is far greater than that achieved by either drug alone, the phenomenon is known as SYNERGISM- when the use of two drugs produces an extent of pathogens killing that is less than that achieved by either drug alone, the phenomenon is known as ANTAGONISM
Term
Mechanisms by which bacteria become resistant to antimicrobial agents
table
9-7
Definition
Term
Define: Empiric Therapy
Definition
An educated guess a physician makes - tells the pathogen and what medicine to perscribe before the acutal results come in
Term
What are some factors a physician must take in beofre he perscribes a medication based on empric therapy?
Definition
-If the lab has the idenity of the pathogen, the clinician can refer to a pocket chart
-is the patient allergic to any antimicrobial agents
-What is the age of the patient
-is the patient prego
-is the paitient and inpatient or outpatient?
-what is the site of the patient infection
Term
Define: Symbiosis
Definition
the living together or close association of two dissimilar organisms [usually two different species]
Term
Define: Neutralism
Definition
used to describe a symbiotic relationship in which neither symbiotic is affected by the relationship.
Term
Define: Neutralism
Definition
used to describe a symbiotic relationship in which neither symbiotic is affected by the relationship.
Term
Define: Microbial ecology
Definition
the study of numerous interrelationships between microorganisms and the world around them
Term
Define: Commernsalism
Definition
a symbiotic relationship that is beneficial to one symbiont and of no consequence [is not neither beneficial nor harmful] to the other
Term
Define: Mutualism
Definition
a symbiotic relationship that is beneficial to both symbionts [i.e. the relationship is mutually beneficial]
Term
Define: Parasitism
Definition
a symbiotic relationship that is beneficial to one symbiont [the parasite] and detrimental to the other symbiont [the host]
Term
TRUE OR FALSE: A person's indigenous microflora or indigenous microbiota [sometimes referred to as "normal flora"] includes all of the microbes [bacteria. fungi, protozoa, and viruses] that reside on and within that person
Definition
TRUE
Term
It is estamated that our indigenous microflora is composed of between ________ and _____ different species
Definition
500 and 1,000
Term
How many microbes live withing our bodies?
Definition
100 trillion
Term
TRUE OR FALSE: A fetus has indigenous microflora?
Definition
FALSE
Term
Define: Microbial Antagonism
Definition
Many members of our indigenous microflora serve a beneficial role by preventing other microbes from becomming established in or colonizing a particular anatomic location
Term
Define: Opportunistic Pathogens
Definition
can be thought of as organisms hanging around, awaiting the opportunity to cause infections
Term
Name two vitamins we obtain from intestinal bacteria
Definition
K and B12
Term
Define: Biotherapeutic agents [or probiotics]
Definition
Bacteria and yeasts that are ingested to restablish and stabilize the miccrobial balance within our bodies
Term
Define: Communicable disease
Definition
If the infectious disease is transmissible from one human to another
Term
Define: Contagious disease
Definition
a communicable disese that is easily transmitted from one person to another
Term
Define: Zoonotic Disease
Definition
onfectious diseases that human acquire from animal sources
Term
Define: Incidence
Definition
# of new cases of that disease
Term
Define: Mortality rate
Definition
the ratio of the number of people wo died of a particular disease during a specified time per a specified population. also known as DEATH RATE
Term
Define: Morbidity rate
Definition
the number of new cases of a particular disease during a specified time period per specifically defined population
Term
Difference bt Sporadic disease and endemic disease
Definition
A sporadic disease is a disease that occurs only occasionally [sporadically] within a population of a particular geographic area, whereas an endemic disease that is always present within a population
Term
Define: Epidemic Disease
Definition
diseases that occur in a greater than usual number of cases in a particular region, and usually occur within a relatively short period of time
Term
Name the chain of infections [hint 6]
Definition
1. A pathogen
2. a reservoir of infection
3. a portal of exit
4. a mode of transmission
5. a portal of entry
6. a susceptible host
Term
Define: Healthcare-associated infections [HAIs]
Definition
infections that are acquired WITHIN hostipals or other healthcare facilities
Term
Define: Community-Acquired Infections

[how many days?]
Definition
infections that are acquired OUTSIDE of healthcare facilities
-can be as long as up to 14 days of hostipal discharge
Term
In the United States, approximately __% of hospitzlized patients develop HAIs
Definition
5
Term
3 components of specimen quality are
Definition
1. proper specimen selection [i.e. the correct type of specimen must be submitted]
2. prooper specimen collection
3. proper transport of the specimen to the lab
Term
It has often been stated that the quality of the lab work performed in a CML can be only as good as the quality of the speciemns it receives - what does this mean?
Definition
high-quality clinical specimens are required to achieve accurate, clinically relevant lab. results
Term
In general usage, the terms infection and infectious disease are _______
Definition
synonyms
ex. the person has a ear infection
same thing as say.. the person has an infectious disease of the ear

[hint: infectious disease- disease cause by a microbe]
Term
Many microbiologists, however, reserve use of the word infection to mean?
Definition
colonization by a pathogen [i.e. when a pathogen lands on or enters a persons body and establishes residence there, then the person is infected with that pathogen
Term
Four Periods in the Course of an Infectious Disease
explain what happens
Definition
[a] incubation period
[b] prodromal period
[c]period of illness
[d] convalescent
Term
Define: host cell mechanisms
how many lines of defenses does the body have?
Definition
wyas in which the body protects itself from pathogens
-3 , the first two lines are nospecific and the third line of defense is specific
Term
First line of defense: Skin and Mucous Membranes as Physical Barriers and cellular and chamical factors
Definition
intact skin and mucous membranes serve as nonspecific host defense mechanisms by serving as physical or mechanical barriers
- the dryness, acidity, and temperature of the skin inhibit colonization and growth of pathogens; perspiration flushes them away.
Term
Define: Microbial anatagonism
Definition
When indigenous microflora prevent the establishment of arriving pathogens
Term
The body normally responds to any local injury, irritation, microbial invasion, or bacterial toxin by a complex series of events collectively reffered to as ...
Definition
Inflammation
Term
The three major events in acute inflammation
Definition
Increase in capillary diameter
Increased permeability of capillaries
Egress of leukocytes
Term
Define: Immunology
Definition
is the scientific study of the immune system and immune response
Term
The immune system is considered to be a specific host defense mechanism and the _______ line of defense
Definition
Term
Define: Immunity
Definition
resistance to infection
Term
What are the two major arms of the immune system ? define them
Definition
Humoral Immunity - always involves the production of antibodies

Cell-Mediated Immuninty- involes various cell types, with antibodies playing on a minor roll
Term
Define: acuired immunity
Definition
Immunity that results from the active production or receipt of productive antibodies during one's lifetime
Term
[acquired immunity] - if the antibodies are actually produced within the person's body the immunity is called _______ but if the person recives antibodies that were produced by another person or by more than one person, or, in some cases by an animal- such protection is usually only temporary.
Definition
Active acquired Immunity ; passive acquired immunity
Term
Two Types of Active Acquired Immunity
Definition
Natural- immunity that is acquired in response to the entry of a live pathogen into the body [i.e. in response to an actual infection]
Artificial -immunity that is acquired in response to VACCINES
Term
Two Types of Passive Acquired Immunity
Definition
Natural immunity that is acquired by a fetus when it recives maternal antibodies in the utero or by an infant when it recives its maternal antibodies contained in colostrum
Artificial passive acquired immunity - immunity that is acquired when a person recives antibodies contained in antisera or gamma globulin
Term
Where do immune responses occur?
Definition
immune responses occur at many body sites, including the spleen, lymph nodes, tonsils and adenoids
Term
Define: Antigens
Definition
foreign organic substances that are large enough to stimulate the production on antibodies
Term
Individual molecues that stimulate the production of antibodies are referred to as
Definition
Antigenic determinants or epitopes
Term
The cells that secrete antibodies are called?
Definition
plasma cells; they are derived from B cells
Term
Define Epidermis
Definition
the superficial portion of the skin
Term
Define Dermis
Definition
the inner layer of the skin, containing blood and lympathic vessels, nerves, glands, and hair follicles
Term
Define Dermatitis
Definition
inflammation of the skin
Term
Define Sebacous glands
Definition
glands in the dermis that usually open into hair follicles and secrete an oily substance known as SEBUM
Term
Define Follicultitis
Definition
Inflammation of a hair follicle,the sac that contains a hair shaft
Term
Define Sty
Definition
Inflammation of a sebacous gland that opens into a follicle of an eyelash
Term
Define Furncle
Definition
A localized pyogenic (pus producing) infection of the skin

also known as a BOIL
Term
Define Carbuncle
Definition
A deep seated pyogenic infection of the skin
Term
Chickenpox.
Reservior & Mode of Transmission
Definition
Reservior: Infected humans
Transmission: person to person contact or droplet/airborne spread
Term
Rubella (German Measles)
Reservior & Transmission
Definition
Res: infected humans
Trans: droplet spread or direct contact w/ nasophyrengeal secretions
Term
Rubeola (Measles)
Reservior & Transmission
Definition
Reser: Infected humans
Trans: airborner, droplet, direct person-person
Term
Staphyloccal Skin Infections
Res & Trans
Definition
R: Infected Humans
Trans: person w/ draining lesion or any discharge
Term
Streptococcal Skin.
Res & Trans
Definition
Res: Infected Humans
Trans: person to person via large respiratory droplets or direct contact with patients
Term
Trachoma (Chlamydia Keratoconjuntivitis)
Pathogen
Definition
C. Trachomatis
Term
Gonoccal Conjunctivitis (Gonorheal Ophtalmia)
Pathogen?
Definition
N. Gonorrhease or GC
Term
Streptoccal Pharyngitis ( Strep Throat)
Pathogen
Definition
Streptococcus pyogenes
aka Strep A
Term
Legionellosis
Pathogen, Reservior, Transmission
Definition
Legionella Pneumophilia
Environmental water sources
Trans: Aerosols produced by misting devices
Term
Tuberculosis
Pathogen, Reservior, Transmission
Definition
Mycobacterium tuberculosis
Infected Humans, rarely primates and cattle
Ariborne droplet
Term
Whopping Cough (Pertusis)
Pathogen?
Definition
Bordetella Pertusis
Term
Campylobacter Enteritis
Reservior and Transmission
Definition
Res: animals including poultry
Trans: contaminated foods, raw milk, cutting boards
Term
Salmonellosis
Reservior and Transmission
Definition
Res: wild and domestic animales
Trans: Contaminated food, beef, cattle, milk
Term
Influenza (Flu)
Reservior & Transmission
Definition
Res: Infected humans, pigs, birds
Trans: Ariborne spread and direct contact
Term
Avian Influenza (Bird Flu)
Definition
Note: Caused by Influenza A only
Res: infected wild and domesticated birds
Trans: Bird to human via infected poultry or surfaces
Term
Define Colitis
Definition
Inflammation of the colon
Term
Define Dysentry
Definition
frequent watery stools
Term
Define Enteritis
Definition
Inflammation of the intestines, usually referring to the small intestine
Term
Define Gastritis
Definition
inflammation of the stomach
Term
Define Hepatitis
Definition
Inflammation of the liver
Term
UTI.
Lower vs Upper Tract
Definition
Lower Tract: Bladder (Cystitis), Urethra, and Prostate
Upper Tract: Kidneys(Nephritis) and Ureters
Term
Define Endocarditis
Definition
Inflammation of the membrane that lines the cavaties of the heart
Term
Define Myocardium
Definition
Inflammatoin of the muscular walls of the heart
Term
What does the CNS consists of?
Definition
Brain, the spinal cord, and the meninges
Term
Define encephalitis
Definition
inflammation of the brain
Term
Define Myelitis
Definition
Inflammation of the spinal cord
Term
What causes meningitis?
Definition
Ingestion of poisons, drugs, vaccines, or a pathogen
Term
True or False.
Viral Meningitis is sometimes referred to "aseptic meningitis"
Definition
TRUE
Term
What percentage of Trichanomas is caused by vaginitis?
Definition
1/3
Term
Giardiasis.
Res & Trans
Definition
Res: Infected humans, possibly beavers and other animals that have ingested water containing giardia cysts
Trans: fecal-orals, conataminated water, person to person
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