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Opthalmic Dyes
N/A
10
Pharmacology
Graduate
10/04/2011

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Cards

Term
Which type of dye is popularly used to detect corneal abrasions?
Definition
Fluorescein Sodium-intact cornea does not dye.
Term
What test is used for detection of vascular abnormalities of the fundus?
Definition
Fluorescein Angiography
Term
What is a common side effect of fluorescein injection?
Definition
Nausea
Term
What is indocyanine green used for?
Definition
It is used as a fluorescent dye for retinal and choroidal angiography
Term
Why is indocyanine green better for choroidal angiography than fluorescein?
Definition
Indocyanine green binds to albumin in the blood, thus less leaks out into the choroid. This makes it easier to see any defects.
Term
Describe the action of Rose Bengal dye.
Definition
Rose Bengal is a derivative of fluorescein that dyes dead or degenerated epithelial cells and mucus.
Term
________________dye should be used to diagnose pts suspected of having dry eye syndromes, herpetic keratitis,  corneal abrasions and foreign bodies
Definition
Rose Bengal
Term
What is the advantage of Lissamine Green over Rose Bengal?
Definition
Effect of the dye lasts longer. Also, lissamine green is easier to see in eyes that are inflamed or hemmorhagic
Term
What is Visudyne therapy used to treat?
Definition
Wet Macular Degeneration
Term
Describe the mechanism of Visudyne therapy.
Definition
Visudyne gets injected and forms a complex with LDL molecules. Verteporfin is the active ingredient and gets attracted to abnormal veins (since they grow so much faster, they take up greater amounts of Vertporfin). A cool red laser is shined into the eye, activating the Vertporfin and essentially burning up all the new, abnormal blood vessels. 
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