Term
List the 7 common fungal infections of the mouth |
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Definition
- Candidiasis
- Histoplasmosis
- Blastomycosis
- Coccidioidomycosis
- Cryptococcus
- Mucormycosis
- Aspergillosis
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Term
Nicknames:
- San Joaquin Valley fever
- Mississippi Valley fever
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Definition
- Coccidioidomycosis
- Histoplasmosis
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Term
List the 5 types of Candidiasis |
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Definition
- Acute pseudomembranous ("thrush")
- Acute atrophic
- Chronic atrophic
(the ones below - usually cannot scrape off white plaques - reactive hyperkeratosis)
- Chronic hyperplastic
- Chronic mucocutaneous
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Term
(1) Explain how candidiasis is diagnosed
(2) Tx |
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Definition
(1) Diagnosis can be made by microscopic demonstration of the fungal hyphae and spores within the superficial epithelium.
(2) Anti-fungal & Steroid cream for angular cheilitis lesions. |
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Term
Histoplasmosis
(1) identify infectious agent
(2) prevalence
(3) Method of inoculation
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Definition
(1) Histoplasma capsulatum
(2) up to 75% of population in Mississippi Valley and NE U.S.
(3) Inhaled spores in bird droppings.
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Term
Histoplasmosis
(1) Clinical features
(2) Histologic presentation |
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Definition
(1) low grade fever, productive cough,
oral lesions appear as nodular, ulcerative or vegetative lesions on the buccal mucosa, gingiva, tongue, palate, and/or lips.
(2) granulomatous inflammation and the small (2 to 4 microns) organisms in phagocytic cells in large numbers. |
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Term
Blastomycosis
(1) infectious agent
(2) vector
(3) gender distribution
(4) 2 types |
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Definition
(1) Blastomyces dermatitidis
(2) grows as a mold in rich moist soil
(3) 9:1 male-to-female
(4) acute, chronic |
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Term
Clinical presentation
(1) acute blastomycosis
(2) chronic blastomycosis
(3) histologic presentation |
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Definition
(1) resembles pneumonia:
high fever, chest pain, malaise, night sweats
(2) more common & may mimic TB.
cutaneous lesions - erythematous nodules that enlarge and ulcerate
oral - may resemble SCC
(3) acute and granulomatous inflammation,
8 to 20 microns, doubly refractile cell wall,
may see pseudoepitheliomatous hyperplasia |
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Term
Coccidioidomycosis
(1) infectious agent
(2) location
(3) vector
(4) two forms |
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Definition
(1) Coccidioides immitis
(2) SW U.S.
(3) inhalation of dust containing spores
(4) primary nondisseminated form,
progressive disseminated form |
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Term
Coccidioidomycosis
primary nondisseminated form
(1) oral presentation
(2) prognosis
progressive disseminated form
(3) sites attacked
(4) prognosis
(5) histologic presentation |
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Definition
(1) chronic, granulomatous, nonspecific ulcers.
(2) self-limiting and runs its course in ~2 weeks.
(3) spreadds from the lungs to throughout the body.
(4) about 50% end fatally, usually as a result of meningitis.
(5) granulomatous inflammation with multinucleated giant cells.
arthrospores measuring 10-80 microns and packed with endospores. |
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