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Opt 733 Glaucoma Exam 1
Miscellaneous
30
Medical
Graduate
10/14/2012

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Cards

Term
Why are uniocular trials a bad idea in Dr Lingel's opinion?
Definition
Systemic circulation will carry plenty of medication to opposite eye, so not a true uniocular trial

Pt compliance is difficult, very confusing
Term
How should you ensure the pt understand proper drop instillation technique?
Definition
Have pt perform drop instillation in front of you
Term
What is the follw-up schedule after Rx'ing medication?
Definition
Every 2 weeks until target IOP is reached if mild or moderate

Weekly for severe
Term
Why is pre-appointing glaucoma follow-ups a good idea?
Definition
Only 30% of pts return for first follow-up. Scheduling all visits at same time increase compliance
Term
What special tests should be performed on glaucoma follow-ups if a beta blocker or adrenergic agonist has been rx'd?
Definition
BP, pulse, and lung capacty (PEFR)
Term
Relative to a pt's med schedule, when should followup IOP's be taken?
Definition
As long as possible after previous med instillation
Term
What is the typical drift for IOP after the 'honeymoon' period for IOP meds?
Definition
1-2 mmHg
Term
What is the schedule for VF's to be performed for a glaucoma pt after initial dx?
Definition
2-3 VF in first few months to establish a baseline for all then:

Annual for mild glaucoma or glc suspect

6-12 months for moderate

4-8 months for severe

Every 4-6 weeks if very unstable
Term
When and what kind of VF's should be performed if VF's are very unstable?
Definition
Every 4-6 weeks; do not do a 30-2 or 24-2 if pt has advanced peripheral loss as pt may only have a central 10* (for example)
Term
If you are using a GDX for NFL evaluation, what mitigating factors should be controlled for?
Definition
use the same instrument year to year

same ambient light level

undilated
Term
What are the four types of VF changes that indicate current medication is not working?
Definition
new defect in prev. normal area

deepening of existing defect

expansion of multiplae pre-existing scotomas joining into a single defect

generalized depression
Term
When does MD indicate progression may be occuring? Definitely occurring?
Definition
m = -0.50 --> be suspicious

m = -1.00 --> definitely progressing
Term
What is the basic premise of when a new defect can be counted as significant on a VF?
Definition
Either a cluster of non-edge points must progress 5dB or more

OR

A single non-edge point must progress 10dB or more
Term
What is the basic premise for when an existing VF defect has deepened?
Definition
3 or more clustered non-edge pts deepen 10dB or more

OR

3 non-edge points in the same defect decline 5 dB but are at P<5% compared to baseline
Term
What is the basic premise for the expansion of discrete scotomas into one scotoma?
Definition
10dB or more drop OR P<5% progression for 2 or more points inside 15* (3 if outside of 15*)
Term
What is the criteria for confirming a generalized depression?
Definition
CPSD trending over 5 or more VF

Decline of 3dB or more at ALL points on two consecutive VF

MD decline at the P<1% level and not due to cataract/media opacity/senile miosis
Term
Why do we assess endocrine systems before rx'ing glc meds?
Definition
beta blockers mask hypoglycemia (dangerous for DM1, lesser so for DM2)
Term
If the initial IOP med is ineffective, should we avoid other drugs with same mechanism of action?
Definition
No, you can try same category.
Term
If PG's or BB's don't work, what should be tried next?
Definition
Combo of the two mechanisms
Term
If combo meds fail to control IOP, what is the next step?
Definition
surgery
Term
What are the reservations regarding glc surgery?
Definition
laser therapy can diminish effectiveness of future meds
Term
When should VF be performed in mild, moderate, severe and unstable glaucoma?
Definition
mild: yearly

moderate: 6-12 months

severe 4-8 months

4-6 weeks until new baseline
Term
What is the thickness variation from test to test of a GDX?
Definition
2-4 micron repeatability
Term
What constitutes a good score for NFI? A bad score?
Definition
The higher the NFI is, the more NFL loss. 1 = good score, 99 = bad score
Term
What is the most useful single metric (according to Lonsberry) that a GDX printout provides?
Definition
NFI
Term
What is the range for a normal NVI score? Borderline? Abnormal?
Definition
Normal: 1-30

Borderline: 31-50

Suspicious: 50-70

Abnormal: >70
Term
What is modulation with regards to a GDX score? What is a good value? A bad value?
Definition
Modulation is the delta between peak and trough on the TSNIT graph. A high score is good/normal, a low score is bad/abnormal
Term
What is the inter-eye symmetry score on a GDX measuring?
Definition
Compares OD to OS and checks how congruous they are. Symmetric will be values of close to 1, asymmetric will be closer to 0.
Term
What is the spectrum of image detail between OCT machines?
Definition
Time doman such as Stratus (older) or Cirrus (newer) will have lower detail than Fourier domain (RTVue)
Term
When using a Cirrus OCT, what age range of pt's should be evaluated cautiously and why?
Definition
Over 70 has low sample size for normative database, no database for those under 19
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