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Opt 733 Glaucoma Exam 1
Dr Lingel Lecture 2
46
Medical
Graduate
09/16/2012

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Cards

Term
Does using 24 mmHg as a break point for glaucoma give reliable dx of glaucoma?
Definition
No, too many false positives AND too many false negatives
Term
Does VF alone provide reliable results for dx of glaucoma?
Definition
No, WAY too many false positives, but few false negatives
Term
What is the FIRST change usually seen in glaucoma?
Definition
ONH changes/optic atrophy
Term
Does the NFL need to be reduced by 50% before VF loss is evident?
Definition
Probably not. Study that stated that is old and the methods used were not very rigorous
Term
Are VF changes a sign of early stage glaucoma?
Definition
No, there is enough redundancy that other s/sx will present earlier
Term
What are the advantages of an FDT VF (4 things)?
Definition
Fast

Easy for pt

No operator skill necessary

Test can be performed on pt's who are not fully corrected
Term
When is an FDT abnormal(5 things)?
Definition
Defect in any of 5 central locations

two or more mild defects in outer twelve locations

One or more moderate or severe defects in outer twelve sections

>90s/eye to perform test
Term
What is the 'learning effect' with regards to VF testing?
Definition
The Humphrey test is pushing the limits of what level most pt's can respond to, so there is a learning curve for repeated tests
Term
If a defect is found on VF, what should be looked for on the ONH?
Definition
If the area of VF loss corresponds to loss of NFL In the cup
Term
Is a single VF ever used as a baseline for glaucoma progression?
Definition
No, at least 3 VF's will need to be done to reliably detect glaucoma
Term
What level of fixation losses indicate an unreliable test?
Definition
Blind spot check failed >20%

False (+) <33%

False (-) <33%
Term
On a fixation loss 'timeline' for a VF, what does an upward deviation indicate? Downward deviation?
Definition
Up = Eye moved out of primary gaze

Down = blink or could not determine eye position
Term
How does tear film affect the reliability of VF testing?
Definition
The VF machine tracks eye position by reflecting two IR lights off of cornea. Poor tear film will give a poor light reflex
Term
If the first few blind spot checks in a VF test are failed by the pt, what should the practitioner do?
Definition
Give new instructions and VF machine should be able to still get a reliable test provided they are good at blind spot checks from there on out
Term
How does the OHTS testing criteria for blind spot testing differ from the standard?
Definition
>20% is considered an unreliable test

However, >33% was considered unreliable for OHTS study
Term
How does personality type affect VF reliability?
Definition
Type A' personalities will typically have few false positives

Laid back personalities will have more false positives
Term
What is short term fluctuation with regards to VF testing?
Definition
There are 10 points that a VF machine checks at the beginning and then again at the end. How repeatable the threshold is determines what the short term fluctuation is
Term
Should short term fluctuation on VF testing be used alone to determine test reliability?
Definition
No, look at the other factors as well. In fact, short term fluctuations can be an indicator for early glaucoma
Term
How is short term fluctuation abbreviated on the VF printout?
Definition
SF
Term
Are SF results age related?
Definition
yes, it changes as we get older
Term
What is the raw data display for VF?
Definition
What the true thresholds found in VF testing were. No norming for age performed on the results yet.
Term
What is the spacing for test points on the Humphrey 30-2?
Definition
6*
Term
What is the glaucoma hemifield?
Definition
Compares points above midline to points below midline looking for symmetry. Asymmetry can lead to being tagged as either 'borderline' or 'abnormal'
Term
Is glaucoma the only dz that can trigger a positive glaucoma hemifield assessment on VF?
Definition
No, arcuate scotoma due to AION can as well. A positive simply indicates more evaluation must be done, not a definitive dx
Term
Is the gray field useful for diagnosis or analysis?
Definition
No, use for pt education
Term
What is the Total Deviation in VF testing?
Definition
Subtract the raw data from aged norms and you get total deviation
Term
What is the probability plot of total deviation in VF testing?
Definition
Determines likelihood that an anomalous point is anomalous due to pathology vs random error
Term
How do edge points compare statistically to points within central VF?
Definition
The further out in VF you go, the more unreliable and variable the results end up, so they are weighted less heavily when diagnosing for glaucoma
Term
What is Pattern Deviation?
Definition
The VF computes the 'median sensitivity' for the pts hill of vision and weights the test results around that to try and remove uniform/overall loss or increase in sensitivity compared to normal (i.e. if a pt was normal, but wearing tinted lenses)
Term
What is a common pathological condition that can cause a total deviation, but not a pattern deviation?
Definition
cataract
Term
How does senile miosis affect VF testing?
Definition
Pay more attention to the pattern deviation due to low levels of light reaching retina causing a uniform total deviation
Term
What is mean deviation?
Definition
Overall depression or elevation of sensitivity expressed as a mean value across all points
Term
What is pattern standard deviation?
Definition
Calculates overall smoothness of hill of vision.
Term
What are common types of defects found by VF in early glaucoma (4 things)?
Definition
partial arcuate

paracentral

nasal step

temporal wedge
Term
What are commontypes of defects found by VF in later stage glaucoma?
Definition
arcuate

altitudinal
Term
What is a partial arcuate scotoma?
Definition
Extends from blind spot to nasal meridian

MUST have 1 or more abnormal spots in temporal field
Term
What is a paracentral scotoma?
Definition
Defect NOT contiguous with blind spot or nasal meridian

Does NOT involve points outside 15* that are adjacent to nasal meridian
Term
What is the most common type of paracentral scotoma?
Definition
superior temporal
Term
What is a nasal step?
Definition
field loss adjacent to nasal horizontal meridian

one or more abnormal spot at or outside of 15* from center on the horizontal meridian

Cannot include more than 1 significant point in nerve fiber bundle on temporal side
Term
What are the guidelines for determining if a VF loss  pattern is a true nasal step?
Definition
Must be incongruous and not neurologic in origin (i.e. CVA, TIA)
Term
What is a temporal wedge?
Definition
Small defect temporal to blind spot in VF due to damage to nasal fibers
Term
What is an arcuate scotoma?
Definition
extends from blind spot to at least 1 point outside 15* adjacent to nasal meridian

Expect obvious ONH damage
Term
What type of VF defect will have obvous ONH damage?
Definition
Arcuate is one
Term
What is an altitudinal scotoma?
Definition
VF defect in one hemifield that respects horizontal midline

Late stage glaucoma loss
Term
What is a generalized depression in VF testing?
Definition
diffuse defect from severe nerve fiber loss

Very late stage glaucoma loss
Term
What are the six criteria for determining if VF points are significant for diagnosing glaucoma?
Definition

A single non-edge point worse than P<0.5%

 

2 or more adjacent non-edge points with at least one worse than P<1% and the other worse than P<5%

 

3 or more adjacent non-edge points at P<5%

 

2 adjacent points differ from points across the horizontal midline by at least 10dB (nasal step); edge points OK

 

CPSD is flagged

 

GHT outside normal limits

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