Term
| Preparation of this compound effectively heals peptic ulcers. |
|
Definition
| colloidal bismuth-Pepto Bismol |
|
|
Term
| This mucosal protective agent inhibits the activity of pepsin. |
|
Definition
colloidal Bismuth-pepto bismol |
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|
Term
| Colloidal Bismuth increases _____ secretion, and forms complexes with the proteins in the _____ _____ ____ to coat and protect the _____ _____. |
|
Definition
mucus necrotic mucosal tissues ulcer crater |
|
|
Term
| Does colloidal Bismuth have antimicrobial actions? |
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Definition
|
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Term
| _____ delays stomach emptying, allowing more time for an antacid to react. |
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Definition
|
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Term
| Amoxicillin is an ______ ______ penicillin. It is bacteri____, primarily against gram__. It can also be used against ______ _______ and ______ ______. |
|
Definition
- extended spectrum
- bactericidal
- +
- haemophilus influenzae
- helicobacter pylori
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|
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Term
| Clarithromycin is a bacterio____ macrolide. It has a narrow spectrum similar to _______. Clarithromycin binds to the ___S subunit of the ribosome. Clarithromycin is effective in _______ producing staphylococcus. Clarithromycin is indicated in patients with _____ allergy. |
|
Definition
static erythromycin 50 penicillinase penicillin
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|
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Term
| Clarithromycin is efective vs __ ____ and the atypical bacteria that are intracellular pathogens such as ____, _____, ______. |
|
Definition
Haemophilus influenzae chlamydia legionella Ureaplasma
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|
|
Term
- Erythromycin and clarithromycin inhibit the hepatic metabolism of _th______, __w____, __te____, As____, Car_____, C______
|
|
Definition
theophyline warfarin terfenadine astemizole carbamazepine cyclosporine |
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|
Term
| Interaction of ______ and _____ can lengthen the QT interval and cause heart problems. |
|
Definition
| terfenadine and astemizole |
|
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Term
________ may interact with digoxin as it destroys the microflora in the intestine responsible for metabolizing digoxin, leading to greater absorption from _______ _____ leading to fatal reactions. |
|
Definition
Clarithromycin enterohepatic circulation |
|
|
Term
| Tetracycline is a bacterio_____, ______ spectrum antibiotic that binds to the ___ subunit of the ribosome. Tetracyline blocks access of the ____ ___ to the ___ ribosome complex |
|
Definition
static broad 30S amino acyl tRNA mRNA |
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Term
| _____ is an effective amebiasis agent. |
|
Definition
|
|
Term
| _____ is effectively toxic vs anaerobic organisms and for anoxic and hypoxic cells |
|
Definition
|
|
Term
| Some anaerobic organisms have __-__, low redox potential electron transport proteins that participate in the _____ ____ ____ |
|
Definition
ferrodoxin-like electron removal reactions
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|
|
Term
| What is the agent of choice in treating pseudomembranous colitis? |
|
Definition
|
|
Term
| _______ is the agent of choice in the treatment of entamoeba histolytica and is effective against trophozites, giardia lambia, and trichomonas vaginalis in males and females. |
|
Definition
|
|
Term
| What is the agent of choice in the treatment of Anaerobic G+ cocci, anaerobic G- bacilli, viz Clostridia (pseudomembranous colitis) and the brain abscesses caused by these agents. |
|
Definition
|
|
Term
| What antibiotic is preferred in the seriously ill patient if the patient does not respond to metronidazole? |
|
Definition
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|
Term
| Although resistance is not significant at this time, there have been reports that strains of ______ have been found to be resistant to metronidazole. |
|
Definition
|
|
Term
| Metronidazole is usually administered with a ____ ____ such as ____ _____ in the treatment of amebiasis. It distributes well throughout the body and can cross the BBB. |
|
Definition
luminal amebicide diloxanide furoate |
|
|
Term
Metronidazole is metabolized by the liver by _____ and ____ ____ ____, followed by ________. |
|
Definition
oxidation mixed function oxidases glucuronidation
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|
|
Term
| What is the drug of choice in the treatment of anaerobic gram-positive bacillus Clostridium dificile? |
|
Definition
|
|
Term
Concomitant treatment of metronidazole with drugs that are inducers of mixed function oxidase system such as phenobarbital ____ the rate of metabolism. Conversely drugs that inhibit the mixed function oxidase system such as cimetidine ____ _____ the half life of the drug. |
|
Definition
|
|
Term
| If taken with alcohol, metronidazole induces a ______ effect, flusing, tachycardia, hyperventilation, nausea and vomitting due to the accumulation of ______ in the blood. |
|
Definition
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