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Opt 213 Biochemistry
Oct 31 lecture
13
Other
Not Applicable
11/10/2007

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Cards

Term
What form of vitamin A is responsible for transport in the blood and what type of protein is it bound to in the blood versus intracellular transport?
Definition
retinol is bound to PA(Pre-Albumin) in the blood circulation whereas it is always bound to RBP(Retinol Binding Protein) for transport within the cell.
Term
What form of vitamin A has local hormone effects?
Definition
retinol
Term
What form of vitamin A is primarily for storage?
Definition

Retinyl ester

Term
What form of vitamin A is responsible for visual transduction?
Definition

Retinal

Term
What form of vitamin A is involved in DNA synthesis?
Definition
retinoic acid
Term
What is the term for an extremly dry eye that can result in blindness and is due to vitamin A deficiency?
Definition
xerosis
Term

What are three potential side effects of vitamin A deficiency?

Definition

1)  nyctalopia-night blindness, perhaps long dark adaptation times

2)  xerosis-extreme dry eye leading to blindness

3)  keratomalica-degeneration of corneal epithelium to the point of holes in it leading to blindness

Term
What is SOD?
Definition
an antioxidant in the disc cell membrane that protects DHA
Term
Which carbon is missing a hydroxy group in deoxyribose?
Definition
Carbon 2
Term
What do you call adenine + sugar only?  Guanine + sugar only?  Cytosine + sugar?  Thymine + sugar?
Definition

adenosine

guaonosine

cytidine

thymidine

 

All are nucleosides.

 

Term
What two enzymes hydrolyze the RNA portion of the primer and complete the gaps of the Okazaki fragments to form a continuous strand?
Definition
DNA polymerase I and ligase
Term
What form must ribose be converted to be activated for incorporation into a nucleotide?
Definition
PRPP (5-phosphoribosyl-1-pyrophosphate)
Term
Does mRNA contain introns?
Definition
No, they are spliced out before hRNA becomes mRNA.
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