Term
|
Definition
supraspinal analgesia
miosis
resp depression
euphoria
physical and behav dependence |
|
|
Term
|
Definition
spinal analgesia
weak miosis
sedation |
|
|
Term
| these have a high affinity for delta receptors |
|
Definition
|
|
Term
| has a high affinity for delta and mu rec |
|
Definition
|
|
Term
| has a high affinity for delta and mu rec |
|
Definition
|
|
Term
|
Definition
|
|
Term
| opiate affect on resp depression |
|
Definition
| decreased response to CO2 and dec automaticity |
|
|
Term
|
Definition
stimulation of Edinger westphal nucleus
**Meperidine is exception** |
|
|
Term
|
Definition
| increased tone and decreased motility |
|
|
Term
| this increases potency of opiates |
|
Definition
|
|
Term
| this produces antags in opiates |
|
Definition
|
|
Term
| this greatly increases potency |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
5-10 more potent than morphine
great lipid solubility |
|
|
Term
|
Definition
good oral analgesic
maintenance med |
|
|
Term
|
Definition
short duration of action
anti-cholinergic effects
metabolite is excitatory and cannot be treated by antags |
|
|
Term
|
Definition
VERY potent and short acting
stimulant in horse racing |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
antag/partial ag at mu
activation of kappa receptors |
|
|
Term
|
Definition
antag at kappa receptor
alternative in methadone maintenance |
|
|
Term
|
Definition
weak partial ag at mu
release serotonin
blocks norep uptake
**RLS, acid reflux, and fibromyalgia** |
|
|
Term
|
Definition
mu antag
blocks kappa at higher doses
precipitation of w/d |
|
|
Term
|
Definition
longer acting antag
maintenance therapy who are not physcially dependent |
|
|
Term
| opioid treatment of diarrhea |
|
Definition
| loperamide and diphenoxylate |
|
|
