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Opiod & Non-Opiod
Pharmacology Vocabulary
17
Other
Undergraduate 3
01/24/2009

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Term

ANALGESIC

Definition

An agent that alleviates pain without causing loss of consciousness.

Term
OPIOID
Definition
Originally, a term denoting synthetic narcotics resembling opiates but increasingly used to refer to both opiates and synthetic narcotics.
Term
ANTI-INFLAMMATORY
Definition
Counteracting or suppressing inflammation.
Term
ANTIPYRETIC
Definition

An agent that relieves or reduces fever.

 

Synonym: antifebrile, antithermic, febrifuge.

Term
NARCOTIC
Definition
An agent that produces insensibility or stupor, applied especially to the opioids, i.e. To any natural or synthetic drug that has morphine like actions. Alter perception of pain; depress respiration & the cough reflex; cause smooth muscle spasm, decreased peristalsis, emisis, & nausea.
Term
TOLERANCE
Definition

1. The ability to endure unusually large doses of a drug or toxin.

2. Acquired drug tolerance, a decreasing response to repeated constant doses of a drug or the need for increasing doses to maintain a constant response.

Term
PHYSICAL DEPENDENCE
Definition
 Substance dependence in which there is evidence of tolerance, withdrwal, or both.
Term
ABSTINENCE SYNDROME
Definition
the physical & psychological withdrawal symptoms experienced by a chemically dependent person who is suddenly deprived of a regular intake of alcohol or other addictive substance
Term
ADDICTION
Definition
Compulsive, uncontrollable dependence on a chemical substance, habit, or practice to such a degree that either the means of obtaining or ceasing use may cause severe emotional, mental, or physiologic reactions
Term

DRUG ABUSE

Definition

The use of a drug for a nontherapeutic effect.

 

Use of a drug for a reason other than which it was intended or in a manner or in quantities other than directed. Drug dependence is a compulsion to take a drug to produce a desired effect or prevent unpleasant effects when the drug is withheld.

Term

AGONIST

Definition
A drug that has affinity for and stimulates physiologic activity at cell receptors normally stimulated by naturally occurring substances, thus triggering a biochemical response.
Term
ANTAGONIST
Definition
A substance that tends to nullify the action of another, as a drug that binds to a cell receptor without eliciting a biological response.
Term

ASPIRIN - action

 

Salicylates 

Antiplatelet Drug

Cyclooxygenase (COX) Inhibitor

First-Generation NSAID

Antipyretics, Nonopioid analgesic

 

 

 

Definition

Action

[image]
Produce analgesia and reduce inflammation and fever by inhibiting the production of prostaglandins.
[image]Aspirin Only: Decreases platelet aggregation.
Therapeutic Effects: Analgesia. Reduction of inflammation. Reduction of fever. Aspirin: Decreased incidence of transient ischemic attacks and MI.

Term
ASPIRIN - Therapeutic Effect
Definition
  • Inflammation 
  • Mild to moderate pain.
  • Fever.
     
  • Aspirin: Prevents MI & Stroke 
Term
ASPIRIN - adverse effects by class
Definition

EENT: tinnitus.
GI: GI BLEEDING, dyspepsia, epigastric distress, nausea, abdominal pain, anorexia, hepatotoxicity, vomiting.
Derm: salsalate: EXFOLIATIVE DERMATITIS, STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS.
Hemat: aspirin: anemia, hemolysis, increased bleeding time. Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS AND LARYNGEAL EDEMA

Bleeding, gastric ulceration, renal impairment, Not used in children, Fetal harm, hypersensitivity in pts w/allergies

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