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An agent that alleviates pain without causing loss of consciousness. |
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Originally, a term denoting synthetic narcotics resembling opiates but increasingly used to refer to both opiates and synthetic narcotics. |
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Counteracting or suppressing inflammation. |
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An agent that relieves or reduces fever. Synonym: antifebrile, antithermic, febrifuge. |
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An agent that produces insensibility or stupor, applied especially to the opioids, i.e. To any natural or synthetic drug that has morphine like actions. Alter perception of pain; depress respiration & the cough reflex; cause smooth muscle spasm, decreased peristalsis, emisis, & nausea. |
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1. The ability to endure unusually large doses of a drug or toxin. 2. Acquired drug tolerance, a decreasing response to repeated constant doses of a drug or the need for increasing doses to maintain a constant response. |
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Substance dependence in which there is evidence of tolerance, withdrwal, or both. |
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the physical & psychological withdrawal symptoms experienced by a chemically dependent person who is suddenly deprived of a regular intake of alcohol or other addictive substance |
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Compulsive, uncontrollable dependence on a chemical substance, habit, or practice to such a degree that either the means of obtaining or ceasing use may cause severe emotional, mental, or physiologic reactions |
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The use of a drug for a nontherapeutic effect. Use of a drug for a reason other than which it was intended or in a manner or in quantities other than directed. Drug dependence is a compulsion to take a drug to produce a desired effect or prevent unpleasant effects when the drug is withheld. |
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A drug that has affinity for and stimulates physiologic activity at cell receptors normally stimulated by naturally occurring substances, thus triggering a biochemical response. |
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A substance that tends to nullify the action of another, as a drug that binds to a cell receptor without eliciting a biological response. |
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ASPIRIN - action Salicylates Antiplatelet Drug Cyclooxygenase (COX) Inhibitor First-Generation NSAID Antipyretics, Nonopioid analgesic |
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Definition
Action
[image]Produce analgesia and reduce inflammation and fever by inhibiting the production of prostaglandins. [image]Aspirin Only: Decreases platelet aggregation. Therapeutic Effects: Analgesia. Reduction of inflammation. Reduction of fever. Aspirin: Decreased incidence of transient ischemic attacks and MI. |
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ASPIRIN - Therapeutic Effect |
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ASPIRIN - adverse effects by class |
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Definition
EENT: tinnitus. GI: GI BLEEDING, dyspepsia, epigastric distress, nausea, abdominal pain, anorexia, hepatotoxicity, vomiting. Derm: salsalate: EXFOLIATIVE DERMATITIS, STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS. Hemat: aspirin: anemia, hemolysis, increased bleeding time. Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS AND LARYNGEAL EDEMA Bleeding, gastric ulceration, renal impairment, Not used in children, Fetal harm, hypersensitivity in pts w/allergies |
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